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  • T16477PF-03715455；化合物 T16477PF-03715455

    PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-03715455 has the potential for the treatment of COPD.

    价 格：￥电议型 号：T16477产 地：中国大陆

  • T16154MS417；化合物MS417GTPL7512；GTPL7512

    MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.

    价 格：￥电议型 号：T16154产 地：中国大陆

  • T15499HOOCCH2O-PEG4-CH2COOH；化合物 T15499HOOCCH2O-PEG4-CH2COOH

    HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.

    价 格：￥电议型 号：T15499产 地：中国大陆

  • T15498HOKU-81；化合物 T154984-Hydroxytulobuterol；4-Hydroxytulobuterol

    HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.

    价 格：￥电议型 号：T15498产 地：中国大陆

  • T15495HOE 32020；化合物 T15495HOE 32020

    HOE 32020 is a Hoechst stain, a blue fluorescent dyes, used to stain DNA. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 mg/mL. Aqueous solutions are stable at 2-6°C for at least six months when protected from light. For long-term storage the solutions are instead frozen at ≤-20°C.

    价 格：￥电议型 号：T15495产 地：中国大陆

  • T15494HO-PEG8-CH2CH2COOH；化合物 T15494Hydroxy-PEG8-acid；Hydroxy-PEG8-acid

    Hydroxy-PEG8-acid (HO-PEG8-CH2CH2COOH) is a PEG-based PROTAC linker employed for PROTAC synthesis[1].

    价 格：￥电议型 号：T15494产 地：中国大陆

  • T15493HO-PEG21-OH；化合物 T15493HO-PEG21-OH

    HO-PEG21-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15493产 地：中国大陆

  • T15492HO-PEG20-OH；化合物 T15492HO-PEG20-OH

    HO-PEG20-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15492产 地：中国大陆

  • T15491HO-PEG17-OH；化合物 T15491HO-PEG17-OH

    HO-PEG17-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15491产 地：中国大陆

  • T15490HO-PEG15-OH；化合物 T15490HO-PEG15-OH

    HO-PEG15-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15490产 地：中国大陆

  • T1549Raloxifene hydrochloride；盐酸雷洛昔芬LY156758 hydrochloride|||Raloxifene HCl|||LY139481 hydrochloride|||Ke

    Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.

    价 格：￥电议型 号：T1549产 地：中国大陆

  • T15489HO-PEG14-OH；化合物 T15489HO-PEG14-OH

    HO-PEG14-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15489产 地：中国大陆

  • T15488HO-PEG11-OH；化合物 T15488HO-PEG11-OH

    HO-PEG11-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T15488产 地：中国大陆

  • T15487HMR 1556化合物 T15487HMR1556|||HMR 1556|||HMR-1556

    HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).

    价 格：￥电议型 号：T15487产 地：中国大陆

  • T15486HLM006474；化合物HLM006474HLM006474

    HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).

    价 格：￥电议型 号：T15486产 地：中国大陆

  • T15485HJC0197；化合物HJC0197HJC0197

    HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).

    价 格：￥电议型 号：T15485产 地：中国大陆

  • T15483LEDGIN6；化合物 T15483HIV-1 integrase inhibitor 2；HIV-1 integrase inhibitor 2

    HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.

    价 格：￥电议型 号：T15483产 地：中国大陆

  • T15482HIF-2α-IN-1；HIF-2α抑制剂1HIF-2α-IN-1

    HIF-2α-IN-1 is a potent HIF-2α inhibitor with IC50 values less than 500 nM.

    价 格：￥电议型 号：T15482产 地：中国大陆

  • T15481HI-TOPK-032；化合物HI-TOPK-032HI-TOPK-032

    HI-TOPK-032 is an effective and specific inhibitor of TOPK.

    价 格：￥电议型 号：T15481产 地：中国大陆

  • T15480HG6-64-1；化合物 T15480HMSL 10017-101-1；HMSL 10017-101-1

    HG6-64-1 is a potent and selective inhibitor of B-Raf (IC50: 0.09 μM on B-raf V600E transformed Ba/F3 cells).

    价 格：￥电议型 号：T15480产 地：中国大陆

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