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T27083Crebinostat;化合物CrebinostatCrebinostat
Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respectively.Crebinostat increases the density of synapsin-1 punctae along dendrites in neurons in vitro. Crebinostat increased the density of synapsin-1 punctae along dendrites in neurons in vitro. crebinostat modulated chromatin-mediated neuroplasticity and enhanced memory in mice. crebinostat induced histone H3 and histone H4 acetylation and
价 格:¥电议型 号:T27083产 地:中国大陆
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T270768-Cyclopentyl-1,3-dimethylxanthineA1受体拮抗剂,CPTCPT|||A1受体拮抗剂,CPT
8-Cyclopentyl-1,3-dimethylxanthine (CPT)?is a potent antagonist of adenosine A1 receptor.
价 格:¥电议型 号:T27076产 地:中国大陆
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T26677ATC0175;化合物 T26677ATC 0175|||ATC-0175;ATC 0175|||ATC-0175
ATC0175 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.
价 格:¥电议型 号:T26677产 地:中国大陆
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T26676ATC0065;化合物 T26676ATC 0065|||ATC-0065;ATC 0065|||ATC-0065
ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.
价 格:¥电议型 号:T26676产 地:中国大陆
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T26252PI3Kδ-IN-3;PI3Kδ抑制剂3TC KHNS 11;TC KHNS 11
PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.
价 格:¥电议型 号:T26252产 地:中国大陆
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T26226SRTCX1002;化合物 T26226SRTCX 1002|||SRTCX-1002;SRTCX 1002|||SRTCX-1002
SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.
价 格:¥电议型 号:T26226产 地:中国大陆
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T26096RJR-2403 oxalate;化合物 T26096RJR 2403 oxalate|||Rivanicline oxalate|||TC-2403|||Metanicotine;RJR 2403
RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.
价 格:¥电议型 号:T26096产 地:中国大陆
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T25826MMV024101;化合物 T25826MMV-024101|||TCMDC 134293|||TCMDC134293|||TCMDC-134293|||MMV 024101;MMV-024101||
MMV024101 is a PI4K inhibitor. MMV024101 exhibits submicromolar potency against P. falciparum NF54 (IC50 =543 nM), low aqueous solubility (<5 μM), and rapid clearance by mouse liver microsomes with only 2% of parent compound remaining after 30 min of incubation.
价 格:¥电议型 号:T25826产 地:中国大陆
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T25808MI 1544;化合物 T25808Attcpl-LHRH|||AttcplLHRH|||MI-1544|||MI1544|||Attcpl LHRH;Attcpl-LHRH|||AttcplLHRH
MI 1544 is a LHRH antagonist.
价 格:¥电议型 号:T25808产 地:中国大陆
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T25687Leukotriene C4;白三烯C4LTC4|||Leukotriene C;白三烯C4|||LTC4|||Leukotriene C
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion in the lung and produces contractions of nonvascular and some vascular smooth muscle.
价 格:¥电议型 号:T25687产 地:中国大陆
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T25160BITC-SG;化合物 T25160BITC-SG
BITC-SG inhibits human glutathione S-transferase P1-1 by S-thiocarbamoylation.
价 格:¥电议型 号:T25160产 地:中国大陆
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T24860TC-G1003;化合物 T24860TC G1003;TC G1003
TC-G1003 is an effective agonist of the somatostatin sst2 receptor.
价 格:¥电议型 号:T24860产 地:中国大陆
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T24859TC-AQP1-1;化合物TC-AQP1-1TC-AQP1-1
TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.
价 格:¥电议型 号:T24859产 地:中国大陆
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T24857TBTC;化合物 T24857TBTC
TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer´s disease model mice.
价 格:¥电议型 号:T24857产 地:中国大陆
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T24682PTC725;化合物 T24682PTC-725|||PTC 725;PTC-725|||PTC 725
PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.
价 格:¥电议型 号:T24682产 地:中国大陆
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T24216JTC-017;化合物 T24216JTC 017;JTC 017
JTC-017 is an antagonist of Corticotropin-releasing hormone receptor 1.
价 格:¥电议型 号:T24216产 地:中国大陆
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T2400Candesartan Cilexetil;坎地沙坦酯TCV-116;TCV-116|||坎地沙坦酯|||坎地沙坦西酯
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.
价 格:¥电议型 号:T2400产 地:中国大陆
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T2373Vipadenant;化合物VipadenantCEB-4520|||BIIB-014;CEB-4520|||BIIB-014
Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM).
价 格:¥电议型 号:T2373产 地:中国大陆
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T23568LDV FITC;化合物 T23568LDV FITC
fluorescent ligand that binds to the α4β1 integrin (VLA-4)
价 格:¥电议型 号:T23568产 地:中国大陆
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T23450TCS PrP Inhibitor 13;化合物TCS PrP Inhibitor 135-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One;5-(4-Nitroph
TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
价 格:¥电议型 号:T23450产 地:中国大陆