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T12866SCH 42495 racemate;化合物 T12866SCH 42495 (racemate);SCH 42495 (racemate)
SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral inhibitor of metalloendopeptidase (NEP), with antihypertensive effect.
价 格:¥电议型 号:T12866产 地:中国大陆
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T12860SC57666;化合物SC57666SC 57666|||SC57666|||SC-57666|||SC57666|||SC-57666;0
SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.
价 格:¥电议型 号:T12860产 地:中国大陆
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T12833Sardomozide;化合物 T12833CGP 48664|||SAM-486A;CGP 48664|||SAM-486A
Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC)(IC50 of 5 nM).
价 格:¥电议型 号:T12833产 地:中国大陆
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T12793(S)-BI 665915;化合物 T12793(S)-BI 665915
(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..
价 格:¥电议型 号:T12793产 地:中国大陆
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T12766RPR121056;化合物 T12766APC;APC
RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.
价 格:¥电议型 号:T12766产 地:中国大陆
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T12679(Rac)-VU 6008667;化合物(Rac)-VU 6008667(Rac)-VU 6008667
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has high CNS penetration.
价 格:¥电议型 号:T12679产 地:中国大陆
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T12669(Rac)-LM11A-31 dihydrochloride;化合物 T12669(Rac)-LM11A-31 dihydrochloride
(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride is a potent antagonist of proNGF (nerve growth factor).
价 格:¥电议型 号:T12669产 地:中国大陆
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T12668(Rac)-IDO1-IN-5;化合物 T12668(Rac)-IDO1-IN-5
(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5, a potent, selective, and brain-penetrating inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity. It specifically binds to apo-IDO1, which lacks heme, instead of mature heme-bound IDO1.
价 格:¥电议型 号:T12668产 地:中国大陆
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T12667(Rac)-Hesperetin;化合物 T12667(Rac)-Hesperetin
(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits potent inhibitory effects against human UGT activity, making it a broad-spectrum inhibitor. Furthermore, Hesperetin induces apoptosis through the activation of p38 MAPK.
价 格:¥电议型 号:T12667产 地:中国大陆
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T12665(Rac)-E1R;化合物 T12665(Rac)-E1R
(Rac)-E1R is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric (Sig1R PAM) modulator of for the treatment of cognition/memory disorders.
价 格:¥电议型 号:T12665产 地:中国大陆
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T12664(Rac)-BRD0705;化合物(Rac)-BRD0705(Rac)-BRD0705
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor of GSK3α.
价 格:¥电议型 号:T12664产 地:中国大陆
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T12663(Rac)-BMS-816336;化合物 T12663(Rac)-BMS-816336
(Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1].
价 格:¥电议型 号:T12663产 地:中国大陆
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T12662(Rac)-BL-918;化合物 T12662(Rac)-BL-918
(Rac)-BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson’s disease treatment [1].
价 格:¥电议型 号:T12662产 地:中国大陆
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T12661(Rac)-BI 703704;化合物 T12661(Rac)-BI 703704
(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).
价 格:¥电议型 号:T12661产 地:中国大陆
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T12660LBAY1238097;化合物BAY1238097BAY1238097
BAY1238097 is a potent and selective bromodomain and extra-terminal motif (BET) inhibitor with anticancer activity that exhibits strong antiproliferative activity in AML (Acute Myeloid Leukemia) and MM (Multiple Myeloma) models.BAY1238097 can be used for the study of advanced refractory malignancies.
价 格:¥电议型 号:T12660L产 地:中国大陆
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T12660(Rac)-BAY1238097;化合物 T12660(Rac)-BAY1238097
(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.
价 格:¥电议型 号:T12660产 地:中国大陆
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T1266Terfenadine;特非那定(±)-Terfenadine|||MDL-991;(±)-Terfenadine|||特非那定|||MDL-991
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.
价 格:¥电议型 号:T1266产 地:中国大陆
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T12647(R)-VU 6008667;化合物 T12647(R)-VU 6008667
(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).
价 格:¥电议型 号:T12647产 地:中国大陆