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T18870Vc-MMAD化合物Vc-MMADVc MMAD|||VcMMAD|||Vc-MMAD
Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs to deliver the cytotoxic agent MMAD specifically to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects.
价 格:¥电议型 号:T18870产 地:中国大陆
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T1887Inauhzin;化合物InauhzinINZ;INZ
Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
价 格:¥电议型 号:T1887产 地:中国大陆
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T18869Vat-Cit-PAB-Monomethyl Dolastatin 10;化合物 T18869Vat Cit PAB Monomethyl Dolastatin 10|||Vat-Cit-PAB-Mo
Vat-Cit-PAB-Monomethyl Dolastatin 10 is an ADC linker-conjugated drug designed to deliver potent antitumor activity. It achieves this through Monomethyl Dolastatin 10, a potent tubulin inhibitor, connected via the Vat-Cit-PAB ADC linker.
价 格:¥电议型 号:T18869产 地:中国大陆
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T18868Val-Cit;化合物Val-CitVal-Cit
Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18868产 地:中国大陆
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T18867Val-Cit-PAB-MMAE;化合物Val-Cit-PAB-MMAEDrug-Linker Conjugates for ADC|||inhibit|||Val-Cit-PAB-MMAE|||In
Val-Cit-PAB-MMAE is a?drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE?a potent?mitotic?inhibitor by inhibiting tubulin polymerization[1].
价 格:¥电议型 号:T18867产 地:中国大陆
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T18866UV Cleavable Biotin-PEG2-Azide;化合物 T18866UV Cleavable Biotin-PEG2-Azide
UV Cleavable Biotin-PEG2-Azide, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].
价 格:¥电议型 号:T18866产 地:中国大陆
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T18865Azide-phenylalanine hydrochloride;化合物 T18865UAA crosslinker 2;UAA crosslinker 2
UAA crosslinker 2 is a phenylalanine derivative.
价 格:¥电议型 号:T18865产 地:中国大陆
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T18864UAA crosslinker 1;化合物 T18864UAA crosslinker 1
UAA crosslinker 1 hydrochloride is an Amber codon-activating agent utilized for the incorporation of non-canonical amino acids (ncAAs) into proteins. This incorporation is achieved in vivo by leveraging the promiscuous activity of specific wildtype and engineered aminoacyl-tRNA synthetases[1].
价 格:¥电议型 号:T18864产 地:中国大陆
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T18863UAA crosslinker 1 hydrochloride;化合物 T18863UAA crosslinker 1 hydrochloride
UAA crosslinker 1 hydrochloride is an amber codon used to incorporate non-canonical amino acids (ncAAs) into proteins in vivo. This is achieved by leveraging the promiscuous activity of specific wildtype and engineered aminoacyl-tRNA synthetases[1].
价 格:¥电议型 号:T18863产 地:中国大陆
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T18862Triethylene glycol monobenzyl ether;化合物 T18862Triethylene glycol monobenzyl ether
Triethylene glycol monobenzyl ether, a PEG-derived PROTAC linker, facilitates the synthesis of PROTACs[1].
价 格:¥电议型 号:T18862产 地:中国大陆
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T18861Triethylene glycol bis(p-toluenesulfonate)化合物 T18861Bis-Tos-PEG3
Triethylene glycol bis(p-toluenesulfonate) is a polyethylene glycol (PEG) derived linker compound, utilized for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T18861产 地:中国大陆
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T18860Tri-(PEG1-C2-acid);化合物 T18860Tri-(PEG1-C2-acid)
Tri-(PEG1-C2-acid) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18860产 地:中国大陆
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T1885LSiramesine Fumarate;化合物 T1885LLU-28179|||LU-28-179|||LU 28 179;LU-28179|||LU-28-179|||LU 28 179
Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.
价 格:¥电议型 号:T1885L产 地:中国大陆
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T18859Tri(Mal-PEG2-amide)-amine;化合物 T18859Tri(Mal-PEG2-amide)-amine
Tri(Mal-PEG2-amide)-amine is a polyethylene glycol (PEG)-derived linker commonly employed for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18859产 地:中国大陆
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T18858Tri(Amino-PEG4-amide)-amine;化合物 T18858Tri(Amino-PEG4-amide)-amine
Tri(Amino-PEG4-amide)-amine is a polyethylene glycol (PEG)-based linker compound utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18858产 地:中国大陆
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T18857Tri(Amino-PEG3-amide)-amine;化合物 T18857Tri(Amino-PEG3-amide)-amine
Tri(Amino-PEG3-amide)-amine is a polyethylene glycol (PEG)-derived linker employed for the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].
价 格:¥电议型 号:T18857产 地:中国大陆
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T18856trans-Sulfo-SMCC;化合物 T18856trans-Sulfo-SMCC
trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.
价 格:¥电议型 号:T18856产 地:中国大陆
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T18855Tos-PEG9-Tos;化合物 T18855Tos-PEG9-Tos
Tos-PEG9-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18855产 地:中国大陆
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T18854Tos-PEG8-Tos;化合物 T18854Tos-PEG8-Tos
Tos-PEG8-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18854产 地:中国大陆