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T17015TCO-PEG4-acid；化合物 T17015TCO-PEG4-acid
TCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17015产 地：中国大陆
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T17014TCO-NHS ester化合物TCO-NHS esterTCO-NHS ester|||TCONHS ester|||TCO NHS ester
TCO-NHS ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17014产 地：中国大陆
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T17013TCO-C3-PEG3-C3-amine；化合物 T17013TCO-C3-PEG3-C3-amine
TCO-C3-PEG3-C3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17013产 地：中国大陆
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T17012TCO-amine；化合物 T17012TCO-amine
TCO-amine is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17012产 地：中国大陆
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T17011TCH-165；化合物TCH-165TCH-165
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.
价 格：￥电议型 号：T17011产 地：中国大陆
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T17010TC13172；化合物 T17010TC13172
TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2 nM for HT-29 cells).
价 格：￥电议型 号：T17010产 地：中国大陆
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T17009TC-S 7009；化合物TC-S 7009TC-S 7009
TC-S 7009 is a potent and selective HIF-2α inhibitor (Kd: 81 nM). The affinity of TC-S 7009 to HIF-2α was higher than that of HIF-1α (Kd >> 5μM). TC-S 7009 disrupts HIF-2α heterodimerization, reduces HIF-2α target gene expression, and reduces dna binding activity.
价 格：￥电议型 号：T17009产 地：中国大陆
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T17008TC-S 7005；化合物TC-S 7005TC-S 7005
TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).
价 格：￥电议型 号：T17008产 地：中国大陆
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T17007TC-Mps1-12化合物 T17007TCMps112|||TC-Mps-1-12|||TC Mps1 12
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
价 格：￥电议型 号：T17007产 地：中国大陆
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T17006TC-I 2014；化合物TC-I 2014TC-I 2014
TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively).
价 格：￥电议型 号：T17006产 地：中国大陆
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T17004TC-DAPK 6；化合物TC-DAPK 6TC-DAPK 6
TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.
价 格：￥电议型 号：T17004产 地：中国大陆
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T16830S-MTC；化合物 T16830S-MTC
S-MTC is a selective inhibitor of type I nitric oxide synthase.
价 格：￥电议型 号：T16830产 地：中国大陆
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T16727Relacorilant；化合物RelacorilantCORT 125134；CORT 125134
Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively). Relacorilant has the potential for Cushing’s syndrome treatment.
价 格：￥电议型 号：T16727产 地：中国大陆
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T16680PTC-028；化合物PTC-028PTC-028
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
价 格：￥电议型 号：T16680产 地：中国大陆
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T16489Darigabat；化合物 DarigabatCVL-865|||PF-6372865|||PF-06372865；CVL-865|||PF-6372865|||PF-06372865
Darigabat (PF-06372865) is an orally active and selective GABAA receptor modulator that crosses the blood-brain barrier and exhibits anxiolytic activity, with Ki values of 2.9 nM, 21 nM, and 134 nM for α2, α1 PAM, and α2 PAM, respectively.Darigabat is used in the study of anxiety disorders and epilepsy.
价 格：￥电议型 号：T16489产 地：中国大陆
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T16341Notch inhibitor 1；化合物 T16341Notch inhibitor 1
Notch inhibitor 1 is an effective Notch inhibitor (IC50s: 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively). Notch inhibitor 1 is also used in the research of cancer.
价 格：￥电议型 号：T16341产 地：中国大陆
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T15284FITC异硫氰酸荧光素酯Fluorescein 5-isothiocyanate|||异硫氰酸荧光素酯
FITC (Fluorescein 5-isothiocyanate) is a derivative of fluorescein for the labeling of amines.
价 格：￥电议型 号：T15284产 地：中国大陆
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T15250ETC-206；化合物ETC-206ETC-206
ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
价 格：￥电议型 号：T15250产 地：中国大陆
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T15025LCY5 triethylamine saltCY5三乙胺盐CY5 triethylamine salt(146368-11-8 Free base)
CY5 triethylamine salt is a water-soluble dye, Excitation (nm):649, Emission (nm): 670.
价 格：￥电议型 号：T15025L产 地：中国大陆
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T15024Silmitasertib sodium salt；化合物Silmitasertib sodium saltCX-4945 sodium salt；CX-4945 sodium salt
Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
价 格：￥电议型 号：T15024产 地：中国大陆
