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  • T78220SAMβA TFA;化合物 SAMβA TFASAMβA TFA

    SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improves heart failure outcomes in rats [1].

    价 格:¥电议型 号:T78220产 地:中国大陆

  • T78214FAP-IN-2 TFA;化合物 FAP-IN-2 TFAFAP-IN-2 TFA

    FAP-IN-2 TFA is a 99mTc-labeled, isonitrile-containing derivative inhibitor of fibroblast activation protein (FAP), utilized for tumor imaging [1].

    价 格:¥电议型 号:T78214产 地:中国大陆

  • T78179NH2-UAMC1110 TFA;化合物 NH2-UAMC1110 TFANH2-UAMC1110 TFA

    NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating agent crucial for creating radiotracers with high tumor selectivity and potency for tumor diagnosis and therapy [1] [2].

    价 格:¥电议型 号:T78179产 地:中国大陆

  • T78163JBSNF-000028 TFA;化合物 JBSNF-000028 TFAJBSNF-000028 TFA

    JBSNF-000028 TFA, a nicotinamide N-methyltransferase (NNMT) inhibitor, exhibits oral activity with inhibitory concentration 50 (IC50) values of 0.033 μM, 0.19 μM, and 0.21 μM for human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) respectively. It is applicable in metabolic disorder research [1].

    价 格:¥电议型 号:T78163产 地:中国大陆

  • T78147TP-5801 TFA;化合物 TP-5801 TFATP-5801 TFA

    TP-5801 TFA is an orally active inhibitor of TNK1, a non-receptor tyrosine kinase, with an IC50 value of 1.40 nM, demonstrating anti-tumor activity [1].

    价 格:¥电议型 号:T78147产 地:中国大陆

  • T78144NCGC00138783 TFA;化合物 NCGC00138783 TFANCGC00138783 TFA

    NCGC00138783 TFA acts as a selective inhibitor of the CD47/SIRPα axis, exhibiting an inhibitory concentration (IC50) of 50 μM. This compound effectively obstructs the interaction between CD47 and SIRPα [1] [2].

    价 格:¥电议型 号:T78144产 地:中国大陆

  • T78121SSM3 tetraTFA hydrate;化合物 SSM3 tetraTFA hydrateSSM3 tetraTFA hydrate

    SSM3 tetraTFA hydrate is a potent synthetic inhibitor of furin, exhibiting an EC50 of 54 nM and a Ki of 12 nM. It effectively inhibits the furin-dependent cell surface processing of anthrax protective antigen-83 in vitro [1] [2].

    价 格:¥电议型 号:T78121产 地:中国大陆

  • T78117FN-439 TFA;化合物 FN-439 TFAFN-439 TFA

    FN-439 TFA is a selective inhibitor of collagenase-1, exhibiting inhibition with an IC50 of 1 μM, and is utilized in cancer and inflammation research [1] [2].

    价 格:¥电议型 号:T78117产 地:中国大陆

  • T78110DOTA-LM3 TFA;化合物 DOTA-LM3 TFADOTA-LM3 TFA

    DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2. It is effectively used in tracing tumors in vivo through isotopic labeling, examples being 177Lu-DOTA-LM3 TFA and 68Ga-DOTA-LM3 TFA. The 68Ga-labeled compound demonstrates favorable biodistribution, high tumor uptake, good tumor retention, and minimal safety concerns. Meanwhile, the 177Lu-labeled variant is utilized in research targeting

    价 格:¥电议型 号:T78110产 地:中国大陆

  • T78109(Ala13)-Apelin-13 TFA;化合物 (Ala13)-Apelin-13 TFA(Ala13)-Apelin-13 TFA

    ´(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].´

    价 格:¥电议型 号:T78109产 地:中国大陆

  • T78107Reltecimod TFA;化合物 Reltecimod TFAAB-103 TFA;AB-103 TFA

    Reltecimod (AB-103) TFA is an antagonist of the T-cell-specific surface glycoprotein CD28 (TP44), demonstrating efficacy against various bacterial infections, including their exotoxins and endotoxins, as well as ionizing radiation. By modulating the inflammatory response through attenuation of the key CD28/B7-2 co-stimulatory pathway without full inhibition, Reltecimod TFA is utilized in researching necrotizing soft-tissue infections (NSTIs) [1].

    价 格:¥电议型 号:T78107产 地:中国大陆

  • T78106Kisspeptin 234 TFA;化合物 Kisspeptin 234 TFAKisspeptin 234 TFA

    Kisspeptin 234 TFA is a 10-amino acid peptide analog of Kisspeptin 10 [1] that functions as an antagonist to the kisspeptin receptor (KISS1, GPR54).

    价 格:¥电议型 号:T78106产 地:中国大陆

  • T78103Box5 TFA;化合物 Box5 TFABox5 TFA

    Box5 TFA, a potent Wnt5a antagonist, impedes Wnt5a signaling, restricts Wnt5a-initiated Ca2+ release, and hampers cell migration, showing promise for melanoma research applications [1].

    价 格:¥电议型 号:T78103产 地:中国大陆

  • T78098Survodutide TFA;化合物 Survodutide TFABI 456906 TFA;BI 456906 TFA

    Survodutide (BI 456906) (TFA) is a dual agonist of the glucagon and glucagon-like peptide 1 (GLP-1) receptors, and Survodutide (TFA) is synonymous with Survodutide[1].

    价 格:¥电议型 号:T78098产 地:中国大陆

  • T78063Endothelin-1 (1-31) (Human) TFA;化合物 Endothelin-1 (1-31) (Human) TFAEndothelin-1 (1-31) (Human) TFA

    Endothelin-1 (1-31) (Human) TFA, a potent vasoconstrictor and hypertensive agent, originates from the chymase-mediated selective hydrolysis of big ET-1 [1].

    价 格:¥电议型 号:T78063产 地:中国大陆

  • T78062Dendrotoxin K TFA;化合物 Dendrotoxin K TFADendrotoxin K TFA

    Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].

    价 格:¥电议型 号:T78062产 地:中国大陆

  • T78061Peptide5 TFA;化合物 Peptide5 TFAPeptide5 TFA

    Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it suppresses the NLRP3 inflammasome, functioning as an anti-inflammatory agent [1] [2] [3].

    价 格:¥电议型 号:T78061产 地:中国大陆

  • T78060ProTx II TFA;化合物 ProTx II TFAProTx II TFA

    ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2].

    价 格:¥电议型 号:T78060产 地:中国大陆

  • T78041Tat-peptide control 168-189 TFA;化合物 Tat-peptide control 168-189 TFATat-peptide control 168-189 TFA

    Tat-peptide 168-189, a cell-permeable, Tat-labeled fusion peptide derived from residues 168-189 of rat G3BP1, features the HIV Tat sequence at its least conserved terminus to enhance cellular uptake. It serves as the negative control for Tat-peptide 168-189 TFA, which promotes axon growth and neurite proliferation [1].

    价 格:¥电议型 号:T78041产 地:中国大陆

  • T78040Tat-peptide 190-208 TFA;化合物 Tat-peptide 190-208 TFATat-peptide 190-208 TFA

    Tat-peptide 190-208 TFA is a Tat-labeled, cell-permeable fusion peptide derived from residues 190-208 of rat G3BP1. The HIV-derived Tat sequence, positioned at the peptide´s least conserved region, confers cellular permeability. This compound promotes axon growth and enhances the formation of neurites per neuron, suggesting an axon intrinsic mechanism of action. Additionally, it has potential applications in providing ischemic protection during endovascular repair of intracranial aneurysms

    价 格:¥电议型 号:T78040产 地:中国大陆

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