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T77053Latozinemab；单抗LatozinemabGSK-4527223|||AL-001；GSK-4527223|||AL-001
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interrupts the interaction between the granule protein precursor (PGRN) and the Sortilin receptor.Latozinemab can be used to study of dementia and Alzheimer´s disease.
价 格：￥电议型 号：T77053产 地：中国大陆
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T76856Andecaliximab；Andecaliximab单抗GS-5745；GS-5745
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model of idiopathic pulmonary fibrosis. Andecaliximab can be used to study gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF), as well as dengue virus.
价 格：￥电议型 号：T76856产 地：中国大陆
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T76815Lexatumumab来沙木单抗ETR2-ST01|||DR5 mAB|||HGS-ETR 2
Lexatumumab (GHS-ETR 2) is a human excitatory monoclonal antibody targeting TRAIL receptor 2 that has anticancer activity and induces apoptosis in malignant mesothelioma. Lexatumumab can be used to study malignant pleural mesothelioma (MPM).
价 格：￥电议型 号：T76815产 地：中国大陆
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T7680GSNKGAIIGLM(131602-53-4(free base))；BETA-淀粉样蛋白片断25-35Amyloid beta-peptide(25-35)；Amyloid beta-peptid
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer´s amyloid β-peptide.
价 格：￥电议型 号：T7680产 地：中国大陆
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T76700Simtuzumab；辛妥珠单抗GS 6624|||AB 0024；GS 6624|||AB 0024
Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.
价 格：￥电议型 号：T76700产 地：中国大陆
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T76450Substance P-Gly-Lys-Arg；化合物 Substance P-Gly-Lys-ArgSubstance P-Gly-Lys-Arg
Substance P-Gly-Lys-Arg, also referred to as β-Preprotachykinin (58-71), is an analog of Substance P.
价 格：￥电议型 号：T76450产 地：中国大陆
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T76252LWLSEAGPVVTVRALRGTGSW TFA；化合物 WLSEAGPVVTVRALRGTGSW TFAWLSEAGPVVTVRALRGTGSW TFA
WLSEAGPVVTVRALRGTGSW TFA, a cardiomyocyte-specific peptide, exhibits enhanced performance through its expression in exosomes, which notably improves uptake by cardiomyocytes, reduces apoptosis within these cells, and increases cardiac retention after intramyocardial injection in vivo [1] [2].
价 格：￥电议型 号：T76252L产 地：中国大陆
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T76250LVSGLNPSLWSIFGLQFILLWLVSGSRHYLW TFA；化合物 VSGLNPSLWSIFGLQFILLWLVSGSRHYLW TFAVSGLNPSLWSIFGLQFILLWLVSGSRH
VSGLNPSLWSIFGLQFILLWLVSGSRHYLW (TFA), a 30-amino-acid peptide, mimics the C-terminal domain of α2δ-1, known as α2δ-1Tat peptide. This compound disrupts the α2δ-1 - NMDAR interaction both in vitro and in vivo, demonstrating potential utility in neuropathic pain research [1].
价 格：￥电议型 号：T76250L产 地：中国大陆
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T76250VSGLNPSLWSIFGLQFILLWLVSGSRHYLW；化合物 VSGLNPSLWSIFGLQFILLWLVSGSRHYLWVSGLNPSLWSIFGLQFILLWLVSGSRHYLW
VSGLNPSLWSIFGLQFILLWLVSGSRHYLW, a 30-amino-acid peptide, mirrors the C-terminal domain of α2δ-1 and is recognized as the α2δ-1Tat peptide. It disrupts the α2δ-1 - NMDAR interaction both in vitro and in vivo, offering a potential research tool for neuropathic pain studies [1].
价 格：￥电议型 号：T76250产 地：中国大陆
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T76201LEESGGGLVQPGGSMK TFA；化合物 LEESGGGLVQPGGSMK TFALEESGGGLVQPGGSMK TFA
LEESGGGLVQPGGSMK TFA, a proteolysis peptide component of Infliximab, serves for the quantitative analysis of the latter. Infliximab is a chimeric monoclonal IgG1 antibody, binding specifically to TNF-α [1].
价 格：￥电议型 号：T76201产 地：中国大陆
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T76088GSK3 Substrate, α, β subunit；化合物 GSK3 Substrate, α, β subunitGSK3 Substrate, α, β subunit
GSK3 Substrate, α, β subunit, serves as a peptide substrate for Glycogen Synthase Kinase-3 (GSK-3), facilitating the measurement of GSK-3 activity [1].
价 格：￥电议型 号：T76088产 地：中国大陆
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T75562Ganoderic acid GS-1；化合物 Ganoderic acid GS-1Ganoderic acid GS-1
Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].
价 格：￥电议型 号：T75562产 地：中国大陆
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T7556Fadrozole hydrochloride；盐酸法倔唑CGS 16949A；CGS 16949A|||盐酸法倔唑
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
价 格：￥电议型 号：T7556产 地：中国大陆
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T75241Ledipasvir hydrochloride；盐酸雷迪帕韦GS-5885 hydrochloride；GS-5885 hydrochloride
Ledipasvir hydrochloride (GS-5885) is a hepatitis C virus NS5A inhibitor, displaying potent activity with EC50 values of 34 pM for genotype 1a replicon and 4 pM for genotype 1b replicon. Additionally, it acts as a SARS-CoV 3CL pro inhibitor with an IC50 of 1.62 ?M [3].
价 格：￥电议型 号：T75241产 地：中国大陆
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T74887GSK3735967；化合物 GSK3735967GSK3735967
GSK3735967 is a selective, reversible, non-nucleoside inhibitor targeting DNMT1, demonstrating an IC50 value of 40 nM. It features a planar dicyanopyridine core designed to specifically interact with DNMT1-bound hemimethylated CpG dinucleotides. Additionally, GSK3735967 possesses three binding sites, with one uniquely capable of binding to histone H4K20me3 [1] [2].
价 格：￥电议型 号：T74887产 地：中国大陆
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T74658HBPC–GSH；化合物 HBPC–GSHHBPC–GSH
HBPC-GSH, a derivative of glutathione, functions as an inhibitor for the glyoxalase system, specifically inhibiting cGloI and cGloII with IC50 values of 0.6μM and 1.6μM, respectively. This compound is utilized in antimalarial research [1].
价 格：￥电议型 号：T74658产 地：中国大陆
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T74558SK-575-NEG；化合物 SK-575-NEGSK-575-NEG
SK-575-NEG (compound 28), a methylated derivative of SK-575, results from the methylation of the piperidine-2,6-dione´s amino group in SK-575, serving as a control compound. It exhibits strong binding affinity to PARP1, evidenced by an IC50 of 2.64 nM. However, SK-575-NEG proved to be ineffective in promoting PARP1 degradation in MDA-MB-436 and Capan-1 cells, even at concentrations as high as 1 μM [1].
价 格：￥电议型 号：T74558产 地：中国大陆
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T74288SQDG；化合物 SQDGSQDG
SQDG, a membrane glycolipid characterized by sugar moieties in its head groups, is instrumental in studying the influence of structural lipids in LNP formulations [1].
价 格：￥电议型 号：T74288产 地：中国大陆
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T73929(S,S)-GSK321；化合物 (S,S)-GSK321(S,S)-GSK321
(S,S)-GSK321 is a (S,S)-enantiomer of GSK321 [1] .
价 格：￥电议型 号：T73929产 地：中国大陆
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T7392Revefenacin；化合物RevefenacinTD-4208|||GSK1160724；TD-4208|||GSK1160724
Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.
价 格：￥电议型 号：T7392产 地：中国大陆
