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T16167N-(4-Carboxycyclohexylmethyl)maleimide；化合物 T16167N-(4-Carboxycyclohexylmethyl)maleimide
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker suitable for synthesizing PROTACs[1].
价 格：￥电议型 号：T16167产 地：中国大陆
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T16166N-[(4-Aminophenyl)methyl]adenosine；N-[(4-氨基苯基)甲基]腺苷N-[(4-Aminophenyl)methyl]adenosine
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
价 格：￥电议型 号：T16166产 地：中国大陆
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T16165Myriocin多球壳菌素ISP-I|||Thermozymocidin
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour growth by regulating macrophage polarisation and function through the PI3K/Akt/mTOR pathway.Myriocin inhibits HCV infection and can be used in the study of neurological diseases. Myriocin inhibits HCV infection and can be used to study neuropathy and fungal infections.
价 格：￥电议型 号：T16165产 地：中国大陆
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T16164MY-5445；化合物MY-5445N-(3-chlorophenyl)-4-phenylphthalazin-1-amine；N-(3-chlorophenyl)-4-phenylphthalazi
MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).
价 格：￥电议型 号：T16164产 地：中国大陆
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T16163MV1；化合物MV1MV1
MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.
价 格：￥电议型 号：T16163产 地：中国大陆
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T16162Mutated EGFR-IN-1；AZD9291中间体1Osimertinib analog；Osimertinib analog|||AZD9291中间体1
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
价 格：￥电议型 号：T16162产 地：中国大陆
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T16161Mutant IDH1 inhibitor；化合物Mutant IDH1 inhibitorMutant IDH1 inhibitor
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
价 格：￥电议型 号：T16161产 地：中国大陆
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T16160Musk tibetene；化合物 T16160Musk tibetine；Musk tibetine
Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell lines. Musk tibetene is a nitro musk compound with carcinogenic activity.
价 格：￥电议型 号：T16160产 地：中国大陆
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T1616Cefotiam hydrochloride；盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
价 格：￥电议型 号：T1616产 地：中国大陆
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T1615LIrbesartan HCl；化合物 T1615LIrbesartan hydrochloride|||BMS186295|||BMS 186295|||BMS-186295；Irbesartan h
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor.
价 格：￥电议型 号：T1615L产 地：中国大陆
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T16159Muramyl dipeptide；佐剂肽MDP；MDP
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation through a decreased RANKL/OPG ratio. Muramyl dipeptide directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is an inducer of bone formation through the induction of Runx2 .
价 格：￥电议型 号：T16159产 地：中国大陆
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T16158PF-02575799；化合物 T16158PF-02575799
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
价 格：￥电议型 号：T16158产 地：中国大陆
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T16157MT-802；化合物MT-802MT-802
MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL).
价 格：￥电议型 号：T16157产 地：中国大陆
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T16156MT 63-78；化合物MT 63-78MT 63-78
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cell mitotic arrest and apoptosis.
价 格：￥电议型 号：T16156产 地：中国大陆
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T16155MSN-125；化合物 T16155MSN-125
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) (IC50: 4 μM).
价 格：￥电议型 号：T16155产 地：中国大陆
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T16154MS417；化合物MS417GTPL7512；GTPL7512
MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.
价 格：￥电议型 号：T16154产 地：中国大陆
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T16153MS4078；化合物MS4078MS4078
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19?nM for binding affinity to ALK.
价 格：￥电议型 号：T16153产 地：中国大陆
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T16152Betamethasone 17-benzoate；苯甲酸倍他米松Betamethasone 17-benzoate
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
价 格：￥电议型 号：T16152产 地：中国大陆
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T16151Ms-PEG7-Ms；化合物 T16151Ms-PEG7-Ms
Ms-PEG7-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16151产 地：中国大陆
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T16150Ms-PEG5-t-butyl ester；化合物 T16150Ms-PEG4-t-butyl ester；Ms-PEG4-t-butyl ester
Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16150产 地：中国大陆
