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T77052Latikafusp;化合物 LatikafuspLatikafusp
Latikafusp (AMG 256), a bifunctional fusion protein, combines a PD-1-targeting antibody with an IL-21 mutein, facilitating IL-21 pathway stimulation in PD-1+ cells. It aims to enhance and sustain the functionality of cytotoxic and memory T cells, thereby inducing anti-tumor immunity. This compound shows promise for research in solid tumors [1] [2].
价 格:¥电议型 号:T77052产 地:中国大陆
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T76888Quetmolimab;奎莫利单抗E-6011|||KANAb 001;E-6011|||KANAb 001
Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.
价 格:¥电议型 号:T76888产 地:中国大陆
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T76381H1-7 (histone H1 phosphorylation site), PKA Substrate;化合物 H1-7 (histone H1 phosphorylation site), PK
H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].
价 格:¥电议型 号:T76381产 地:中国大陆
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T76345Kaliotoxin (1-37);化合物 Kaliotoxin (1-37)Kaliotoxin (1-37)
Kaliotoxin (1-37), a toxin derived from the scorpion Androctonus mauretanicus mauretanicus, acts as a potent blocker of calcium-dependent potassium channels [1].
价 格:¥电议型 号:T76345产 地:中国大陆
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T76251Ac-FEID-CMK;化合物 Ac-FEID-CMKAc-FEID-CMK
Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in vivo. Additionally, it suppresses the caspy2-mediated noncanonical inflammasome pathway [1].
价 格:¥电议型 号:T76251产 地:中国大陆
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T75888PKA Inhibitor Fragment (6-22) amide TFA;PKA Inhibitor Fragment (6-22) amide三氟乙酸盐PKI-(6-22)-amide TFA
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhibitor (Ki: 2.8 nM).PKA Inhibitor Fragment (6-22) amide TFA reverses the pain-relieving effects of low levels of morphine in mice.
价 格:¥电议型 号:T75888产 地:中国大陆
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T75882[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA;化合物 [Lys5,MeLeu9,Nle10]-NKA(4-10) TFA[Lys5,MeLeu9,Nle10]-NKA(4-10)
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a potent and highly selective NK2 receptor agonist, exhibiting an IC50 value of 6.1 nM [1].
价 格:¥电议型 号:T75882产 地:中国大陆
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T75146KAT6-IN-1;化合物 KAT6-IN-1KAT6-IN-1
KAT6-IN-1 is a potent KAT6 inhibitor. KAT6-IN-1 can be used in research of cancer [1] .
价 格:¥电议型 号:T75146产 地:中国大陆
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T75107CrBKA;化合物 CrBKACrBKA
CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .
价 格:¥电议型 号:T75107产 地:中国大陆
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T75084Foslevcromakalim;化合物 FoslevcromakalimFoslevcromakalim
Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].
价 格:¥电议型 号:T75084产 地:中国大陆
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T74206Kalimantacin A;化合物 Kalimantacin AKalimantacin A
Kalimantacin A, a potent antibiotic, exhibits effective antibacterial activity against Staphylococcus, including methicillin-resistant Staphylococcus aureus (MRSA) [1] [2].
价 格:¥电议型 号:T74206产 地:中国大陆
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T74199Beauverolide Ka;化合物 Beauverolide KaBeauverolide Ka
Beauverolide Ka, a cyclotetradepsipeptide derived from the Beauveria bassiana fungus, enhances glucose absorption in rat L6 myoblasts cultured at a concentration of 50 μM and exhibits protective effects on HEI-OC1 cells at 10 μM. It demonstrates dose-dependent activities in both L6 myoblasts and myotubes [1] [2].
价 格:¥电议型 号:T74199产 地:中国大陆
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T74067Poly (I:C):Kanamycin (1:1) (sodium);化合物 Poly (I:C):Kanamycin (1:1) (sodium)Poly (I:C):Kanamycin (1:1
Poly(I:C):Kanamycin (1:1) sodium is a symmetric complex combining Poly(I:C) sodium, a synthetic double-stranded RNA analog acting as a TLR3 and RIG-I/MDA5 agonist, with Kanamycin, an antibacterial agent effective against both Gram-negative and positive bacteria by inhibiting translocation and causing miscoding on the 70S ribosomal subunit. Poly(I:C) sodium serves as a potent vaccine adjuvant, bolstering innate and adaptive immunity and prompting apoptosis in cancer cells [1] [2]. Meanwhile, Kana
价 格:¥电议型 号:T74067产 地:中国大陆
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T74064ent-Kaurene;化合物 ent-Kaureneent-Kaurene
Ent-Kaurene, a diterpenoid, induces ROS (reactive oxygen species) accumulation by targeting antioxidant proteins and depleting GSH (glutathione), leading to apoptosis and ferroptosis [1].
价 格:¥电议型 号:T74064产 地:中国大陆
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T73674Poly (I:C):Kanamycin (1:1);化合物 Poly (I:C):Kanamycin (1:1)Poly (I:C):Kanamycin (1:1)
Poly(I:C):Kanamycin (1:1) is a compound comprising an equal mixture of synthetic double-stranded RNA (dsRNA), specifically Poly(I:C), a Toll-like receptor 3 (TLR3) agonist, and kanamycin, a positively charged (poly-NH3) antibiotic. The positive charge of kanamycin interacts with the negatively charged Poly(I:C), stabilizing the molecule.
价 格:¥电议型 号:T73674产 地:中国大陆
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T73611Kallikrein;化合物 KallikreinKallikrein
Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .
价 格:¥电议型 号:T73611产 地:中国大陆
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T73412AAF-CMK;化合物 AAF-CMKAAF-CMK
AAF-CMK, a tripeptidylpeptidase II (TPPII) inhibitor, exhibits anti-tumor activity and induces apoptosis, making it applicable in leukemia research.
价 格:¥电议型 号:T73412产 地:中国大陆
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T73307TrkA-IN-4;化合物 TrkA-IN-4TrkA-IN-4
TrkA-IN-4, a potent, orally active and allosteric TrkA inhibitor, is a prodrug of TrkA-IN-3 . TrkA-IN-4 exhibits potent antinociceptive effects [1] .
价 格:¥电议型 号:T73307产 地:中国大陆
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T73306TrkA-IN-3;化合物 TrkA-IN-3TrkA-IN-3
TrkA-IN-3 is a potent, subselective, and allosteric inhibitor of TrkA, demonstrating significant potency with an IC50 of 22.4 nM. It exhibits over 8000-fold selectivity towards TrkA in comparison to TrkB and TrkC, making it a valuable compound for pain research.
价 格:¥电议型 号:T73306产 地:中国大陆
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T73110PI3Ka-IN-5;化合物 PI3Ka-IN-5PI3Ka-IN-5
PI3Ka-IN-5 is a potent PI3Kα/mTOR inhibitor, with an IC 50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer [1] .
价 格:¥电议型 号:T73110产 地:中国大陆