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T63115Perphenazine dihydrochloride；化合物 Perphenazine dihydrochloridePerphenazine dihydrochloride
Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), 5-HT2A (Ki: 0.6 nM). Perphenazine dihydrochloride is also able to bind Alpha-1A adrenergic receptors. Perphenazine dihydrochloride can induce apoptosis and inhibit the proliferation of cancer cells. Perphenazine dihydrochloride can be used to study psychiatric disorders, cancer, and inflammation.
价 格：￥电议型 号：T63115产 地：中国大陆
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T63004NUCC-390 dihydrochloride；化合物 NUCC-390 dihydrochlorideNUCC-390 dihydrochloride
NUCC-390 dihydrochloride, a novel and selective CXCR4 receptor agonist, effectively induces the internalization of CXCR4 receptors and acts antagonistically to AMD3100 [1]. This small-molecule compound has demonstrated the ability to facilitate functional nerve recovery following neurodegeneration in vivo [2].
价 格：￥电议型 号：T63004产 地：中国大陆
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T6294NVP-BSK805 2HCl (1092499-93-8(free base))；化合物NVP-BSK805 2HClNVP-BSK805 dihydrochloride|||BSK 805|||N
NVP-BSK805 2HCl (1092499-93-8(free base)) (BSK 805)(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格：￥电议型 号：T6294产 地：中国大陆
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T62878Zalunfiban dihydrochloride；化合物 Zalunfiban dihydrochlorideZalunfiban dihydrochloride
Zalunfiban (RUC-4) dihydrochloride is a selective and potent platelet αIIbβ3 antagonist with an IC50 value of 45 nM. Zalunfiban dihydrochloride can be used to study myocardial infarction.
价 格：￥电议型 号：T62878产 地：中国大陆
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T62774BS-181 dihydrochloride；化合物 BS-181 dihydrochlorideBS-181 dihydrochloride
BS-181 dihydrochloride is a selective and potent inhibitor of CDK7 with an IC50 value of 21 nM. BS-181 dihydrochloride inhibits CDK2 (IC50: 880 nM), CDK5 (IC50: 3000 nM) and CDK9 (IC50: 4200 nM), but does not block CDK1, 4 and 6. BS-181 dihydrochloride inhibits the growth of a group of cancer cells (IC50: 11.5 μM-37.3 μM) and induces apoptosis.
价 格：￥电议型 号：T62774产 地：中国大陆
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T62735GDC-0575 dihydrochloride；化合物 GDC-0575 dihydrochlorideGDC-0575 dihydrochloride
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is a selective, orally active CHK1 inhibitor (IC50: 1.2 nM) that exhibits antitumour effects.
价 格：￥电议型 号：T62735产 地：中国大陆
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T62691Syk Inhibitor II dihydrochloride dihydrate；化合物 Syk Inhibitor II dihydrochloride dihydrateSyk Inhibit
Syk Inhibitor II dihydrochloride dihydrate is a highly selective, potent, ATP-competitive Syk inhibitor (IC50: 41 nM). Syk Inhibitor II dihydrochloride dihydrate exhibits anti-allergic effects.
价 格：￥电议型 号：T62691产 地：中国大陆
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T62520Imidocarb dihydrochloride monohydrate；化合物 Imidocarb dihydrochloride monohydrateImidocarb dihydrochlo
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).
价 格：￥电议型 号：T62520产 地：中国大陆
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T625063,6-DMAD dihydrochloride；化合物 3,6-DMAD dihydrochloride3,6-DMAD dihydrochloride
3,6-DMAD dihydrochloride is an acridine derivative and a potent inhibitor of the IRE1α-XBP1s pathway. 3,6-DMAD dihydrochloride can induce IL-6 secretion by exploiting the IRE1α-XBP1s pathway. 3,6-DMAD dihydrochloride is a potent inhibitor of the IRE1α-XBP1s pathway. 3,6-DMAD dihydrochloride has inhibitory effects on IRE1α oligomerization and RNase activity. 3,6-DMAD dihydrochloride can be used in cancer research.
价 格：￥电议型 号：T62506产 地：中国大陆
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T6250H-89 dihydrochloride；化合物H 89 2HClProtein kinase inhibitor H-89 dihydrochloride|||H 89 2HCl|||5-Isoqu
H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).
