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T77996iRGD peptide 1 TFA；化合物 iRGD peptide 1 TFAiRGD peptide 1 TFA
iRGD Peptide 1 TFA is a prototypic tumor-homing peptide with tissue-penetrating capabilities, facilitating deep delivery of therapeutic agents into extravascular tumor tissue. Additionally, it possesses anti-metastatic activity [1].
价 格：￥电议型 号：T77996产 地：中国大陆
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T77994Grb2 SH2 domain inhibitor 1 TFA；化合物 Grb2 SH2 domain inhibitor 1 TFAGrb2 SH2 domain inhibitor 1 TFA
Grb2 SH2 Domain Inhibitor 1 TFA is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R signifies D-arginine, and P stands for D-proline. It primarily functions as a cyclic peptide inhibitor.
价 格：￥电议型 号：T77994产 地：中国大陆
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T77992Goralatide TFA；化合物 Goralatide TFAGoralatide TFA
Goralatide TFA acts as an inhibitor of cell cycle progression and selectively enhances the hyperthermic purging of human progenitor cells, with potential application in leukemia research [1].
价 格：￥电议型 号：T77992产 地：中国大陆
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T77991Glutaurine TFA；化合物 Glutaurine TFALitoralon TFA；Litoralon TFA
Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in the study of antiepileptic and anti-amnesia treatments, as evidenced by references [1] [2] [3] [4].
价 格：￥电议型 号：T77991产 地：中国大陆
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T77969SIAIS100 TFA；化合物 SIAIS100 TFASIAIS100 TFA
SIAIS100 TFA is a potent BCR-ABL PROTAC degrader, exhibiting a DC50 of 2.7 nM. It is utilized in the research of chronic myeloid leukemia (CML) [1].
价 格：￥电议型 号：T77969产 地：中国大陆
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T77968MS15 TFA；化合物 MS15 TFAMS15 TFA
MS15 TFA is a potent, selective AKT PROTAC degrader, effectively inhibiting AKT1, AKT2, and AKT3 with IC50 values of 798 nM, 90 nM, and 544 nM, respectively [1].
价 格：￥电议型 号：T77968产 地：中国大陆
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T77947Tri-GalNAc(OAc)3 TFA；化合物 Tri-GalNAc(OAc)3 TFATri-GalNAc(OAc)3 TFA
Tri-GalNAc(OAc)3 TFA, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome-targeting chimera (GalNAc-LYTAC). This compound facilitates targeted protein degradation by engaging with the asialoglycoprotein receptor [1].
价 格：￥电议型 号：T77947产 地：中国大陆
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T77943SJ1008030 TFA；化合物 SJ1008030 TFASJ1008030 TFA
SJ1008030 (compound 8) TFA is a selective JAK2-degrading PROTAC that inhibits the growth of MHH-CALL-4 leukemia cells with an IC50 of 5.4 nM, indicating its potential use for leukemia research [1].
价 格：￥电议型 号：T77943产 地：中国大陆
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T77938JPS016 TFA；化合物 JPS016 TFAJPS016 TFA
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a substantial increase in differentially expressed genes and augmented apoptosis in HCT116 cells [1].
价 格：￥电议型 号：T77938产 地：中国大陆
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T77937JPS014 TFA；化合物 JPS014 TFAJPS014 TFA
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a higher number of differentially expressed genes and increased apoptosis in HCT116 cells [1].
价 格：￥电议型 号：T77937产 地：中国大陆
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T77932PF15 TFA；化合物 PF15 TFAPF15 TFA
PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM. The compound potently suppresses proliferation in FLT3-ITD-positive cells, reduces phosphorylation levels of FLT3 and STAT5, and demonstrates inhibition of tumor growth in murine leukemia models [1].
价 格：￥电议型 号：T77932产 地：中国大陆
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T77930Dovitinib-RIBOTAC TFA；化合物 Dovitinib-RIBOTAC TFADovitinib-RIBOTAC TFA
Dovitinib RIBOTAC TFA effectively and selectively cleaves pre-miR-21, functioning as a targeted RNA degrader.
价 格：￥电议型 号：T77930产 地：中国大陆
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T77923BSJ-03-204 triTFA；化合物 BSJ-03-204 triTFABSJ-03-204 triTFA
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring Palbociclib-based ligands for the degradation of CDK4/6. It exhibits IC50 values of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1, indicating strong inhibitory capabilities. Notably, it spares IKZF1/3 from degradation and possesses anti-cancer activity [1].
价 格：￥电议型 号：T77923产 地：中国大陆
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T77920ZXH-4-130 TFA；化合物 ZXH-4-130 TFAZXH-4-130 TFA
ZXH-4-130 TFA is a hetero-PROTAC (CRBN-VHL compound) that efficaciously and selectively mediates the degradation of CRBN. At a concentration of 10 nM in MM1.S cells, ZXH-4-130 TFA achieves approximately 80% degradation of CRBN [1].
价 格：￥电议型 号：T77920产 地：中国大陆
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T77913PZ703b TFA；化合物 PZ703b TFAPZ703b TFA
PZ703b TFA, a Bcl-xl PROTAC degradation agent, promotes apoptosis and halts bladder cancer cell proliferation, making it a pertinent investigative compound for related oncological studies [1] [2].
价 格：￥电议型 号：T77913产 地：中国大陆
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T77902Boc-Gly-Gly-Phe-Gly-OH TFA；化合物 Boc-Gly-Gly-Phe-Gly-OH TFABoc-Gly-Gly-Phe-Gly-OH TFA
Boc-Gly-Gly-Phe-Gly-OH TFA, an N- and C-protected tetrapeptide, functions as a protease-cleavable linker in antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T77902产 地：中国大陆
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T77889NH2-methylpropanamide-Exatecan TFA；化合物 NH2-methylpropanamide-Exatecan TFANH2-methylpropanamide-Exate
Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.975 μg/mL), utilized in the synthesis of ADCs for cancer research [1].
价 格：￥电议型 号：T77889产 地：中国大陆
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T77867Mal-PEG8-Phe-Lys-PAB-Exatecan TFA；化合物 Mal-PEG8-Phe-Lys-PAB-Exatecan TFAMal-PEG8-Phe-Lys-PAB-Exatecan
Mal-PEG8-Phe-Lys-PAB-Exatecan TFA is a conjugate for ADC comprised of the degradable linker Mal-PEG8-Phe-Lys-PAB and the cytotoxic agent Exatecan [1].
价 格：￥电议型 号：T77867产 地：中国大陆
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T77837CL2E-SN38 TFA；化合物 CL2E-SN38 TFACL2E-SN38 TFA
CL2E-SN-38 TFA, a structurally stable and highly releasable antibody drug conjugate (ADC), comprises SN-38, the active metabolite of Irinotecan derived from camptothecins, known for its Topoisomerase I inhibitory activity [1].
价 格：￥电议型 号：T77837产 地：中国大陆
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T77833Mc-Gly-Gly-Phe-Gly-PAB-OH TFA；化合物 Mc-Gly-Gly-Phe-Gly-PAB-OH TFAMc-GGFG-PAB-OH TFA；Mc-GGFG-PAB-OH TFA
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T77833产 地：中国大陆
