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T4664ML 297;化合物ML297ML297;ML297
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
价 格:¥电议型 号:T4664产 地:中国大陆
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T4619ML-098;化合物ML-098CID-7345532;CID-7345532
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
价 格:¥电议型 号:T4619产 地:中国大陆
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T4540ML-18;化合物ML 18ML-18
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.
价 格:¥电议型 号:T4540产 地:中国大陆
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T4399ML239;化合物ML239CID-49843203;CID-49843203
ML239 (CID-49843203) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.
价 格:¥电议型 号:T4399产 地:中国大陆
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T4390ML221;化合物ML221ML221
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
价 格:¥电议型 号:T4390产 地:中国大陆
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T4360ML385;化合物ML385ML385
ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity.
价 格:¥电议型 号:T4360产 地:中国大陆
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T4347ML355;化合物ML355ML355
ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
价 格:¥电议型 号:T4347产 地:中国大陆
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T4316ML365;化合物ML365ML365
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
价 格:¥电议型 号:T4316产 地:中国大陆
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T4284Levamlodipine besylate;左旋氨氯地平(S)-Amlodipine Besylate (103129-82-4(free base));左旋氨氯地平|||(S)-Amlodipin
Levamlodipine besylate ((S)-Amlodipine Besylate (103129-82-4(free base))) , also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipine besylate belongs to the dihydropyridine group of calcium channel blockers. The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however, with differing nomenclature. As a racemic mixture, amlodipine contains (R) and (S)-amlodipi
价 格:¥电议型 号:T4284产 地:中国大陆
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T4252ML327;化合物ML327ML327
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
价 格:¥电议型 号:T4252产 地:中国大陆
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T4224ML335;化合物ML335ML335
ML335 is a selective activator of TREK-1 and TREK-2.
价 格:¥电议型 号:T4224产 地:中国大陆
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T41027MLKL-IN-2;MLKL抑制剂2MLKL-IN-2
MLKL-IN-2 is an MLKL inhibitor with potential tumorigenic activity for the study of cellular necrosis-related diseases.
价 格:¥电议型 号:T41027产 地:中国大陆
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T41014MLS1082;MLS1082MLS1082
MLS1082 is a pyrimidone-derived compound that acts as a positive allosteric modulator of D1-like dopamine receptors. It exhibits an EC 50 value of 123 nM for stimulating G protein signaling in response to dopamine activation.
价 格:¥电议型 号:T41014产 地:中国大陆
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T40968MLS-0437605;MLS-0437605MLS-0437605
MLS-0437605 is a potent and selective inhibitor of dual-specificity phosphatase 3 (DUSP3), with an IC50 of 3.7 μM. It exhibits higher selectivity towards DUSP3 in comparison to DUSP22 and other protein tyrosine phosphatases (PTPs).
价 格:¥电议型 号:T40968产 地:中国大陆
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T4084Sibofimloc;化合物Antibiotic-202VRT-1353385|||Antibiotic-202|||Antibiotic 202;VRT-1353385|||Antibiotic-2
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
价 格:¥电议型 号:T4084产 地:中国大陆
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T40661ML-60218;化合物ML-60218ML-60218
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.
价 格:¥电议型 号:T40661产 地:中国大陆
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T40596Tasisulam sodium;Tasisulam sodiumLY 573636 sodium|||Tasisulam sodium;LY 573636 sodium|||Tasisulam so
Tasisulam is an anti-cancer compound that induces apoptosis through the intrinsic pathway, leading to the release of cytochrome c and caspase-dependent cell death. Additionally, tasisulam inhibits mitotic progression and triggers vascular normalization.
价 格:¥电议型 号:T40596产 地:中国大陆
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T40544NCGC00092410;化合物NCGC00092410ML008;ML008
NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM. It can be used for the study of Gaucher disease caused by mutation of glucocerebrase gene.
价 格:¥电议型 号:T40544产 地:中国大陆
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T4052KML29;化合物KML29KML29
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 μM). It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA).
价 格:¥电议型 号:T4052产 地:中国大陆
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T4030ML213;化合物ML213CID-3111211;CID-3111211
ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
价 格:¥电议型 号:T4030产 地:中国大陆