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T11824LLLanraplenib;化合物LanraplenibGS-9876;GS-9876
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
价 格:¥电议型 号:T11824LL产 地:中国大陆
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T11824LLanraplenib monosuccinate;化合物 T11824LGS-9876 monosuccinate;GS-9876 monosuccinate
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.
价 格:¥电议型 号:T11824L产 地:中国大陆
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T11824Lanraplenib succinate化合物 T11824GS-9876 succinate
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.
价 格:¥电议型 号:T11824产 地:中国大陆
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T1168Desonide地索奈德Tridesilon|||地索奈德|||Locapred|||Prednacinolone
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-
价 格:¥电议型 号:T1168产 地:中国大陆
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T11506Guaiapate;愈创哌特Mg 5454|||Klamar;Mg 5454|||Klamar
Guaiapate has an antitussive and sedative effect.
价 格:¥电议型 号:T11506产 地:中国大陆
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T11487LFiboflapon sodium;化合物 T11487LGSK2190915 sodium salt|||AM-803 sodium;GSK2190915 sodium salt|||AM-803
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
价 格:¥电议型 号:T11487L产 地:中国大陆
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T11487Fiboflapon;化合物FiboflaponGSK2190915|||AM-803;GSK2190915|||AM-803
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.
价 格:¥电议型 号:T11487产 地:中国大陆
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T11465Lenacapavir;化合物LenacapavirGS-6207;GS-6207
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
价 格:¥电议型 号:T11465产 地:中国大陆
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T11353LGallopamil hydrochloride;化合物Gallopamil hydrochlorideMethoxyverapamil hydrochloride;Methoxyverapamil
Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
价 格:¥电议型 号:T11353L产 地:中国大陆
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T11353Gallopamil;戈洛帕米Methoxyverapamil;Methoxyverapamil|||戈洛帕米
Gallopamil (Methoxyverapamil) inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist.
价 格:¥电议型 号:T11353产 地:中国大陆
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T11314Fosmanogepix;化合物 T11314APX001|||E1211;APX001|||E1211
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.
价 格:¥电议型 号:T11314产 地:中国大陆
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T11264FAPI-4;化合物 T11264FAPI-4
Api-4 is a fibroblast activated protein (FAP) inhibitor used in cancer research.
价 格:¥电议型 号:T11264产 地:中国大陆
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T11263FAPI-2;化合物 T11263FAPI-2
Fapi-2 is a fibroblast activated protein (FAP) inhibitor used in cancer research.
价 格:¥电议型 号:T11263产 地:中国大陆
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T11241p38 MAPK-IN-2;化合物 T11241p38 MAPK-IN-2
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
价 格:¥电议型 号:T11241产 地:中国大陆
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T11221ERAP1-IN-1;化合物ERAP1-IN-1ERAP1-IN-1
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activity toward a nonamer peptide representative of physiological substrates.
价 格:¥电议型 号:T11221产 地:中国大陆
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T11207Entacapone sodium salt;恩他卡朋钠盐Entacapone sodium salt
Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapone (< 100 μM) is a potent inhibitor of α-syn and β-amyloid (Aβ) oligomerization and fibrillogenesis, and also protects against extracellular toxicity induced by the aggregation of both proteins in PC12 cells.Entacapone sodium salt is a specific, potent, peripherally acting catech
价 格:¥电议型 号:T11207产 地:中国大陆
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T11193Enalaprilat-d5 sodium;依那普利拉钠 D5MK-422 D5 Sodium Salt|||Enalaprilat D5 Sodium Salt;MK-422 D5 Sodium S
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
价 格:¥电议型 号:T11193产 地:中国大陆
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T1115Doxylamine succinate;琥珀酸多西拉敏Decapryn;琥珀酸多西拉敏|||Decapryn
Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of the gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug a
价 格:¥电议型 号:T1115产 地:中国大陆
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T11114Duloxetine metabolite Para-Naphthol Duloxetine;度洛西汀代谢物Para-Naphthol duloxetine;度洛西汀代谢物|||Para-Naphth
Para-Naphthol Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI),is a metabolite of Duloxetine.
价 格:¥电议型 号:T11114产 地:中国大陆
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T11090MC-DOXHZN;化合物 T11090Doxorubicin(6-maleimidocaproyl)hydrazone;Doxorubicin(6-maleimidocaproyl)hydrazon
Mc-doxhzn is a protein-binding prodrug of DOXUbicin (DNA topoisomerase II inhibitor) with acid sensitivity.
价 格:¥电议型 号:T11090产 地:中国大陆