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已选条件
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T18166m-PEG24-alcohol;化合物 T18166m-PEG24-alcohol
m-PEG24-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18166产 地:中国大陆
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T18066Lenalidomide-OH;化合物Lenalidomide-OHLenalidomide-OH
Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. An example of a PROTAC BTK degrader incorporating Lenalidomide-OH is SJF620.
价 格:¥电议型 号:T18066产 地:中国大陆
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T17966Fmoc-NH-PEG11-CH2COOH;化合物 T17966Fmoc-NH-PEG11-CH2COOH
Fmoc-NH-PEG11-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17966产 地:中国大陆
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T17866DSPE-PEG5-propargyl;化合物 T17866DSPE-PEG5-propargyl
DSPE-PEG5-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17866产 地:中国大陆
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T17766DBCO-NHCO-PEG2-maleimide;化合物 T17766DBCO-NHCO-PEG2-maleimide
DBCO-NHCO-PEG2-maleimide is a polyethylene glycol (PEG) derived PROTAC linker utilized during PROTAC synthesis[1].
价 格:¥电议型 号:T17766产 地:中国大陆
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T17669Boc-NH-PEG12-propargyl;化合物 T17669Boc-NH-PEG12-propargyl
Boc-NH-PEG12-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17669产 地:中国大陆
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T17668Boc-NH-PEG12-NH2;叔丁氧羰基十二聚乙二醇氨基NHBoc-PEG12-amine;叔丁氧羰基十二聚乙二醇氨基|||NHBoc-PEG12-amine
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17668产 地:中国大陆
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T17667Boc-NH-PEG12-CH2CH2COOH叔丁氧羰基十二聚乙二醇羧乙基叔丁氧羰基十二聚乙二醇羧乙基
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17667产 地:中国大陆
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T17666Boc-NH-PEG11-OH叔丁氧羰基十一聚乙二醇羟基叔丁氧羰基十一聚乙二醇羟基
Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17666产 地:中国大陆
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T17665Boc-NH-PEG11-NH2;化合物Boc-NH-PEG11-NH2Boc-NH-PEG11-NH2
Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17665产 地:中国大陆
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T17664Boc-NH-PEG11-CH2CH2N3;化合物 T17664Boc-NH-PEG11-CH2CH2N3
Boc-NH-PEG11-CH2CH2N3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17664产 地:中国大陆
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T17663Boc-NH-PEG10-NHS ester;化合物 T17663Boc-NH-PEG10-NHS ester
Boc-NH-PEG10-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17663产 地:中国大陆
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T17662Boc-NH-PEG10-CH2CH2NH2;化合物 T17662Boc-NH-PEG10-CH2CH2NH2
Boc-NH-PEG10-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17662产 地:中国大陆
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T17661Boc-NH-PEG10-CH2CH2COOH;化合物 T17661Boc-NH-PEG10-CH2CH2COOH
Boc-NH-PEG10-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker utilized for PROTAC synthesis[1].
价 格:¥电议型 号:T17661产 地:中国大陆
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T17660Boc-NH-PEG1-Ph-O-CH2COOH;化合物 T17660Boc-NH-PEG1-Ph-O-CH2COOH
Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC[1].
价 格:¥电议型 号:T17660产 地:中国大陆
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T1766Empagliflozin恩格列净BI 10773|||恩格列净
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T1766产 地:中国大陆
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T1762RGFP966;化合物RGFP 966RGFP 966;RGFP 966
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.
价 格:¥电议型 号:T1762产 地:中国大陆
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T17566Biotin-PEG2-CH2CH2N3;化合物Biotin-PEG2-CH2CH2N3Biotin-PEG2-CH2CH2N3
Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17566产 地:中国大陆
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T17543BI-3663;化合物 T17543BI-3663
BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-4464 linked to Pomalidomide with a linker[1]. Anti-cancer activity[1].
价 格:¥电议型 号:T17543产 地:中国大陆
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T17466Azide-PEG16-alcohol;化合物 T17466Azide-PEG16-alcohol
Azide-PEG16-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17466产 地:中国大陆