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T16357DA-3003-1化合物 DA-3003-1NSC 663284
DA-3003-1 (DA-3003-1) is a membrane-permeable, potent and selective Cdc25 dual specificity phosphatase inhibitor with antitumor activity that inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C.
价 格：￥电议型 号：T16357产 地：中国大陆
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T16266NAMI-A；化合物NAMI-ANAMI-A
NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.
价 格：￥电议型 号：T16266产 地：中国大陆
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T16166N-[(4-Aminophenyl)methyl]adenosine；N-[(4-氨基苯基)甲基]腺苷N-[(4-Aminophenyl)methyl]adenosine
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
价 格：￥电议型 号：T16166产 地：中国大陆
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T16142MRT199665；化合物 T16142MRT199665
MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively). MRT199665 suppresses the phosphorylation of SIK substrate CRTC3 at S370. MRT199665 induces apoptosis in MEF2C-activated human acute myeloid leukemia (AML) cells.
价 格：￥电议型 号：T16142产 地：中国大陆
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T16126Monepantel；化合物 MonepantelAAD1566|||PPL-1；AAD1566|||PPL-1
Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.
价 格：￥电议型 号：T16126产 地：中国大陆
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T16066Metipranolol hydrochloride；化合物 T16066Metipranolol hydrochloride
Metipranolol hydrochloride is a non-selective blocking agent of the β adrenergic receptor.
价 格：￥电议型 号：T16066产 地：中国大陆
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T15966Mal-amido-PEG9-NH-Boc；化合物 T15966Mal-amido-PEG9-NH-Boc
Mal-amido-PEG9-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15966产 地：中国大陆
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T1591Ancitabine hydrochloride盐酸环胞苷NSC 145668 HCl|||盐酸环胞苷|||Cyclocytidine hydrochloride|||Cyclo-CMP hydroc
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycl
价 格：￥电议型 号：T1591产 地：中国大陆
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T15866m-PEG3-Tos；化合物 T15866m-PEG3-Tos
m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin[1].
价 格：￥电议型 号：T15866产 地：中国大陆
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T15815LY3295668；化合物AK-01AK-01；AK-01
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.
价 格：￥电议型 号：T15815产 地：中国大陆
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T15771Lobaplatin；络铂D-19466；D-19466|||络铂
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. It is a platinum complex with DNA alkylating activity.
价 格：￥电议型 号：T15771产 地：中国大陆
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T15766Lirimilast；化合物 T15766BAY 19-8004；BAY 19-8004
Lirimilast is an effective, selective, and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 49 nM). Lirimilast has potently anti-inflammatory properties. Lirimilast can be used for the treatment of asthma or chronic obstructive pulmonary disease.
价 格：￥电议型 号：T15766产 地：中国大陆
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T15752Licogliflozin；化合物LicogliflozinLIK066；LIK066
Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).
价 格：￥电议型 号：T15752产 地：中国大陆
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T1574Etoricoxib；依托考昔Arcoxia|||MK-663|||Tauxib|||L-791456|||Nucoxia|||Desvenlafaxine；Arcoxia|||MK-663|||Ta
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
价 格：￥电议型 号：T1574产 地：中国大陆
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T15669KT5720；化合物 T15669KT5720
KT5720 is a cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (PKA) (Ki: 60 nM).
价 格：￥电议型 号：T15669产 地：中国大陆
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T15668KT185；化合物 T15668KT185
KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells).
价 格：￥电议型 号：T15668产 地：中国大陆
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T15667KRN4884；化合物 T15667KRN4884
KRN 4884 is an opener of the K+ channel. KRN 4884 (0.1-3 μM) activates KATP channels in a concentration-dependent manner (EC50=0.55 μM), in the presence of intracellular ATP (1 mM).
价 格：￥电议型 号：T15667产 地：中国大陆
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T15666KP136；化合物 KP136AL136；AL136
KP136 (AL136) is an orally active anti-allergic compound that inhibits histamine release and is used in studies of asthma and allergic edema.
价 格：￥电议型 号：T15666产 地：中国大陆
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T15665KJ Pyr 9；化合物KJ Pyr 9KJ Pyr 9
KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).
价 格：￥电议型 号：T15665产 地：中国大陆
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T15664KIRA-7；化合物 T15664KIRA-7
KIRA-7 is an imidazopyrazine compound. KIRA-7 has an anti-fibrotic effect. KIRA-7 binds the IRE1α kinase (IC50: 110 nM) to allosterically inhibit its RNase activity.
价 格：￥电议型 号：T15664产 地：中国大陆
