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TN1721Gypenoside LMAPK,Extracellular signal regulated kinases,NF-κB,Nuclear factor-κB,saponin,anti-tumor,N
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory activity.
价 格：￥电议型 号：TN1721产 地：中国大陆
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T9917DenosumabDenosumab,Immunoglobulin G2,Nuclear factor-kappaB,NF-κB,Immunoglobulin G-2,RANKL,Inhibitor,
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
价 格：￥电议型 号：T9917产 地：中国大陆
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TN2008OkaninToll-like Receptor (TLR),Nuclear factor-κB,NF-κB,Inhibitor,Nuclear factor-kappaB,Okanin,inhibi
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.
价 格：￥电议型 号：TN2008产 地：中国大陆
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TN1141Isodeoxyelephantopininhibit,Reactive Oxygen Species,Inhibitor,Isodeoxyelephantopin,NF-κB,Nuclear fac
Isodeoxyelephantopin can inhibit the growth of various tumor cells.
价 格：￥电议型 号：TN1141产 地：中国大陆
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TN1525Convallatoxinpsoriasis,Nuclear factor-κB,P-gp,Inhibitor,anti-proliferative,colitic,anti-inflammatory
Convallatoxin is a natural product.
价 格：￥电议型 号：TN1525产 地：中国大陆
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TN2244Sulfuretininflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregati
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
价 格：￥电议型 号：TN2244产 地：中国大陆
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T8858DTHIBdegradation,HSP27,Inhibitor,inhibit,HSP70,HSF1,HSP,DTHIB,HSP90,cancer,nuclear,anticancer,Heat s
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
价 格：￥电议型 号：T8858产 地：中国大陆
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T6S1487Ginsenoside Rg5Nuclear factor-κB,Inhibitor,Ginsenoside Rg5,Cyclooxygenase,Ginsenoside Rg 5,NF-κB,COX
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer´s disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. 4. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasc
价 格：￥电议型 号：T6S1487产 地：中国大陆
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T6S1966CurculigosideCurculigoside,Janus kinase,NF-κB,JAK,Nuclear factor-κB,Nuclear factor-kappaB,STAT,inhib
1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidati
价 格：￥电议型 号：T6S1966产 地：中国大陆
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TQ0198Phorbol 12-myristate 13-acetatePKC,SphK,Nuclear factor-κB,Protein kinase C,Inhibitor,Phorbol 12 myri
Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and PKC activator.
价 格：￥电议型 号：TQ0198产 地：中国大陆
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TQ018514-Deoxy-11,12-didehydroandrographolideinhibit,Nuclear factor-κB,Inhibitor,14 Deoxy 11,12 didehydroa
14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.
价 格：￥电议型 号：TQ0185产 地：中国大陆
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T28362PF-02413873nonsteroidal,inhibit,PF 2413873,Progesterone Receptor,endometrial,PF-2413873,nuclear,PF 0
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.
价 格：￥电议型 号：T28362产 地：中国大陆
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T6495EUK-134Inhibitor,Free,mitoprotective,Nephrotoxicity,antioxidant,SODm,species,Nuclear factor-kappaB,N
EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
价 格：￥电议型 号：T6495产 地：中国大陆
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T8879MR837PWWP1,nuclear,MR837,SET,NSD2,Histone Methyltransferase,MR 837,domain,inhibit,Inhibitor,MR-837
ZINC30303842 is a NSD2-PWWP1 antagonist.
价 格：￥电议型 号：T8879产 地：中国大陆
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T6454CORM-3inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Recepto
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
价 格：￥电议型 号：T6454产 地：中国大陆
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TN118211-?Keto-?beta-?boswellic acidLOX,Inhibitor,11 ?Keto ?beta ?boswellic acid,Nuclear factor-κB,Nuclear
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase
价 格：￥电议型 号：TN1182产 地：中国大陆
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T19041Hoechst S 769121Hoechst S 769121,Nuclear yellow,
Hoechst S 769121 (Nuclear yellow) is a fluorescence dye that can bound to DNA (excitation/emission maxima ~335/495 nm).
价 格：￥电议型 号：T19041产 地：美洲
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T19042NucPE1NucPE1,Nuclear Peroxy Emerald 1,
NucPE1, a nuclear-localized fluorescent hydrogen peroxide, is specifically localized to cellular nuclei without appended targeting moieties.
价 格：￥电议型 号：T19042产 地：美洲
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T838944A7C-301-Nurr1 Agonist；化合物 4A7C-301-Nurr1 Agonist4A7C-301-Nuclear Receptor-Related 1；4A7C-301-Nuclea
The compound 4A7C-301-Nurr1 agonist is a specific agonist for the nuclear receptor-related 1 (Nurr1). By binding to the Nurr1 ligand-binding domain with an IC50 value of 48.22 nM, it enhances the transcriptional activity of both Nurr1-LBD and the full-length Nurr1, as demonstrated in reporter assays using SK-N-BE(2)C human neuroblastoma cells, with EC50 values of 6.53 and 50-70 ?M, respectively. Additionally, administration of 4A7C-301-Nurr1 agonist at a dosage of 5 mg/kg per day has been shown
价 格：￥电议型 号：T83894产 地：中国大陆
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T83727Tat-NTS Peptide TFA；化合物 Tat-NTS Peptide TFATat-Nuclear Translocation Signal Peptide；Tat-Nuclear Tran
Tat-NTS peptide, a cell-penetrating compound, comprises the HIV-1 Tat protein transduction domain fused with a 10-amino acid sequence (residues 228-237) from the repeat III domain of annexin A1, serving as a nuclear translocation signal (NTS). This peptide hinders the interaction between annexin A1 and importin β, obstructing annexin A1´s nuclear entry in primary mouse hippocampal neurons. Tat-NTS effectively prevents apoptosis triggered by glucose-oxygen deprivation and reperfusion in the
价 格：￥电议型 号：T83727产 地：中国大陆
