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T6571Lomerizine dihydrochloride;盐酸洛美利嗪Terranas|||Lomerizine 2HCl|||Lomerizine hydrochloride|||KB-2796;Ter
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
价 格:¥电议型 号:T6571产 地:中国大陆
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T6568211-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride;化合物 11-(1-Piperazinyl)-dibenzo[b,f][1
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65682 and the CAS number is 111974-74-4.
价 格:¥电议型 号:T65682产 地:中国大陆
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T6562Latrepirdine dihydrochloride;化合物LatrepirdineDimebolin dihydrochloride|||Latrepirdine|||Latrepirdine
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
价 格:¥电议型 号:T6562产 地:中国大陆
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T65526(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride;化合物 (3S,4S)-1-Benzyl-N,4-dimethylpipe
(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65526 and the CAS number is 1354486-07-9.
价 格:¥电议型 号:T65526产 地:中国大陆
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T6534Histamine dihydrochloride;组胺二盐酸盐peremin|||Ceplene|||Histamine 2HCl;组胺二盐酸盐|||peremin|||Ceplene|||Hist
Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
价 格:¥电议型 号:T6534产 地:中国大陆
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T65138DL-Lysine dihydrochloride;化合物 DL-Lysine dihydrochlorideDL-Lysine dihydrochloride
DL-Lysine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65138 and the CAS number is 617-68-5.
价 格:¥电议型 号:T65138产 地:中国大陆
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T649402-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol dihydrochloride;化合物 2-(4-((4-Chloropheny
2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64940 and the CAS number is 164726-80-1.
价 格:¥电议型 号:T64940产 地:中国大陆
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T645184-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinoxalin-2-one dihydrochloride;化合物 4-(Piperidin-4-yl)-1,2,3,4
4-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinoxalin-2-one dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64518.
价 格:¥电议型 号:T64518产 地:中国大陆
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T6426Buclizine dihydrochloride;盐酸安其敏Longifene|||Buclina|||Buclizine HCl|||UCB-4445;盐酸安其敏|||Longifene|||Bu
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine dihydrochloride exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system
价 格:¥电议型 号:T6426产 地:中国大陆
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T6423BRL-15572 dihydrochloride;四氢罂粟碱盐酸盐BRL 15573 dihydrochloride;四氢罂粟碱盐酸盐|||BRL 15573 dihydrochloride
BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
价 格:¥电议型 号:T6423产 地:中国大陆
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T64151Mibefradil dihydrochloride hydrate;化合物 Mibefradil dihydrochloride hydrateMibefradil dihydrochloride
Mibefradil dihydrochloride hydrate (Ro 40-5967 dihydrochloride hydrate) is a long-acting calcium channel antagonist. Mibefradil dihydrochloride hydrate is an antihypertensive agent that acts with a higher affinity for high voltage activated (L) calcium channels.
价 格:¥电议型 号:T64151产 地:中国大陆
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T64150CX-5461 dihydrochloride;化合物 CX-5461 dihydrochlorideCX-5461 dihydrochloride
CX-5461 dihydrochloride is a potent, orally active inhibitor of Pol I-mediated rRNA synthesis that acts on HCT-116 cells (IC50: 142 nM), A375 cells (IC50: 113 nM) and MIA PaCa-2 cells (IC50: 54 nM), and to a lesser extent on Pol II (IC50 ≥ 25 μM).
价 格:¥电议型 号:T64150产 地:中国大陆
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T64055SPOP-IN-6b dihydrochloride;化合物 SPOP-IN-6b dihydrochlorideSPOP-IN-6b dihydrochloride
SPOP-IN-6b dihydrochloride is a potent inhibitor of spotted POZ protein (SPOP) (IC50: 3.58 μM).
价 格:¥电议型 号:T64055产 地:中国大陆
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T63984PF-3758309 dihydrochloride;化合物 PF-3758309 dihydrochloridePF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent, reversible, orally active, ATP-competitive PAK4 inhibitor with a Kd value of 2.7 nM and a Ki value of 18.7 nM. PF-3758309 dihydrochloride exhibits the expected cellular functions of a PAK4 inhibitor, with the ability to inhibit anchorage independent growth, induction of apoptosis, cytoskeletal remodelling and inhibition of proliferation.
价 格:¥电议型 号:T63984产 地:中国大陆
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T63762AMG-548 dihydrochloride;化合物 AMG-548 dihydrochlorideAMG-548 dihydrochloride
AMG-548 dihydrochloride is a selective, orally active p38α inhibitor with a Ki value of 0.5 nM, a slight selectivity for p38β (Ki=36 nM) and >1000-fold selectivity for p38γ and p38δ. AMG-548 dihydrochloride exhibits inhibition of whole blood LPS-stimulated TNFα with an IC50 value of 3 nM. AMG-548 dihydrochloride directly inhibited casein kinase 1 isoforms δ and ε, and inhibited Wnt signaling.
价 格:¥电议型 号:T63762产 地:中国大陆
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T63634Palbociclib dihydrochloride;化合物 Palbociclib dihydrochloridePalbociclib dihydrochloride
Palbociclib (PD 0332991) dihydrochloride is an orally active, selective inhibitor of CDK4 (IC50: 11 nM) and CDK6 (IC50: 16 nM). Palbociclib dihydrochloride has anti-proliferative activity and cell cycle arrest in HR-positive and HER2-negative breast cancers, as well as in hepatocellular carcinoma studies.
价 格:¥电议型 号:T63634产 地:中国大陆
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T63630Gefitinib dihydrochloride;化合物 Gefitinib dihydrochlorideGefitinib dihydrochloride
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib dihydrochloride induces autophagy and apoptosis, and can be used in studies of cancer-related diseases such as lung and breast cancer.
价 格:¥电议型 号:T63630产 地:中国大陆
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T63550(1S,3R,5R)-PIM447 dihydrochloride;化合物 (1S,3R,5R)-PIM447 dihydrochloride(1S,3R,5R)-PIM447 dihydrochlo
(1S,3R,5R)-PIM447 (dihydrochloride) is an inhibitor of PIM, capable of Pim1 (IC50: 0.095 μM), Pim2 (IC50: 0.522 μM) and Pim3 (IC50: 0.369 μM).
价 格:¥电议型 号:T63550产 地:中国大陆
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T63506Chroman 1 dihydrochloride;化合物 Chroman 1 dihydrochlorideChroman 1 dihydrochloride
Chroman 1 dihydrochloride is a selective and potent inhibitor of ROCK, acting more strongly on ROCK2 (IC50: 1 pM) than ROCK1 (IC50: 52 pM) and also inhibiting MRCK activity (IC50: 150 nM).
价 格:¥电议型 号:T63506产 地:中国大陆
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T63180CARM1-IN-3 dihydrochloride;化合物 CARM1-IN-3 dihydrochlorideCARM1-IN-3 dihydrochloride
CARM1-IN-3 dihydrochloride (compound 17b) CARM1-IN-3 dihydrochloride (compound 17b) is a potent, selective coactivator-associated arginine methyltransferase (CARM1) inhibitor that acts on CARM1 (IC50: 0.07 μM) and CARM3 ( IC50>25 μM).
价 格:¥电议型 号:T63180产 地:中国大陆