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T15376GDC-0339；化合物GDC-0339GDC-0339
GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively).
价 格：￥电议型 号：T15376产 地：中国大陆
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T15276Ferroquine；二茂铁氯喹SSR97193|||Ferrochloroquine；SSR97193|||Ferrochloroquine
Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on Plasmodium.
价 格：￥电议型 号：T15276产 地：中国大陆
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T15214Emicerfont；化合物 T15214GW876008；GW876008
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
价 格：￥电议型 号：T15214产 地：中国大陆
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T15176DSS Crosslinker；双琥珀酰亚胺辛二酸酯DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.
价 格：￥电议型 号：T15176产 地：中国大陆
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T15076DBCO-S-S-PEG3-biotin生物素-PEG3-二硫-DBCO生物素-PEG3-二硫-DBCO
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label. PEG Linkers can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T15076产 地：中国大陆
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T15055DB04760；化合物 DB04760MMP-13 Inhibitor；MMP-13 Inhibitor
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.
价 格：￥电议型 号：T15055产 地：中国大陆
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T15013CS476；化合物 T15013NSC302998；NSC302998
CS476 is a potent drug of hypoglycaemic.
价 格：￥电议型 号：T15013产 地：中国大陆
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T14976CKD-519；化合物 T14976CKD-519
CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM).
价 格：￥电议型 号：T14976产 地：中国大陆
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T14947CHDI-390576；化合物 CHDI-390576CHDI-390576
CHDI-390576 is a CNS-permeable, selective and potent dibenzoyl isohydroxamic acid class IIa histone deacetylase (HDAC) inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, HDAC 9, and can be used in cancer research.
价 格：￥电议型 号：T14947产 地：中国大陆
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T14945CH-0793076；化合物 T14945TP3076；TP3076
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM).
价 格：￥电议型 号：T14945产 地：中国大陆
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T14925Cenisertib；化合物 T14925AS-703569|||R-763；AS-703569|||R-763
Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
价 格：￥电议型 号：T14925产 地：中国大陆
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T14908CCT367766；化合物CCT367766CCT367766
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low conc
价 格：￥电议型 号：T14908产 地：中国大陆
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T14876Carotegrast化合物 T14876Carotegrast
Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.
价 格：￥电议型 号：T14876产 地：中国大陆
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T14776BRD4 Inhibitor-10；化合物BRD4 Inhibitor-10BRD4 Inhibitor-10
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
价 格：￥电议型 号：T14776产 地：中国大陆
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T1476LPramipexole dihydrochloride；盐酸普拉克索Pramipexole dihydrochloride
Pramipexole dihydrochloride could be used to treat Parkinson disease.
价 格：￥电议型 号：T1476L产 地：中国大陆
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T14769Br-PEG3-CH2COOH；化合物 T14769BrPEG3CH2COOH|||Br PEG3 CH2COOH|||Br-PEG-3-CH2COOH|||Br-PEG3-CH2COOH；BrPEG
Br-PEG3-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14769产 地：中国大陆
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T14768Br-PEG3-C2-Boc；化合物 T14768Br-PEG3-C2-Boc
Br-PEG3-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14768产 地：中国大陆
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T14767BP 897 hydrochloride；化合物BP 897 hydrochlorideBP 897 hydrochloride
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格：￥电议型 号：T14767产 地：中国大陆
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T14766BPH-715；化合物BPH-715BPH-715
BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.
价 格：￥电议型 号：T14766产 地：中国大陆
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T14765BOS-172722；化合物BOS-172722BOS-172722
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
价 格：￥电议型 号：T14765产 地：中国大陆
