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T1666LFludrocortisone;氟氢可的松9α-fluorocortisol|||9α-Fludrocortisone|||Florinef|||9α-fluorohydrocortisone|||F
Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. Fludrocortisone can be used to studies on treating low blood pressure.
价 格:¥电议型 号:T1666L产 地:中国大陆
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T16669PRX-08066;化合物PRX-08066PRX-08066
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
价 格:¥电议型 号:T16669产 地:中国大陆
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T16668PROTO-1;化合物 T16668PROTO-1
PROTO-1 displays obviously protection of hair cells, with HC50(concentration that would produce 50% hair cell survival) of 1 μM-10 μM (1 μM≤HC50≤10 μM).
价 格:¥电议型 号:T16668产 地:中国大陆
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T16667PROTAC Sirt2 Degrader-1;化合物 T16667PROTAC Sirt2 Degrader-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s > 100 μM)[1].
价 格:¥电议型 号:T16667产 地:中国大陆
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T16666NH2-PEG3-C1-Boc化合物 T16666PROTAC Linker 5
NH2-PEG3-C1-Boc, also known as PROTAC Linker 5, is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T16666产 地:中国大陆
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T16665Triethylene glycol;化合物 T16665PROTAC Linker 25;PROTAC Linker 25
Triethylene glycol (PROTAC Linker 25) is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T16665产 地:中国大陆
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T16664N3-PEG4-C2-NH2化合物 T16664PROTAC Linker 20
N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based linker compound utilized for the synthesis of PROTACs. Its chemical structure enables efficient conjugation and serves as a bridging element between the target protein and the E3 ligase, facilitating targeted protein degradation[1].
价 格:¥电议型 号:T16664产 地:中国大陆
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T16663Bis-NH2-PEG2;化合物 T16663PROTAC Linker 19;PROTAC Linker 19
Bis-NH2-PEG2 (PROTAC Linker 19) is a PEG-based linker compound utilized for the synthesis of PROTACs.
价 格:¥电议型 号:T16663产 地:中国大陆
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T16662Tetraethylene glycol三缩四乙二醇PROTAC Linker 18|||三缩四乙二醇
Tetraethylene glycol (PROTAC Linker 18) is a polyethylene glycol (PEG)-based linker that finds utility in the synthesis of PROTACs[1].
价 格:¥电议型 号:T16662产 地:中国大陆
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T16661NH2-PEG5-C2-NH-Boc;化合物 T16661PROTAC Linker 17;PROTAC Linker 17
NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based compound utilized as a linker in the synthesis of PROTACs[1].
价 格:¥电议型 号:T16661产 地:中国大陆
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T16660N3-PEG3-CH2COOH;化合物 T16660N-3-PEG3-CH2COOH|||N3 PEG3 CH2COOH|||PROTAC Linker 14|||N3-PEG3-CH2COOH|||
N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based compound utilized for the synthesis of PROTACs.
价 格:¥电议型 号:T16660产 地:中国大陆
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T1666Fludrocortisone acetate;醋酸氟氢可的松9α-Fluorcortisol acetate|||9α-Fludrocortisone acetate|||9α-fluorocort
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Fludrocortisone acetate is the acetate salt of a synthetic fluorinated corticosteroid with anti-inflammatory and antiallergic activities. Inhibition of PLA2 activity prevents the release of arachidonic acid, a pre
价 格:¥电议型 号:T1666产 地:中国大陆
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T16659Boc-NH-PEG2-C2-NH2;化合物 T16659PROTAC Linker 13;PROTAC Linker 13
Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based linker utilized for the synthesis of PROTACs. This chemical compound plays a crucial role in connecting the targeted protein and the E3 ubiquitin ligase for selective protein degradation[1].
价 格:¥电议型 号:T16659产 地:中国大陆
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T16658Boc-NH-PEG4;化合物 T16658PROTAC Linker 12;PROTAC Linker 12
Boc-NH-PEG4, also known as PROTAC Linker 12, is a PEG-based linker compound utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T16658产 地:中国大陆
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T16657Boc-NH-PEG2化合物 T16657PROTAC Linker 11
Boc-NH-PEG2 (PROTAC Linker 11) is a polyethylene glycol (PEG)-based linker that finds application in the synthesis of PROTACs. [1]
价 格:¥电议型 号:T16657产 地:中国大陆
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T16656Propynol Ethoxylate;化合物 T16656Propynol Ethoxylate
Propynol Ethoxylate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16656产 地:中国大陆
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T16655Propargyl-PEG9-OH;化合物 T16655Propargyl-PEG9-OH
Propargyl-PEG9-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16655产 地:中国大陆
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T16654Propargyl-PEG9-bromide;化合物 T16654Propargyl-PEG9-bromide
Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16654产 地:中国大陆
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T16653Propargyl-PEG9-amine;化合物 T16653Propargyl-PEG9-amine
Propargyl-PEG9-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T16653产 地:中国大陆
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T16652Propargyl-PEG8-OH;化合物 T16652Propargyl-PEG8-OH
Propargyl-PEG8-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16652产 地:中国大陆