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T14763BoNT-IN-1；化合物 T14763BoNT-IN-1
BoNT-IN-1 is a potent Botulinum neurotoxin A light chain (BoNTA LC) inhibitor(IC50 : 0.9 uM).
价 格：￥电议型 号：T14763产 地：中国大陆
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T14762Boc-PEG4-sulfonic acid；化合物 T14762Boc-PEG4-sulfonic acid
Boc-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14762产 地：中国大陆
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T14760Boc-PEG2-sulfonic acid；化合物 T14760Boc-PEG2-sulfonic acid
Boc-PEG2-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14760产 地：中国大陆
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T1476Pramipexole；普拉克索SND 919；SND 919|||普拉克索
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not been implicated in cases of clinically apparent acute liver injury.
价 格：￥电议型 号：T1476产 地：中国大陆
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T14676BMS-688521化合物 BMS-688521BMS688521|||BMS 688521
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity.
价 格：￥电议型 号：T14676产 地：中国大陆
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T14576Biotin-C5-NHS Ester；化合物 T14576Biotin-C5-NHS Ester
Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1].
价 格：￥电议型 号：T14576产 地：中国大陆
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T14565BI-671800；化合物BI-671800AP-761|||Cmpd A；AP-761|||Cmpd A
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].
价 格：￥电议型 号：T14565产 地：中国大陆
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T14476Azido-PEG8-Boc；化合物 T14476Azido-PEG8-Boc
Azido-PEG8-Boc is a polyethylene glycol (PEG) and alkyl/ether-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T14476产 地：中国大陆
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T14382AZD7687；化合物 T14382AZD7687
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concentration-effect relationship [2]. Postprandial serum TAG excursion was measured during 8 h after a standardized mixed meal with fat energy content of 60% (SMM 60%; five cohorts, 1-20 mg), before (baseline) and after dosing, to assess effects on gu
价 格：￥电议型 号：T14382产 地：中国大陆
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T14381AZD7624；化合物AZD7624AZD-7624；AZD-7624
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
价 格：￥电议型 号：T14381产 地：中国大陆
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T14376AZD4320；化合物AZD4320AZD4320
AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively.
价 格：￥电议型 号：T14376产 地：中国大陆
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T14343Atreleuton；化合物 T14343ABT-761|||VIA-2291；ABT-761|||VIA-2291
Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity.
价 格：￥电议型 号：T14343产 地：中国大陆
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T14276Aminooxy-PEG5-azide；化合物 T14276Aminooxy-PEG5-azide
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
价 格：￥电议型 号：T14276产 地：中国大陆
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T14213Tapotoclax；化合物 T14213AMG-176；AMG-176
AMG-176 is a MCL-1 inhibitor (Ki: 0.13 nM).
价 格：￥电议型 号：T14213产 地：中国大陆
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T14176Aleglitazar；阿格列扎RO0728804|||R1439；RO0728804|||R1439
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes.
价 格：￥电议型 号：T14176产 地：中国大陆
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T14146AGN 210676；化合物 T14146Simenepag；Simenepag
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
价 格：￥电议型 号：T14146产 地：中国大陆
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T14076A 839977；化合物A 839977A839977|||A-839977；A839977|||A-839977
A 839977 is a selective P2X7 receptor antagonist with anti-inflammatory and analgesic activity that inhibits BzATP-induced calcium efflux from the P2X7 receptor for the study of renal fibrosis.
价 格：￥电议型 号：T14076产 地：中国大陆
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T13976(Arg)9；化合物 T13976Peptide R9|||Nona-L-arginine；Peptide R9|||Nona-L-arginine
(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).
价 格：￥电议型 号：T13976产 地：中国大陆
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T13908SZ1676；化合物 T13908SZ1676
SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.
价 格：￥电议型 号：T13908产 地：中国大陆
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T13876(S,R,S)-AHPC-propargyl；化合物 T13876(S,R,S) AHPC propargyl|||VHL ligand 7|||AHPC-propargyl|||VH032-prop
(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs.
价 格：￥电议型 号：T13876产 地：中国大陆
