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已选条件
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T18755TCO-PEG11-TCO;化合物 T18755TCO-PEG11-TCO
TCO-PEG11-TCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18755产 地:中国大陆
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T18754TCO-PEG1-Val-Cit-PABC-OH;化合物 T18754TCO-PEG1-Val-Cit-PABC-OH
TCO-PEG1-Val-Cit-PABC-OH, a cleavable 1-unit PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18754产 地:中国大陆
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T18753TCO-PEG1-Val-Cit-OH;化合物 T18753TCO-PEG1-Val-Cit-OH
TCO-PEG1-Val-Cit-OH is a cleavable 1-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18753产 地:中国大陆
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T18752TCO-PEG-TCO (MW 5000);化合物 T18752TCO-PEG-TCO (MW 5000)
TCO-PEG-TCO (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18752产 地:中国大陆
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T18751TCO-OH;化合物 T18751TCO-OH
TCO-OH is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18751产 地:中国大陆
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T18676(S)-TCO-PEG3-amine;化合物 T18676(S)-TCO-PEG3-amine
(S)-TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18676产 地:中国大陆
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T18652RTC-30;化合物 T18652RTC-30
RTC-30 is an optimized phenothiazine compound possessing potent anti-cancer properties. It is formulated with a hydroxylated linker (N) which enhances its oral bioavailability[1].
价 格:¥电议型 号:T18652产 地:中国大陆
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T18648(R)-TCO-OH;化合物 T18648(R)-TCO-OH
(R)-TCO-OH is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18648产 地:中国大陆
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T18440N-(Mal-PEG6)-N-bis(PEG7-TCO);化合物 T18440N-(Mal-PEG6)-N-bis(PEG7-TCO)
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a polyethylene glycol (PEG)-based PROTAC linker employed for PROTAC synthesis[1].
价 格:¥电议型 号:T18440产 地:中国大陆
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T1805Ataluren;化合物AtalurenPTC124;PTC124
Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.
价 格:¥电议型 号:T1805产 地:中国大陆
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T17986Gly-Gly-Gly-PEG3-TCO;化合物 T17986Gly-Gly-Gly-PEG3-TCO
Gly-Gly-Gly-PEG3-TCO is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17986产 地:中国大陆
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T17799DBCO-PEG4-SS-TCO;化合物 T17799DBCO-PEG4-SS-TCO
DBCO-PEG4-SS-TCO is a cleavable 4-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs)[1]. It plays a crucial role in connecting the drug payload to the antibody, enabling targeted drug delivery.
价 格:¥电议型 号:T17799产 地:中国大陆
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T17792DBCO-PEG3-TCO;化合物 T17792DBCO-PEG3-TCO
DBCO-PEG3-TCO is a non-cleavable three-unit polyethylene glycol (PEG) linker employed for synthesizing antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17792产 地:中国大陆
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T17401Amino-bis-PEG3-TCO;化合物 T17401Amino-bis-PEG3-TCO
Amino-bis-PEG3-TCO is a three-unit cleavable polyethylene glycol (PEG) linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17401产 地:中国大陆
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T17020TCS 2314;化合物 T17020TCS-2314|||TCS 2314|||TCS 2314|||TCS2314;TCS-2314|||TCS 2314|||TCS 2314|||TCS2314
TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).
价 格:¥电议型 号:T17020产 地:中国大陆
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T17019TCS 21311;化合物TCS 21311NIBR3049;NIBR3049
TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK2, and TYK2.
价 格:¥电议型 号:T17019产 地:中国大陆
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T17018TCPOBOP;化合物TCPOBOPTCPOBOP
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
价 格:¥电议型 号:T17018产 地:中国大陆
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T17017TCO-PEG4-NHS ester;化合物TCO-PEG4-NHS esterTCO-PEG4-NHS ester
TCO-PEG4-NHS ester is a PROTAC linker bridge belonging to the PEG class.TCO-PEG4-NHS ester can be used to synthesize a wide range of PROTAC molecules.TCO-PEG4-NHS ester is a cleavable and synthetic ADC that can be used in the synthesis of antibody activated molecule conjugates (ADCs). bridge.
价 格:¥电议型 号:T17017产 地:中国大陆
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T17016TCO-PEG4-biotin;化合物TCO-PEG4-biotinTCO-PEG4-biotin
TCO-PEG4-biotin is a PROTAC linker belonging to the PEG class.TCO-PEG4-biotin can be used to synthesise a range of PROTAC molecules.
价 格:¥电议型 号:T17016产 地:中国大陆
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T17015L(S)-TCO-PEG4-acid;化合物 T17015L(S)-TCO-PEG4-acid
(S)-TCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17015L产 地:中国大陆