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T16962SW-100;化合物SW-100SW-100
SW-100 is a selective histone deacetylase 6 inhibitor (IC50: 2.3 nM). It also shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays an obviously improved ability to cross the blood-brain-barrier.
价 格:¥电议型 号:T16962产 地:中国大陆
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T16862SCH-1473759;化合物 T16862SCH-1473759
SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).
价 格:¥电议型 号:T16862产 地:中国大陆
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T16799RS-246204;化合物 T16799RS-246204
RS-246204 is an R-spondin-1 substitute compound. RS-246204 is able to initiate small intestinal organoids without the use of the R-spondin-1 protein.
价 格:¥电议型 号:T16799产 地:中国大陆
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T16762RMC-4550;化合物RMC-4550RMC-4550
RMC-4550 is an effective and allosteric inhibitor of SHP2 (IC50: 0.583 nM).
价 格:¥电议型 号:T16762产 地:中国大陆
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T1667Tandutinib;坦度替尼MLN518|||CT53518|||NSC726292;MLN518|||CT53518|||NSC726292|||坦度替尼
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
价 格:¥电议型 号:T1667产 地:中国大陆
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T16662Tetraethylene glycol三缩四乙二醇PROTAC Linker 18|||三缩四乙二醇
Tetraethylene glycol (PROTAC Linker 18) is a polyethylene glycol (PEG)-based linker that finds utility in the synthesis of PROTACs[1].
价 格:¥电议型 号:T16662产 地:中国大陆
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T16629Propargyl-PEG4-O-C1-Boc;化合物 T16629Propargyl-PEG4-O-C1-Boc
Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16629产 地:中国大陆
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T16628Propargyl-PEG4-NHS ester;化合物 T16628Propargyl-PEG4-NHS ester
Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
价 格:¥电议型 号:T16628产 地:中国大陆
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T16627Propargyl-PEG4-methylamine;化合物 T16627Propargyl-PEG4-methylamine
Propargyl-PEG4-methylamine is a polyethylene glycol (PEG) derived linker essential for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T16627产 地:中国大陆
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T16626Propargyl-PEG3-methane;化合物 T16626Propargyl-PEG3-methane
Propargyl-PEG3-methane is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16626产 地:中国大陆
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T16625Propargyl-PEG4-CH2COOH;化合物 T16625Propargyl-PEG4-CH2COOH
Propargyl-PEG4-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16625产 地:中国大陆
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T16624Propargyl-PEG4-CH2CH2-Boc;化合物 T16624Propargyl-PEG4-CH2CH2-Boc
Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
价 格:¥电议型 号:T16624产 地:中国大陆
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T16621Propargyl-PEG5-NHS ester;化合物 T16621Propargyl-PEG5-NHS ester
Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16621产 地:中国大陆
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T16620Propargyl-PEG5-acid;化合物 T16620Propargyl-PEG4-C2-acid;Propargyl-PEG4-C2-acid
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1].
价 格:¥电议型 号:T16620产 地:中国大陆
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T16625-Aminolevulinic acid hydrochloride;5-氨基乙酰丙酸盐酸盐Hydrangin|||5-ALA|||5-Aminolevulinic acid HCl|||ALA h
5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body´s heme biosynthesis and is the universal precursor of tetrapyrroles.
价 格:¥电议型 号:T1662产 地:中国大陆
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T16562Ponceau 4R胭脂红Acid Red 18|||New Coccine
Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usually synthesized from aromatic hydrocarbons.
价 格:¥电议型 号:T16562产 地:中国大陆
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T16511PF2562;化合物 T16511PF2562
PF2562 is a dopamine D1 ligand. It is used as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor (Ki: 113 nM). PF2562 shows activity against human D1 cAMP (EC50: 568 nM in HTRF assay).
价 格:¥电议型 号:T16511产 地:中国大陆
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T16504PF-4693627;化合物 T16504PF-4693627
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).
价 格:¥电议型 号:T16504产 地:中国大陆
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T16488PF-06263276;化合物 T16488PF-06263276
PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
价 格:¥电议型 号:T16488产 地:中国大陆
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T16475Pexacerfont化合物PexacerfontBMS-562086
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
价 格:¥电议型 号:T16475产 地:中国大陆