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T15884m-PEG4-propargyl;化合物 T15884m-PEG4-propargyl
m-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15884产 地:中国大陆
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T15863m-PEG3-Propanoyl chloride;化合物 T15863m-PEG3-Propanoyl chloride
m-PEG3-Propanoyl chloride is a polyethylene glycol (PEG)-derived linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T15863产 地:中国大陆
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T1582LNaproxen sodium;萘普生钠Miranax|||Anaprox|||RS-3650|||Naprelan;Miranax|||Anaprox|||RS-3650|||Naprelan|||
Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.
价 格:¥电议型 号:T1582L产 地:中国大陆
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T1582Naproxen;萘普生(S)-Naproxen;萘普生|||(S)-Naproxen
Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.
价 格:¥电议型 号:T1582产 地:中国大陆
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T15774Losmiprofen;氯米洛芬Losmiprofen
Losmiprofen is a nonsteroidal compound of antiinflammatory.
价 格:¥电议型 号:T15774产 地:中国大陆
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T1577Midodrine hydrochloride;盐酸米多君Pro-Amatine;Pro-Amatine|||盐酸米多君
Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine hydrochloride (Pro-Amatine) is the hydrochloride salt
价 格:¥电议型 号:T1577产 地:中国大陆
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T15757Limaprost;利马前列素17α,20-dimethyl-δ2-PGE1|||OP1206|||ONO1206;17α,20-dimethyl-δ2-PGE1|||利马前列素|||OP1206||
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost (17α,20-dimethyl-δ2-PGE1) can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.
价 格:¥电议型 号:T15757产 地:中国大陆
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T15743Levomepromazine;化合物 T15743Methotrimeprazine;Methotrimeprazine
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sites, including cholinergic, dopaminergic, serotonin, and histamine receptors.
价 格:¥电议型 号:T15743产 地:中国大陆
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T15719Latanoprostene bunod;化合物Latanoprostene bunodLBN|||NCX116;LBN|||NCX116
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT).
价 格:¥电议型 号:T15719产 地:中国大陆
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T15718Latanoprost acid;拉坦前列素游离酸Latanoprost acid
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
价 格:¥电议型 号:T15718产 地:中国大陆
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T15694L-Homopropargylglycine;化合物 T15694L-Homopropargylglycine
L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T15694产 地:中国大陆
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T1565Deferiprone;去铁酮Deferidone|||CP20;去铁酮|||Deferidone|||CP20
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
价 格:¥电议型 号:T1565产 地:中国大陆
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T1562Rebamipide;瑞巴派特Proamipide|||OPC12759;Proamipide|||OPC12759|||瑞巴派特
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulate
价 格:¥电议型 号:T1562产 地:中国大陆
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T1561Clobetasol propionate;丙酸氯倍他索Dermovate|||Clobetasol 17-propionate|||CGP9555|||Temovate|||CCl 4725;Der
Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clo
价 格:¥电议型 号:T1561产 地:中国大陆
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T15590Iodophenpropit dihydrobromide;化合物 T15590Iodophenpropit dihydrobromide
Iodophenpropit dihydrobromide is an effective and selective antagonist of the histamine H3 receptor. The binding of [125I]Iodophenpropit is readily reversible, selective, and of high affinity (KD: 0.32 nM).
价 格:¥电议型 号:T15590产 地:中国大陆
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T1559Betamethasone dipropionate;二丙酸倍他米松Diprolene AF|||SCH 11460|||Betamethasone 17,21-dipropionate|||Dipr
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in
价 格:¥电议型 号:T1559产 地:中国大陆
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T15585IRBP(668-687) (TFA);化合物 T15585Interphotoreceptor retinoid-binding protein(668-687) TFA;Interphotorec
Interphotoreceptor retinoid-binding protein TFA is the amino acid residue 668 to 687 of human interphotoreceptor retinoid-binding protein (IRBP). It also induces uveitis.
价 格:¥电议型 号:T15585产 地:中国大陆
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T15579INDY;化合物INDY1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one;1-(3-ethyl-5-hydroxy-1,3-be
INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.
价 格:¥电议型 号:T15579产 地:中国大陆
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T15573Inarigivir soproxil;化合物Inarigivir soproxilSB9200;SB9200
Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems).
价 格:¥电议型 号:T15573产 地:中国大陆
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T15560Iloprost;伊洛前列素ZK 36374|||Ciloprost;ZK 36374|||Ciloprost|||伊洛前列素
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost commonly employed in the treatment of peripheral vascular disease and also indicated in the treatment of patients affected by systemic sclerosis (SSc) in the presence of severe Raynaud´s phenomenon (RP).
价 格:¥电议型 号:T15560产 地:中国大陆