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T16462PEG5-Tos;化合物 T16462PEG5-Tos
PEG5-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16462产 地:中国大陆
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T16449PD176252;化合物PD176252PD176252
PD176252 is a potent BB1 and BB2 antagonist with inhibitory effects on BB1 and BB2 receptors.PD176252 acts as a small molecule GRPR inhibitor and FPR1/FPR2 agonist to inhibit the growth and proliferation of a variety of cancer cells.
价 格:¥电议型 号:T16449产 地:中国大陆
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T16401Org-12962;化合物Org-12962Org-12962
Org-12962 is an effective and selective 5-HT2C?receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A?and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively).
价 格:¥电议型 号:T16401产 地:中国大陆
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T16387Ombrabulin;化合物 T16387AVE8062|||AC7700;AVE8062|||AC7700
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.
价 格:¥电议型 号:T16387产 地:中国大陆
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T16386Ombrabulin hydrochloride化合物 T16386AVE8062 (hydrochloride)|||AC7700 (hydrochloride)
Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and has antivascular effects. Ombrabulin is a tubulin polymerizing inhibitor, a member of the combretastatin A-4 compound class, which is a water-soluble tubulin depolymerizing tumor vascularizing compound.
价 格:¥电议型 号:T16386产 地:中国大陆
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T16362Nuvenzepine;化合物 T16362Nuvenzepine
Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.
价 格:¥电议型 号:T16362产 地:中国大陆
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T16353Meseclazone;美西拉宗W2395|||NSC297623;美西拉宗|||W2395|||NSC297623
Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.
价 格:¥电议型 号:T16353产 地:中国大陆
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T16347NS3623;化合物NS3623NS3623
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic effect.
价 格:¥电议型 号:T16347产 地:中国大陆
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T16330Nitromifene;化合物 T16330CI628;CI628
Nitromifene is the estrogen receptor antagonist.
价 格:¥电议型 号:T16330产 地:中国大陆
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T16299NH-bis(PEG2-C2-Boc);化合物 T16299NH-bis(PEG2-C2-Boc)
NH-bis(PEG2-C2-Boc) is an alkyl/ether-based linker, utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T16299产 地:中国大陆
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T16298NH-bis(m-PEG8);化合物 T16298NH-bis(m-PEG8)
NH-bis(m-PEG8) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16298产 地:中国大陆
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T16297NH-bis(m-PEG4);化合物 T16297NH-bis(m-PEG4)
NH-bis(m-PEG4) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16297产 地:中国大陆
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T16296NH-bis(C2-PEG2-NH-Boc);化合物 T16296NH-bis(C2-PEG2-NH-Boc)
NH-bis(C2-PEG2-NH-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16296产 地:中国大陆
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T16295NH-bis(C2-PEG1-azide);化合物 T16295NH-bis(C2-PEG1-azide)
NH-bis(C2-PEG1-azide) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16295产 地:中国大陆
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T16293NGD-4715;化合物 T16293NGD-4715
NGD-4715 is a selective and orally active antagonist of melanin-concentrating hormone receptor 1.
价 格:¥电议型 号:T16293产 地:中国大陆
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T16292NFPS;化合物 T16292NFPS
NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion. NFPS is a selective and non-competitive glycine transporter-1 (GlyT1) inhibitor (IC50s: 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively).
价 格:¥电议型 号:T16292产 地:中国大陆
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T16291NF157;化合物 T16291NF157
NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly selective nanomolar P2Y11 antagonist (pKi: 7.35). The IC50s are 463 nM, 1811 μM, 170 μM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 μM), P2Y2 (Ki=28.9 μM), respectively.
价 格:¥电议型 号:T16291产 地:中国大陆
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T16290NIK SMI1;化合物NIK SMI1NIK SMI1
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).
价 格:¥电议型 号:T16290产 地:中国大陆
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T1629Rifapentine;利福喷丁MDL473|||Rifapentina|||Rifapentinum|||DL 473|||Priftin|||Cyclopentylrifampicin;MDL47
Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.
价 格:¥电议型 号:T1629产 地:中国大陆