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产品数:86101
参观次数:3254719
已选条件
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T8234ML401ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401
ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
价 格:¥电议型 号:T8234产 地:中国大陆
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T8449TC-I2000TCI2000,TC-I-2000,TC I2000
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.
价 格:¥电议型 号:T8449产 地:中国大陆
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T6479Dovitinib lactate hydrateVEGFR1,FGFR1,TKI258 lactate,SCFR,CD117,Dovitinib lactate hydrate,FGFR,Fms l
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
价 格:¥电议型 号:T6479产 地:中国大陆
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T9836(E)-SI-2(E)SI2,(E) SI 2
(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
价 格:¥电议型 号:T9836产 地:中国大陆
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T6153IcotinibIcotinib,Inhibitor,BPI2009,BPI 2009,ErbB-1,HER1,inhibit,EGFR,Epidermal growth factor recepto
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.
价 格:¥电议型 号:T6153产 地:中国大陆
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T6764LATI-2341 acetate(1337878-62-2 free base)ATI2341 acetate(1337878622 free base),ATI 2341 acetate(13378
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization.
价 格:¥电议型 号:T6764L产 地:中国大陆
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T7522GI254023XSRI 028594,SRI028594,GI 4023,inhibit,GI-254023X,Matrix metalloproteinases,SRI-028594,Inhibi
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation.
价 格:¥电议型 号:T7522产 地:中国大陆
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T8443MCI-225MCI225,MCI 225
MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.
价 格:¥电议型 号:T8443产 地:中国大陆
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T93351,1’-Methylenedi-2-naphthol1,1’Methylenedi2naphthol,1,1’ Methylenedi 2 naphthol
1,1´-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).
价 格:¥电议型 号:T9335产 地:中国大陆
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T8493IngliforibInhibitor,GPi296,GPi-296,CP368296,CP-368296,Ingliforib,inhibit
Ingliforib is a novel glycogen phosphorylase inhibitor,has antihyperglycemic and cardioprotective properties.
价 格:¥电议型 号:T8493产 地:中国大陆
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T6736ZafirlukastLeukotriene Receptor,Zafirlukast,ICI-204219,Inhibitor,inhibit,ICI204219
Zafirlukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
价 格:¥电议型 号:T6736产 地:中国大陆
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T8801SRI-29329Cyclin dependent kinase,inhibit,SRI29329,SRI-29329,Inhibitor,SRI 29329,CDK
SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).
价 格:¥电议型 号:T8801产 地:中国大陆
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T7323BCI-215specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
价 格:¥电议型 号:T7323产 地:中国大陆
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T7156NIBR189Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U93
NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
价 格:¥电议型 号:T7156产 地:中国大陆
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T25952Phox-I2Phox-I-2
Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
价 格:¥电议型 号:T25952产 地:中国大陆
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T3469PCI-27483Inhibitor,inhibit,PCI 27483,PCI-27483
PCI 27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg, respectively.
价 格:¥电议型 号:T3469产 地:中国大陆
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T6289DovitinibCHIR-258;TKI258;多韦替尼;度维替尼
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER
价 格:¥电议型 号:T6289产 地:中国大陆
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T6026CPI-203CPI 203;CPI203
CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
价 格:¥电议型 号:T6026产 地:中国大陆
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T4337PCI 29732PCI29732;PCI-29732
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
价 格:¥电议型 号:T4337产 地:中国大陆
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T4325COTI-2COTI 2;COTI2
COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.
价 格:¥电议型 号:T4325产 地:中国大陆