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T11606ICA-105665;化合物 T11606PF-04895162;PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格:¥电议型 号:T11606产 地:中国大陆
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T1158Phenoxybenzamine hydrochloride;盐酸酚苄明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl;苯氧苯札明|||NCI-c01661
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
价 格:¥电议型 号:T1158产 地:中国大陆
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T11566HIV-1 integrase inhibitor;化合物 T11566HIV-1 integrase inhibitor
Hiv-1 integrase inhibitor is an effective anti-HIV drug.
价 格:¥电议型 号:T11566产 地:中国大陆
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T11534LHaemanthamine hydrochloride (466-75-1 free base);化合物 T11534LHaemanthamine hydrochloride;Haemanthamin
Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsant activities.
价 格:¥电议型 号:T11534L产 地:中国大陆
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T11522GYKI 52466 dihydrochloride;化合物 T11522GYKI 52466 dihydrochloride
GYKI 52466 dihydrochloride is orally active and non-competitive kainate- and AMPA-activated currents antagonist (IC50s: 7.5 μM and 11 μM). It is inactive against NMDA or γ-aminobutyric acid responses. It is a muscle relaxant and anticonvulsant agent and has good blood-brain barrier permeability.
价 格:¥电议型 号:T11522产 地:中国大陆
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T11521GW 766994;化合物 T11521GW 994;GW 994
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.
价 格:¥电议型 号:T11521产 地:中国大陆
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T11497Ganfeborole HCl;Ganfeborole 盐酸盐GSK3036656 HCl|||GSK656 HCl;GSK3036656 HCl|||GSK656 HCl
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM).
价 格:¥电议型 号:T11497产 地:中国大陆
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T11483GSK256066 Trifluoroacetate化合物 T11483GSK 256066 Trifluoroacetate|||GSK256066 (2,2,2-trifluoroacetic a
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T11483产 地:中国大陆
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T11470GSK 366;化合物 T11470GSK 366
GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).
价 格:¥电议型 号:T11470产 地:中国大陆
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T11466GSK-2793660;化合物 T11466GSK-2793660
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 is a bioactive dipeptide that can be used for the research of bronchiectasis [1] [2].
价 格:¥电议型 号:T11466产 地:中国大陆
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T11383GDP366;化合物GDP366GDP366
GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.
价 格:¥电议型 号:T11383产 地:中国大陆
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T11366Garcinol;山竹子素Garcinol
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.
价 格:¥电议型 号:T11366产 地:中国大陆
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T11266LFAS-IN-1 Tosylate;化合物 T11266LFAS-IN-1 Tosylate
FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.
价 格:¥电议型 号:T11266L产 地:中国大陆
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T11266FASN-IN-4;化合物 T11266FAS-IN-1;FAS-IN-1
FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.
价 格:¥电议型 号:T11266产 地:中国大陆
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T11246Etoricoxib-d4;依托考昔 D4MK-0663 D4|||L-791456 D4|||Etoricoxib D4;MK-0663 D4|||依托考昔 D4|||L-791456 D4|||E
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
价 格:¥电议型 号:T11246产 地:中国大陆
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T11166EHMT2-IN-1;化合物 T11166EHMT2-IN-1
EHMT2-IN-1 is a potent EHMT inhibitor, . Used in the research of blood disorder or cancer.with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2.
价 格:¥电议型 号:T11166产 地:中国大陆
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T1107Sarafloxacin hydrochloride;盐酸沙拉沙星Sarafloxacin HCl|||A-56620 (hydrochloride)|||A-56620 HCl;Sarafloxac
Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.
价 格:¥电议型 号:T1107产 地:中国大陆
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T10988LDegarelix acetate(214766-78-6 free base);化合物Degarelix acetateDegarelix acetate(214766-78-6 free base
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
价 格:¥电议型 号:T10988L产 地:中国大陆
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T10967DC_C66;化合物 T10967DC_C66
DC_C66 DC_C66 has good selectivity for CARM1, PRMT1 (IC50 = 21μM), PRMT6 (IC50 = 47μM) and PRMT5. It is a cell-permeable, selective co-activator related arginine methyltransferase 1 (CARM1) inhibitor with IC50 of 1.8 μM.
价 格:¥电议型 号:T10967产 地:中国大陆
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T10966DC-5163;化合物 T10966DC-5163
DC-5163 is a potent inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with IC50 of 176.3 nM and Kd of 3.192 μM. DC-5163 selectively inhibits cancer cell proliferation and induces apoptosis, and partially inhibits the glycolysis pathway.
价 格:¥电议型 号:T10966产 地:中国大陆