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T16566Propyl pyrazole triol;化合物Propyl pyrazole triolPPT;PPT
Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).
价 格:¥电议型 号:T16566产 地:中国大陆
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T16472Pericyazine;氰噻嗪Propericiazine|||RP 8909;Propericiazine|||氰噻嗪|||RP 8909
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psychosis.
价 格:¥电议型 号:T16472产 地:中国大陆
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T16466Penicillin G Procaine化合物 T16466PGP
Penicillin G Procaine is a β-lactam antibiotic and is a crystalline complex produced by chemically combining penicillin G with procaine.
价 格:¥电议型 号:T16466产 地:中国大陆
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T16464Pelubiprofen;化合物 T16464Pelubiprofen
Pelubiprofen, an orally active non-steroidal anti-inflammatory drug (NSAID) belonging to the 2-arylpropionic acid family, selectively inhibits COX-2 activity alongside COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway. It demonstrates significant anti-inflammatory and analgesic effects.
价 格:¥电议型 号:T16464产 地:中国大陆
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T1640Ciprofloxacin环丙沙星Ciproxan|||环丙沙星|||Ciprobay|||Bay o 9867|||Bay-09867
Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.
价 格:¥电议型 号:T1640产 地:中国大陆
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T16388Omidenepag isopropyl化合物 T16388Omidenepag isopropyl
Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl displays only a weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropyl is under development for the treatment of glaucoma as intraocular pressure (IOP)-lowering drug.
价 格:¥电议型 号:T16388产 地:中国大陆
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T16378Ogerin;化合物OgerinG Protein-Coupled Receptor 68|||Inhibitor|||TGF-β|||inhibit|||Ogerin|||fibroblasts||
Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor.
价 格:¥电议型 号:T16378产 地:中国大陆
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T16332NKH477;化合物 T16332Colforsin dapropate hydrochloride;Colforsin dapropate hydrochloride
NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts. NKH477 directly activates the catalytic unit of adenylate cyclase and enhances intracellular cAMP .
价 格:¥电议型 号:T16332产 地:中国大陆
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T1633β-Carotene;β-胡萝卜素Carotaben|||Beta-Carotene|||Provitamin A;beta-胡萝卜素|||Carotaben|||Beta-Carotene|||Pr
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA.
价 格:¥电议型 号:T1633产 地:中国大陆
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T16329Nitroflurbiprofen;硝基氟比洛芬NO-flurbiprofen|||Nitroxybutyl flurbiprofen|||HCT 1206;NO-flurbiprofen|||Nit
Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.
价 格:¥电议型 号:T16329产 地:中国大陆
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T16312NH2-PEG3;化合物 T16312PROTAC Linker 35;PROTAC Linker 35
NH2-PEG3 (PROTAC Linker 35) is a polyethylene glycol (PEG) linker utilized in the synthesis of PROTAC (β-NF-JQ1)[1].
价 格:¥电议型 号:T16312产 地:中国大陆
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T16300NH-bis(PEG2-propargyl);化合物 T16300NH-bis(PEG2-propargyl)
NH-bis(PEG2-propargyl) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16300产 地:中国大陆
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T1630Tiopronin硫普罗宁Thiopronine|||硫普罗宁|||Acadione|||Captimer
Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.
价 格:¥电议型 号:T1630产 地:中国大陆
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T16286Nelonemdaz;化合物 NelonemdazSalfaprodil free base|||Neu2000;Salfaprodil free base|||Neu2000
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
价 格:¥电议型 号:T16286产 地:中国大陆
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T16272Naproxen etemesil;化合物 T16272LT-NS 001|||MX 1094;LT-NS 001|||MX 1094
Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.
价 格:¥电议型 号:T16272产 地:中国大陆
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T16271Napropamide敌草胺敌草胺|||Napropamid
Napropamide is a selective systemic amide herbicide. Napropamide is used to control a number of annual grasses and broad-leaved weeds.
价 格:¥电议型 号:T16271产 地:中国大陆
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T1626Prostaglandin E1;前列地尔PGE1|||Alprostadil;前列地尔|||PGE1|||列腺素E1|||Alprostadil
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3´
价 格:¥电议型 号:T1626产 地:中国大陆
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T16252N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl);化合物 T16252N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative specifically designed as a linker for PROTAC synthesis [1].
价 格:¥电议型 号:T16252产 地:中国大陆
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T16250N-Succinimidyl 3-(Bromoacetamido)propionate;化合物 T162503-(2-Bromoacetamido)propanoic acid NHS ester;3
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker employed in the synthesis of PROTACs and antibody-drug conjugates (ADCs) [1, 2]. It acts as a cleavable ADC linker, facilitating the conjugation of drugs to antibodies for targeted delivery [2].
价 格:¥电议型 号:T16250产 地:中国大陆
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T16249N-(Propargyl-PEG4)-N-bis(PEG4-acid);化合物 T16249N-(Propargyl-PEG4)-N-bis(PEG4-acid)
N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively utilized in the synthesis of PROTACs (proteolysis targeting chimeras)[1].
价 格:¥电议型 号:T16249产 地:中国大陆