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T10672Capzimin;化合物CapziminCapzimin
Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.
价 格:¥电议型 号:T10672产 地:中国大陆
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T10634Bunaftide;丁萘夫汀Bunaphtide|||Meregon|||Bunaftine;Bunaphtide|||Meregon|||Bunaftine
Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.
价 格:¥电议型 号:T10634产 地:中国大陆
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T1062Capsaicin;辣椒素Qutenza|||8-Methyl-N-vanillyl-trans-6-nonenamide|||Vanilloid|||(E)-Capsaicin|||Zostrix;
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
价 格:¥电议型 号:T1062产 地:中国大陆
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T10504Implitapide Racemate;化合物 T10504Implitapide Racemate
Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
价 格:¥电议型 号:T10504产 地:中国大陆
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T10483Lisaftoclax;化合物LisaftoclaxBcl-2/Bcl-xl inhibitor 1|||APG-2575;Bcl-2/Bcl-xl inhibitor 1|||APG-2575
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
价 格:¥电议型 号:T10483产 地:中国大陆
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T10444TAK1/MAP4K2 inhibitor 1;化合物 T10444TAK1/MAP4K2 inhibitor 1
TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFβ-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
价 格:¥电议型 号:T10444产 地:中国大陆
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T10435Linaprazan;利那拉生AZD0865;利那拉生|||AZD0865
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
价 格:¥电议型 号:T10435产 地:中国大陆
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T10366Arg-Gly-Asp-Ser化合物 T10366Fibronectin tetrapeptide|||RGDS peptide
Arg-Gly-Asp-Ser is an integrin-binding sequence that inhibits integrin receptor function. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, MMP-9, and iNOS.
价 格:¥电议型 号:T10366产 地:中国大陆
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T10355Apyramide;化合物ApyramideApyramide
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.
价 格:¥电议型 号:T10355产 地:中国大陆
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T10354APX-115;化合物APX-115Ewha-18278;Ewha-18278
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
价 格:¥电议型 号:T10354产 地:中国大陆
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T10353APX-115 free base;化合物APX-115 free baseEwha-18278 free base;Ewha-18278 free base
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
价 格:¥电议型 号:T10353产 地:中国大陆
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T10352APTO-253;化合物APTO-253LOR-253|||LT-253;LOR-253|||LT-253
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
价 格:¥电议型 号:T10352产 地:中国大陆
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T10351Aprocitentan D4;化合物 T10351ACT-132577 D4;ACT-132577 D4
Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).
价 格:¥电议型 号:T10351产 地:中国大陆
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T10348Apigenin-7-diglucuronide;化合物 T10348Apigenin-7-diglucuronide
Apigenin-7-diglucuronide is a flavonoid glycoside that exists in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. It protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation.
价 格:¥电议型 号:T10348产 地:中国大陆
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T10347LApidaecin IB acetate;化合物Apidaecin IB acetateApidaecin IB acetate (123276-94-8 Free base);Apidaecin I
Apidaecin IB acetate is an insect antibacterial peptide. The minimum concentration of apidaecin IB acetate against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922) is 8 μM.
价 格:¥电议型 号:T10347L产 地:中国大陆
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T10347Apidaecin IB;化合物 T10347Apidaecin IB
Apidaecin IB is an insect antimicrobial peptide, with MIC values of 8 μM for E. coli (O18K1H7, ML35 and ATCC 25922).
价 格:¥电议型 号:T10347产 地:中国大陆
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T10346Apelin agonist 1;化合物 T10346Apelin agonist 1
Apelin agonist 1 is an oral selective apelin agonist AM-2995, an agonist of the APJ (APLNR, angiotensin receptor like-1) receptor. It may be used in the treatment of cardiovascular conditions.
价 格:¥电议型 号:T10346产 地:中国大陆
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T10345Apcin-A;化合物 T10345Apcin-A
Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.
价 格:¥电议型 号:T10345产 地:中国大陆
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T10344AP521;化合物 T10344AP521
AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).
价 格:¥电议型 号:T10344产 地:中国大陆
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T10343AOH1160;化合物AOH1160N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide;N-(2-Oxo-2-(2-phenoxyphenyla
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
价 格:¥电议型 号:T10343产 地:中国大陆