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T18816Thalidomide-O-amido-C6-NH2 hydrochloride;化合物T18816Thalidomide-O-amido-C6-NH2 hydrochloride
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, integrating a Thalidomide-based cereblon ligand with a linker, suitable for PROTAC synthesis.
价 格:¥电议型 号:T18816产 地:中国大陆
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T18815Thalidomide-O-amido-C4-NH2 hydrochloride;化合物 T18815Thalidomide-O-amido-C4-NH2 hydrochloride
Thalidomide-O-amido-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker. It is commonly employed in the synthesis of PROTACs[1].
价 格:¥电议型 号:T18815产 地:中国大陆
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T18814Thalidomide-NH-PEG7;化合物 T18814Thalidomide-NH-PEG7
Thalidomide-NH-PEG7 is a synthesized conjugate of an E3 ligase ligand and linker designed for use in antibody-drug conjugates (ADCs). This compound can be coupled to a protein ligand via a linker to create PROTAC iRucaparib-AP6, an extremely selective degrader of PARP1[1].
价 格:¥电议型 号:T18814产 地:中国大陆
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T18813Thalidomide-PEG2-C2-NH2;化合物 T18813Thalidomide-NH-PEG2-C2-NH2;Thalidomide-NH-PEG2-C2-NH2
Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
价 格:¥电议型 号:T18813产 地:中国大陆
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T18812Thalidomide-PEG2-C2-NH2 TFA;化合物 T18812Thalidomide-NH-PEG2-C2-NH2 TFA;Thalidomide-NH-PEG2-C2-NH2 TFA
Thalidomide-O-amido-PEG3-C2-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand based on Thalidomide and a 2-unit PEG linker for use in PROTAC technology[1].
价 格:¥电议型 号:T18812产 地:中国大陆
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T18811Thalidomide-PEG2-C2-NH2 hydrochloride;化合物 T18811Thalidomide-NH-PEG2-C2-NH2 hydrochloride;Thalidomide
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, combines a Thalidomide-based cereblon ligand with a two-unit PEG linker for use in PROTAC technology[1].
价 格:¥电议型 号:T18811产 地:中国大陆
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T18810Thalidomide-NH-C6-NH2;化合物 T18810Thalidomide-NH-C6-NH2
Thalidomide-NH-C6-NH2 is a synthetic conjugate compound designed as an E3 ligase ligand-linker. It consists of a Thalidomide-based cereblon ligand linked to a specific linker utilized in PROTAC technology[1].
价 格:¥电议型 号:T18810产 地:中国大陆
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T1881AR-A014418;化合物AR-A014418AR 0133418|||GSK-3beta Inhibitor VIII|||AR 014418|||GSK 3β inhibitor VIII;AR
AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.
价 格:¥电议型 号:T1881产 地:中国大陆
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T18809Thalidomide-NH-C6-NH2 TFA;化合物 T18809Thalidomide-NH-C6-NH2 TFA
Thalidomide-NH-C6-NH2 TFA is a synthetic conjugate compound that combines a cereblon ligand based on Thalidomide with a linker used in PROTAC technology, functioning as an E3 ligase ligand-linker conjugate[1].
价 格:¥电议型 号:T18809产 地:中国大陆
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T18808Thalidomide-NH-C4-NH2 TFA;化合物 T18808Thalidomide-NH-C4-NH2 TFA
Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate consisting of an E3 ligase ligand-linker, incorporating the Thalidomide-based cereblon ligand and a linker moiety. This compound, Thalidomide-NH-C4-NH2 TFA, is utilized as a component in PROTAC BRD2/BRD4 degrader-1, which is a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1].
价 格:¥电议型 号:T18808产 地:中国大陆
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T18807Thalidomide-NH-C4-NH-Boc;化合物Thalidomide-NH-C4-NH-BocThalidomide-NH-C4-NH-Boc
Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.
价 格:¥电议型 号:T18807产 地:中国大陆
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T18806Thalidomide-NH-C10-COOH;化合物 T18806Thalidomide-NH-C10-COOH
Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) ligand with a linker commonly employed in PROTAC technology. [1]
价 格:¥电议型 号:T18806产 地:中国大陆
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T18805Thalidomide-C2-amido-C2-COOH;化合物 T18805Thalidomide-C2-amido-C2-COOH
Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of PROTAC CDK2/9 Degrader-1[1].
价 格:¥电议型 号:T18805产 地:中国大陆
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T18804Tetrazine-SS-PEG4-Biotin;化合物 T18804Tetrazine-SS-PEG4-Biotin
Tetrazine-SS-PEG4-Biotin, a cleavable 4-unit PEG ADC linker, is employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18804产 地:中国大陆
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T18803Tetrazine-SS-NHS;化合物 T18803Tetrazine-SS-NHS
Tetrazine-SS-NHS is a cleavable linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18803产 地:中国大陆
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T18802Tetrazine-SS-Biotin;化合物 T18802Tetrazine-SS-Biotin
Tetrazine-SS-Biotin, a cleavable ADC linker, finds utility in ADC (antibody-drug conjugate) synthesis [1].
价 格:¥电议型 号:T18802产 地:中国大陆
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T18801Tetrazine-Ph-PEG5-Ph-tetrazine;化合物 T18801Tetrazine-Ph-PEG5-Ph-tetrazine
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T18801产 地:中国大陆
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T18800Tetrazine-Ph-PEG4-Ph-aldehyde;化合物 T18800Tetrazine-Ph-PEG4-Ph-aldehyde
Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18800产 地:中国大陆
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T1880P7C3;化合物P7C3P7C3
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain injury (TBI). This protective quality may be linked to the ability of P7C3 molecules to activate nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in nicotinamide adenine dinucleot
价 格:¥电议型 号:T1880产 地:中国大陆
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T18188m-PEG3-Sulfone-PEG3;化合物 T18188m-PEG3-Sulfone-PEG3
m-PEG3-Sulfone-PEG3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18188产 地:中国大陆