价 格：￥电议型 号：T6250产 地：中国大陆
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T62424L-Moses dihydrochloride；化合物 L-Moses dihydrochlorideL-Moses dihydrochloride
L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).
价 格：￥电议型 号：T62424产 地：中国大陆
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T62388RUSKI-201 dihydrochloride；化合物 RUSKI-201 dihydrochlorideRUSKI-201 dihydrochloride
RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 μM). RUSKI-201 dihydrochloride blocks Hh signalling in Shh overexpressing cells and has an inhibitory effect on Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe that can be used to study Hhat catalytic function.
价 格：￥电议型 号：T62388产 地：中国大陆
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T62011LDN-209929 dihydrochloride；化合物 LDN-209929 dihydrochlorideLDN-209929 dihydrochloride
LDN-209929 dihydrochloride is a potent and selective inhibitor of haspin kinase (IC50= 55 nM). LDN-209929 dihydrochloride shows180-fold selectivity verses DYRK2 (IC50= 9.9 μM).
价 格：￥电议型 号：T62011产 地：中国大陆
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T61905RKI-1447 dihydrochloride；化合物 RKI-1447 dihydrochlorideRKI-1447 dihydrochloride
RKI 1447 dihydrochloride is an effective and selective ROCK inhibitor (ROCK1 IC50=14.5 nM, ROCK2 IC50=6.2 nM). RKI 1447 dihydrochloride can inhibit the growth of colorectal cancer cells and promote cell apoptosis.
价 格：￥电议型 号：T61905产 地：中国大陆
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T61741Azaphen dihydrochloride monohydrate；化合物 Azaphen dihydrochloride monohydrateAzaphen dihydrochloride m
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIs Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to its antidepressant action, pipofezine has sedative effects as well, indicating antihistamine activity.
价 格：￥电议型 号：T61741产 地：中国大陆
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T61479LOX-IN-3 dihydrochloride monohydrate；化合物 LOX-IN-3 dihydrochloride monohydrateLOX-IN-3 dihydrochlorid
LOX-IN-3 dihydrochloride monohydrate (Compound 33) is a lysyl oxidase (LOX) inhibitor with oral activity. It is specifically designed for research purposes in the areas of fibrosis, cancer, and angiogenesis [1].
价 格：￥电议型 号：T61479产 地：中国大陆
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T6146Dorsomorphin dihydrochloride；化合物Dorsomorphin dihydrochlorideBML-275 2HCl|||Compound C dihydrochlorid
Dorsomorphin dihydrochloride (BML-275 2HCl) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin dihydrochloride inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy, and possesses antitumor activity.
价 格：￥电议型 号：T6146产 地：中国大陆
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T61382Fasudil dihydrochloride；化合物 Fasudil dihydrochlorideFasudil dihydrochloride
Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA/ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 μM, as well as ROCK2, PKA, PKC, and PKG with IC 50 values of 0.158 μM, 4.58 μM, 12.30 μM, and 1.650 μM, respectively. Additionally, Fasudil dihydrochloride demonstrates potent Ca 2+ channel blocking activity and acts as a vasodilator [1] [2] [3].
价 格：￥电议型 号：T61382产 地：中国大陆
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T61338MS023 dihydrochloride；MS023 盐酸盐MS023 2HCl；MS023 2HCl
MS023 dihydrochloride (MS023 2HCl) is a selective, cytosolic and highly potent inhibitor of human type I protein arginine methyltransferases (PRMTs) with antitumour activity, inhibits PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, and increases the proliferative capacity of isolated cultured MuSC. It can be used to study breast cancer.
价 格：￥电议型 号：T61338产 地：中国大陆
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T61336Numidargistat dihydrochloride；化合物 Numidargistat dihydrochlorideNumidargistat dihydrochloride
Numidargistat dihydrochloride (CB-1158) is a highly potent and orally active chemical compound that effectively inhibits arginase. It exhibits IC50 values of 86 nM and 296 nM for recombinant human arginase 1 and 2, respectively. Numidargistat dihydrochloride contributes to immuno-oncology, making it a valuable agent in the field [1].
价 格：￥电议型 号：T61336产 地：中国大陆
