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  • T16566Propyl pyrazole triol;化合物Propyl pyrazole triolPPT;PPT

    Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).

    价 格:¥电议型 号:T16566产 地:中国大陆

  • T16565Ppc-1;化合物 T16565Ppc-1

    Ppc-1 is a chemical compound known for its inhibitory effects on the Gram-negative periodontopathogen Porphyromonas gingivalis. It acts as a mitochondrial uncoupler, enhancing mitochondrial oxygen consumption without affecting ATP production. Additionally, Ppc-1 serves as a cell-permeate inhibitor of interleukin-2 (IL-2). This compound exhibits various beneficial activities, including anti-obesity, antibacterial, and anti-inflammatory properties.

    价 格:¥电议型 号:T16565产 地:中国大陆

  • T16564PPADS tetrasodium;化合物PPADS四钠盐PPADS tetrasodium

    PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca?? exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma inhibits P2X1, P2X-2, P2X-3, and P2X- 5. 5.

    价 格:¥电议型 号:T16564产 地:中国大陆

  • T16563LPozanicline hydrochloride;化合物Pozanicline hydrochloridePozanicline hydrochloride

    Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAChR with a Ki of 17 nM while binding to α7 nAChR is insignificant[2].

    价 格:¥电议型 号:T16563L产 地:中国大陆

  • T16563Pozanicline;化合物 T16563ABT-089;ABT-089

    Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM). It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .

    价 格:¥电议型 号:T16563产 地:中国大陆

  • T16562Ponceau 4R胭脂红Acid Red 18|||New Coccine

    Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usually synthesized from aromatic hydrocarbons.

    价 格:¥电议型 号:T16562产 地:中国大陆

  • T16561Polyoxyethylene stearate;聚氧乙烯硬脂酸酯POES;POES|||聚氧乙烯硬脂酸酯

    Polyoxyethylene stearate (POES) is an agent of non-ionic emulsifying.

    价 格:¥电议型 号:T16561产 地:中国大陆

  • T16560Poloxin;化合物PoloxinPoloxin

    Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).

    价 格:¥电议型 号:T16560产 地:中国大陆

  • T1656Vandetanib凡德他尼ZD6474|||凡德他尼

    Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.

    价 格:¥电议型 号:T1656产 地:中国大陆

  • T16559Poloxime;化合物 T16559Poloxime

    Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity.

    价 格:¥电议型 号:T16559产 地:中国大陆

  • T16558Polidocanol聚多卡醇Polyoxyethylene lauryl ether|||Polyoxyethyleneglycol Dodecyl Ether

    Polidocanol (Polyoxyethylene lauryl ether) is an alkyl polyethylene glycol ether of lauryl alcohol, which is a derivative of natural fatty or alkyl alcohols in natural mineral oil and is a hardener. Polidocanol can be used as a local anesthetic, but in combination with other anesthetic drugs there is a risk of enhancing the effects of the anesthetic drugs on the cardiovascular system.

    价 格:¥电议型 号:T16558产 地:中国大陆

  • T16557PNU-159682;化合物PNU-159682PNU-159682

    PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.

    价 格:¥电议型 号:T16557产 地:中国大陆

  • T16556PNU-142633化合物 T16556PNU 142633|||PNU142633

    PNU-142633 has anti-migraine efficacy. PNU-142633 is a high affinity and selective 5-HT1D receptor agonist (Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively).

    价 格:¥电议型 号:T16556产 地:中国大陆

  • T16555PNU-103017;化合物 T16555PNU-103017

    PNU-103017 is an inhibitor of HIV protease.

    价 格:¥电议型 号:T16555产 地:中国大陆

  • T16554PNPP;4-硝基苯磷酸二钠PNPP

    PNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

    价 格:¥电议型 号:T16554产 地:中国大陆

  • T16553Pneumadin, rat;化合物 T16553PNM;PNM

    Pneumadin, rat (PNM) exerts a marked antidiuretic effect in animals has a functional AVP system. Pneumadin, rat (PNM) is a decapeptide, which possesses a potent stimulating effect on arginine-vasopressin (AVP) release.

    价 格:¥电议型 号:T16553产 地:中国大陆

  • T16552Pleuromutilin;截短侧耳素Mutilin 14-glycolate|||Drosophilin B;Mutilin 14-glycolate|||Drosophilin B|||截短侧耳素

    Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.

    价 格:¥电议型 号:T16552产 地:中国大陆

  • T16551Pladienolide B;普拉地内酯BPladienolide B

    Pladienolide B is a potent spliceosome inhibitor, a macrolide isolated from Streptomyces obtusususus Mer-12, which targets the SF3B1 subunit of the spliceosome.Pladienolide B exerts its antitumor effects by inhibiting pre-mRNA splicing and inducing necrosis.Pladienolide B possesses antitumor activity and can be used to study leukemia and lymphoid tumors. Pladienolide B has antitumor activity and can be used to study leukemia and lymphoid tumors.

    价 格:¥电议型 号:T16551产 地:中国大陆

  • T16550PKR-IN-C16;化合物PKR-IN-C16PKR-IN-C16

    PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

    价 格:¥电议型 号:T16550产 地:中国大陆

  • T1655Ambrisentan;安倍生坦BSF-208075|||BSF 208075|||LU 208075;BSF-208075|||BSF 208075|||安倍生坦|||LU 208075

    Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but has yet to be implicated in cases of clinically apparent acute liver injury.

    价 格:¥电议型 号:T1655产 地:中国大陆

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