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T23429KDM2/7-IN-1;化合物 T23429TC-E 5002;TC-E 5002
Selective histone demethylase KDM2/7 subfamily inhibitor
价 格:¥电议型 号:T23429产 地:中国大陆
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T23426TC-A 2317 hydrochloride;化合物TC-A 2317 hydrochlorideTC-A 2317 hydrochloride
TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A with a Ki of 1.2 nM compared to Aurora kinase B with a Ki of 101 nM. TC-A 2317 hydrochloride shows antitumor activity.
价 格:¥电议型 号:T23426产 地:中国大陆
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T23425TC 2559 difumarate;化合物 T23425TC 2559 difumarate
partial agonist of α4β2 nicotinic acetylcholine receptor
价 格:¥电议型 号:T23425产 地:中国大陆
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T23424TC 1698 dihydrochloride;化合物 T23424TC 1698 dihydrochloride
nicotinic α7 receptor agonist
价 格:¥电议型 号:T23424产 地:中国大陆
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T23252Rp-8-Br-PET-cGMPS化合物 T23252Rp 8 Br PET cGMPS|||Rp8BrPETcGMPS
cGMP-dependent protein kinase (PKG) inhibitor
价 格:¥电议型 号:T23252产 地:中国大陆
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T23007MM 77 dihydrochloride;MM 77二盐酸盐FITC-Dextran (60842-46-8 MW 4000);MM 77二盐酸盐
MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.
价 格:¥电议型 号:T23007产 地:中国大陆
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T22692CPCCOEt;化合物CPCCOEtCPCCOEt
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
价 格:¥电议型 号:T22692产 地:中国大陆
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T22591ATC 0175 hydrochloride;ATC 0175 盐酸盐ATC 0175 hydrochloride
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders.
价 格:¥电议型 号:T22591产 地:中国大陆
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T2253TCS PIM-1 1;化合物TCS PIM-1 1SC 204330;3-氰基-4-苯基-6-(3-溴-6-羟基苯基)-2(1H)-吡啶酮|||SC 204330
TCS PIM-1 1 (SC 204330)(sc-204330) is a effective and specific ATP-competitive Pim-1 kianse inhibitor (IC50: 50 nM) , exhibits good specific over MEK1/MEK2 and Pim-2(IC50s >20, 000 nM).
价 格:¥电议型 号:T2253产 地:中国大陆
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T225083-CPMT;化合物3-CPMTChlortropbenzyl hydrochloride|||3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabic
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
价 格:¥电议型 号:T22508产 地:中国大陆
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T2234TCS JNK 5a;化合物SC202671SC202671|||SC 202671|||N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-na
TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
价 格:¥电议型 号:T2234产 地:中国大陆
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T22159TCS HDAC6 20b;化合物 T22159TCS HDAC6 20b
TCS HDAC6 20b is a HDAC6 -selective inhibitor that blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells [1].
价 格:¥电议型 号:T22159产 地:中国大陆
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T22158TCS 3035;化合物 T22158TCS 3035
GPR35 agonist 4 (compound 10) serves as a potent GPR35 agonist, showcasing a pEC50 of 5.86, indicating its high potency towards both human and rat GPR35. Notably, the mutation of arginine at position 3.36 results in the loss of the compound´s agonist function on GPR35 [1].
价 格:¥电议型 号:T22158产 地:中国大陆
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T22157TCS 2002;化合物 T22157TCS 2002
GSK-3β inhibitor 9 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC 50 of 35 nM. GSK-3β inhibitor 9 exhibits good pharmacokinetic profiles including favorable BBB penetration. GSK-3β inhibitor 9 is able to be used for the research of Alzheimer’s disease [1].
价 格:¥电议型 号:T22157产 地:中国大陆
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T22043BCATc Inhibitor 2;化合物BCATc Inhibitor 2BCATc Inhibitor 2
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake, and demonstrated neuroprotective efficacy in vivo[1]. Branched-chain amino acid transferases (BCATs) have been implicated in catalyzing reversible transamination of isoleucine, leucine, and valine branched-chain amino acids to their corresponding α-keto acids, generating L-gluta
价 格:¥电议型 号:T22043产 地:中国大陆
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T21916TC-SP 14;化合物 T21916TC-SP 14
TC-SP 14, also known as compound 14, is a highly active and potent S1P1 agonist with oral bioavailability. It exhibits an EC50 value of 0.042 μM, indicating its strong binding affinity to the S1P1 receptor. Notably, its interaction with the S1P3 receptor is minimal, as evidenced by an EC50 value of 3.47 μM. TC-SP 14 demonstrates significant pharmacological effects, including a marked reduction in blood lymphocyte counts and the attenuation of delayed type hypersensitivity response to antigen cha
价 格:¥电议型 号:T21916产 地:中国大陆
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T21826TC-E 5003化合物TC-E 5003NSC 30176
TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.
价 格:¥电议型 号:T21826产 地:中国大陆