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  • T80056Glutathione Peroxidase；化合物 Glutathione PeroxidaseGSH-Px|||EC 1.11.1.9；GSH-Px|||EC 1.11.1.9

    Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (GSSG) by forming a disulfide bridge, concurrently reducing hydrogen peroxide or lipid peroxides to water. This enzyme serves as a potent antioxidant, protecting against oxidative stress [1].

    价 格：￥电议型 号：T80056产 地：中国大陆

  • T7948HPGDS inhibitor 2化合物GSK-2894631AGSK-2894631A

    HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.

    价 格：￥电议型 号：T7948产 地：中国大陆

  • T79474GSPT1 degrader-1；化合物 GSPT1 degrader-1GSPT1 degrader-1

    GSPT1 Degrader-1 (Compound 9q) effectively facilitates the degradation of G1 to S phase transition 1 (GSPT1) through the ubiquitin-proteasome system and induces G0/G1 phase arrest and apoptosis in cells [1].

    价 格：￥电议型 号：T79474产 地：中国大陆

  • T79021GSK3839919A；化合物 GSK3839919AGSK3839919A

    GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].

    价 格：￥电议型 号：T79021产 地：中国大陆

  • T79018GSK217；化合物 GSK217GSK217

    GSK217 is a potent and selective inhibitor of the bromo and extraterminal domain (BET) second bromodomain (BD2) with high solubility, utilized in oncology and immune inflammation research [1].

    价 格：￥电议型 号：T79018产 地：中国大陆

  • T79017GSK737；化合物 GSK737GSK737

    GSK737 is a dual inhibitor of BRD4 BD1 and BD2, exhibiting pIC50 values of 5.3 and 7.3, respectively. It demonstrates low clearance, along with favorable solubility and permeability in rats [1].

    价 格：￥电议型 号：T79017产 地：中国大陆

  • T78874GSK-3β inhibitor 15；化合物 GSK-3β inhibitor 15GSK-3β inhibitor 15

    GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-induced iNOS expression. It demonstrates neuroprotective properties against Aβ 1-42-induced neurotoxicity, indicating its potential utility in Alzheimer´s disease (AD) research [1].

    价 格：￥电议型 号：T78874产 地：中国大陆

  • T78800GST-IN-1；化合物 GST-IN-1GST-IN-1

    GST-IN-1, also known as compound 16, is a potent inhibitor of glutathione S-transferase (GST), exhibiting inhibitory concentration 50 (IC50) values of 1.55 μM for sjGST and 2.02 μM for hGSTM2.

    价 格：￥电议型 号：T78800产 地：中国大陆

  • T78578GSK-3 Inhibitor XIII；GSK-3抑制剂XIIIGSK-3 Inhibitor XIII

    GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.

    价 格：￥电议型 号：T78578产 地：中国大陆

  • T77903Belantamab mafodotin；化合物 Belantamab mafodotinBelantamab mafodotin-blm|||GSK2857916；Belantamab mafodo

    Belantamab mafodotin (GSK2857916) is a conjugate of a humanized, targeted monoclonal antibody directed against the B cell maturation antigen (BCMA) and the cytotoxic agent McMMAF, exhibiting anti-myeloma activity [1] [2].

    价 格：￥电议型 号：T77903产 地：中国大陆

  • T77671GSK3a-IN-38；GSK3a抑制剂38GSK3a-IN-38

    GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.

    价 格：￥电议型 号：T77671产 地：中国大陆

  • T7766Remdesivir；瑞德西韦GS-5734；瑞德西韦|||GS-5734

    Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viruses, and is potentially therapeutic against COVID-19.

    价 格：￥电议型 号：T7766产 地：中国大陆

  • T77554GSK-3 Inhibitor 5；化合物 GSK-3 Inhibitor 54-Cyanophenacyl bromide；4-Cyanophenacyl bromide

    GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) is a ketone derivative that is used as an intermediate in pharmaceuticals and organic synthesis, and inhibits glycogen synthase kinase 3 (GSK-3).

    价 格：￥电议型 号：T77554产 地：中国大陆

  • T77433Feladilimab；菲阿迪利单抗GSK3359609；GSK3359609

    Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L1 expression. Feladilimab has anti-tumor activity and can be used to study cancer.

    价 格：￥电议型 号：T77433产 地：中国大陆

  • T77342GSK-3 inhibitor 3；GSK-3抑制剂3GSK-3 inhibitor 3

    GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively.GSK-3 inhibitor 3 reduces the phosphorylation level of tau protein S396 with an IC50 of 10 nM in a triple transgenic mouse model of Alzheimer´s disease. GSK-3 inhibitor 3 reduced the phosphorylation level of tau protein S396 in a triple transgenic mouse model of Alzheimer´s disease, with an IC50 of 10 nM.GSK-3 inhibitor 3 can

    价 格：￥电议型 号：T77342产 地：中国大陆

  • T77341GSK-3 inhibitor 4；GSK-3抑制剂4GSK-3 inhibitor 4

    GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with IC50 values of 0.56 nM, 0.45 nM, 0.47 μM, 0.68 μM, respectively.GSK-3 inhibitor 4 can effectively reduce Tau protein levels. GSK-3 inhibitor 4 can effectively reduce the level of Tau protein.GSK-3 inhibitor 4 can be used in the study of Alzheimer´s disease.

    价 格：￥电议型 号：T77341产 地：中国大陆

  • T77149Cobolimab考伯利单抗TSR-022|||GSK4069889

    Cobolimab (TSR-022) is a potent monoclonal antibody to TIM-3. Cobolimab induces internalization of TIM-3 with an IC50 value of 0.4464 nM. Cobolimab has antitumor activity and can be used to study advanced/metastatic melanoma and advanced hepatocellular carcinoma.

    价 格：￥电议型 号：T77149产 地：中国大陆

  • T77129Belantamab；贝兰妥单抗GSK2857914；GSK2857914

    Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantamab mafodotin).

    价 格：￥电议型 号：T77129产 地：中国大陆

  • T77125Otilimab；Otilimab单抗GSK 3196165|||MOR103；GSK 3196165|||MOR103

    Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.

    价 格：￥电议型 号：T77125产 地：中国大陆

  • T7709(E/Z)-GSK5182；化合物GSK5182(Z/E)GSK5182(Z/E)；GSK5182(Z/E)

    (E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.

    价 格：￥电议型 号：T7709产 地：中国大陆

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