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T14372AZD1979;化合物 T14372AZD1979
AZD1979 is an antagonist of Melanin-concentrating hormone receptor 1 (MCHr1) (IC50: 12 nM).
价 格:¥电议型 号:T14372产 地:中国大陆
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T14279Aminooxy-PEG8-methane;化合物 T14279Aminooxy-PEG8-methane
Aminooxy-PEG8-methane is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14279产 地:中国大陆
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T14217AMG 579;化合物AMG 579AMG-579;AMG-579
AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).
价 格:¥电议型 号:T14217产 地:中国大陆
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T14205AM679;化合物 T14205AM679
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition profile (IC50 3A4 = 16.7 lM, 2C9 = 3.7 lM, 2D6 >30 lM), no time dependent inhibition against CYP3A4 (0.003 min-1 vs 0.057 min-1 for troleandomycin control 10 uM) and no CYP3A4 induction. AM679 has an excellent hWB IC50 potency of 154 nM. Target: FLAP in vitro: AM679 showed excell
价 格:¥电议型 号:T14205产 地:中国大陆
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T1418Bucladesine sodium;布拉地新钠盐dbcAMP|||Dibutyryl-cAMP sodium salt|||Dibutyryl-cAMP|||DC2797|||Sodium dibu
Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-inflammatory activity.
价 格:¥电议型 号:T1418产 地:中国大陆
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T14179Aliconazole;阿利康唑Aliconazole
Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.
价 格:¥电议型 号:T14179产 地:中国大陆
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T14079A81988;化合物 T14079Abbott81988;Abbott81988
A81988 is an antagonist of angiotensin AT1 receptors.
价 格:¥电议型 号:T14079产 地:中国大陆
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T140555Z-7-Oxozeaenol;化合物5Z-7-OxozeaenolFR148083|||L783279|||LL-Z 1640-2;FR148083|||L783279|||LL-Z 1640-2
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
价 格:¥电议型 号:T14055产 地:中国大陆
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T13979(S)-3-Hydroxybutanoic acid;(S)-3-羟基丁酸L-β-Hydroxybutyric acid|||(S)-β-Hydroxybutanoic acid|||L-(+)-3-
(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.
价 格:¥电议型 号:T13979产 地:中国大陆
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T13879(S)-Verapamil hydrochloride;化合物 T13879(S)-(-)-Verapamil hydrochloride;(S)-(-)-Verapamil hydrochlorid
(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.
价 格:¥电议型 号:T13879产 地:中国大陆
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T13799NQO1 substrateNQO1底物NQO-1 substrate|||NQO1 substrate
NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
价 格:¥电议型 号:T13799产 地:中国大陆
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T13798Nortanshinone;化合物 T13798Nortanshinone
Nortanshinone is a natural product isolated from Dan-Shen.
价 格:¥电议型 号:T13798产 地:中国大陆
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T13795Nicotinamide riboside;烟酰胺核糖Nicotinamide riboside
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
价 格:¥电议型 号:T13795产 地:中国大陆
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T13794Neridronate;奈立膦酸Neridronate
Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB).
价 格:¥电议型 号:T13794产 地:中国大陆
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T13793Neohesperidose;新橙皮糖Neohesperidose
Neohesperidose is a natural product isolated from species of typha.
价 格:¥电议型 号:T13793产 地:中国大陆
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T13792Nampt-IN-3;化合物 T13792Nampt-IN-3
Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).
价 格:¥电议型 号:T13792产 地:中国大陆
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T13791N2-methylguanine化合物 N2-methylguanine6-羟基-2-氨甲基嘌呤
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.
价 格:¥电议型 号:T13791产 地:中国大陆
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T13790N-Methyl Duloxetine hydrochloride;化合物 T13790N-Methyl Duloxetine hydrochloride
N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.
价 格:¥电议型 号:T13790产 地:中国大陆
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T1379L-5-Hydroxytryptophan;5-羟基色氨酸L-oxitriptan|||Oxitriptan|||L-5-HTP;5-羟基色氨酸|||L-oxitriptan|||Oxitriptan
L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
价 格:¥电议型 号:T1379产 地:中国大陆
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T13779MPT0B392;化合物 T13779MPT0B392
MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.
价 格:¥电议型 号:T13779产 地:中国大陆