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产品数:86101
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已选条件
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TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-κB,cognitive,inhibit,BDNF,synapse,Pratensei
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
价 格:¥电议型 号:TN2100产 地:中国大陆
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TN1637EurycomalactoneDNA double-strand,Eurycomalactone,NF-κB,protein synthesis,Inhibitor,Nuclear factor-ka
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα.
价 格:¥电议型 号:TN1637产 地:中国大陆
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TN13418-Deoxygartanin8Deoxygartanin,Parasite,8-Deoxygartanin,inhibit,Nuclear factor-kappaB,Inhibitor,Nucle
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer´s disease (AD) and could be promising compounds for the therapy of AD.
价 格:¥电议型 号:TN1341产 地:中国大陆
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T7330Nucleozininhibit,Nucleozin,viral,Inhibitor,infection,Influenza Virus,nuclear,nucleoprotein,virus,rep
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
价 格:¥电议型 号:T7330产 地:中国大陆
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T9115Vanillic AcidNuclear factor-κB,Vanillic Acid,NF-κB,inhibit,Bacterial,Nuclear factor-kappaB,Endogenou
Vanillic acid is used as a condiment in food,which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic acid.
价 格:¥电议型 号:T9115产 地:中国大陆
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T8799(E/Z)-IT-603GVHD,Inhibitor,Nuclear factor-kappaB,(E/Z)IT603,immunomodulatory,(E/Z) IT 603,disease,in
IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity.
价 格:¥电议型 号:T8799产 地:中国大陆
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T8550NDMC101rheumatoid arthritis,inhibit,RAW 264.7,NSAID,Bone,Inhibitor,Nuclear factor-κB,NF-κB,DPP,NDMC1
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
价 格:¥电议型 号:T8550产 地:中国大陆
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T79792-Hydroxychalconeinhibit,Inhibitor,Apoptosis,Nuclear factor-κB,Nuclear factor-kappaB,NF-κB,TNBC,2 Hy
2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.
价 格:¥电议型 号:T7979产 地:中国大陆
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T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi
价 格:¥电议型 号:T6S1572产 地:中国大陆
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TN1410Asperulosidic acidERK,Inhibitor,Nuclear factor-κB,Extracellular signal regulated kinases,NF-κB,Nucle
Asperulosidic acid has anti-tumor, anti-oxidant, and anti-inflammatory activities.ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways.
价 格:¥电议型 号:TN1410产 地:中国大陆
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TL0016SulforapheneInhibitor,Sulforaphene,ERK,NF-κB,Nuclear factor-κB,Nuclear factor-kappaB,Extracellular s
Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
价 格:¥电议型 号:TL0016产 地:中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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T6S0840EngeletinNuclear factor-kappaB,Engeletin,inhibit,NF-κB,Inhibitor,Nuclear factor-κB
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
价 格:¥电议型 号:T6S0840产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T6S1371Isovitexininhibit,Isovitexin,Nuclear factor-kappaB,Inhibitor,Nuclear factor-κB,NF-κB,JNK
1. Isovitexin exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.
价 格:¥电议型 号:T6S1371产 地:中国大陆
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T6S0781PhellodendrineNuclear factor-kappaB,inhibit,Akt,Nuclear factor-κB,Inhibitor,PKB,Protein kinase B,NF-
1. Phellodendrine has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
价 格:¥电议型 号:T6S0781产 地:中国大陆
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T9010IMM-H007JNK,Nuclear factor-κB,WS 070117,IMM H007,AP-1,inflammatory,WS070117,inhibit,AMPK,atheroscler
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
价 格:¥电议型 号:T9010产 地:中国大陆
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T6429Caffeic Acid Phenethyl EsterApoptosis,Caffeic Acid Phenethyl Ester,Nuclear factor-kappaB,Inhibitor,N
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypo
价 格:¥电议型 号:T6429产 地:中国大陆
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T7904SR 19881SR-19881,estrogen-related receptor,nuclear receptor,amide,SR19881,phenol,ligand binding doma
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).
价 格:¥电议型 号:T7904产 地:中国大陆
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TN1712GossypinAntiinflammatory,inhibit,Nuclear factor-κB,Gossypin,Inhibitor,Antioxidant,Anticancer,cardiov
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation, carcinogenesis, and angiogenesis.
价 格:¥电议型 号:TN1712产 地:中国大陆