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T14966Cimetropium Bromide;西托溴铵DA-3177;西托溴铵|||DA-3177
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
价 格:¥电议型 号:T14966产 地:中国大陆
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T14911CD2665;化合物CD2665CD2665
CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.
价 格:¥电议型 号:T14911产 地:中国大陆
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T14908CCT367766;化合物CCT367766CCT367766
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low conc
价 格:¥电议型 号:T14908产 地:中国大陆
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T14878CAY10566;化合物CAY10566CAY10566
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..
价 格:¥电议型 号:T14878产 地:中国大陆
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T14866Carboxy-PEG2-sulfonic acid;化合物 T14866Carboxy-PEG2-sulfonic acid
Carboxy-PEG2-sulfonic acid is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14866产 地:中国大陆
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T1478Ondansetron hydrochloride dihydrate;盐酸昂丹司琼SN 307|||NSC 665799|||GR 38032|||Ondansetron hydrochloride
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
价 格:¥电议型 号:T1478产 地:中国大陆
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T14766BPH-715;化合物BPH-715BPH-715
BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.
价 格:¥电议型 号:T14766产 地:中国大陆
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T14670BMS-1166 hydrochloride;化合物 T14670BMS-1166 hydrochloride
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
价 格:¥电议型 号:T14670产 地:中国大陆
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T1466LDifloxacin HCl;化合物 T1466LDifloxacin HCl
Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic.
价 格:¥电议型 号:T1466L产 地:中国大陆
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T14669BMS-066;化合物 T14669BMS-066
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
价 格:¥电议型 号:T14669产 地:中国大陆
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T14668BMPS;化合物 T14668BMPS
BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T14668产 地:中国大陆
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T14667BLT-1;化合物BLT-1BLT-1
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.
价 格:¥电议型 号:T14667产 地:中国大陆
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T14666BL-1249;化合物BL-1249BL-1249
BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).
价 格:¥电议型 号:T14666产 地:中国大陆
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T14665LMotixafortide TFA(664334-36-5,Free);化合物Motixafortide TFATF 14016 TFA|||BKT140 TFA|||BL-8040 TFA|||T1
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ~1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
价 格:¥电议型 号:T14665L产 地:中国大陆
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T14665Motixafortide化合物 T14665BL-8040|||BKT140 (4-fluorobenzoyl)|||TF14016
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).
价 格:¥电议型 号:T14665产 地:中国大陆
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T14664BI 689648;化合物 T14664BI 689648
BI 689648 is a highly selective inhibitor of aldosterone synthase(CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively).
价 格:¥电议型 号:T14664产 地:中国大陆
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T14663Bis-Tos-(2-hydroxyethyl disulfide);化合物 T14663Bis-Tos-(2-hydroxyethyl disulfide)
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14663产 地:中国大陆
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T14662Bis-propargyl-PEG9;化合物 T14662Bis-propargyl-PEG9
Bis-propargyl-PEG9 is a PEG-based PROTAC linker employed in the synthesis of PROTACs. It is specifically utilized to synthesize the bivalent ligands of estrogen receptor[1].
价 格:¥电议型 号:T14662产 地:中国大陆
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T14661Bis-propargyl-PEG8;化合物 T14661Bis-propargyl-PEG8
Bis-propargyl-PEG8 (compound 16e) is a polyethylene glycol (PEG)-based linker that is employed in the synthesis of proteolysis targeting chimeras (PROTACs).
价 格:¥电议型 号:T14661产 地:中国大陆
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T14660Bis-propargyl-PEG7;化合物 T14660Bis-propargyl-PEG7
Bis-propargyl-PEG7 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). It is particularly employed for the synthesis of polymer-linked multimers of guanosine-3´,5´-cyclic monophosphates[1].
价 格:¥电议型 号:T14660产 地:中国大陆