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T10563LBM635 hydrochloride (1493762-74-5 free base)；化合物 T10563LBM635 hydrochloride；BM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
价 格：￥电议型 号：T10563L产 地：中国大陆
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T10562(4-Acetamidocyclohexyl) nitrate；化合物 T10562BM121307；BM121307
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
价 格：￥电议型 号：T10562产 地：中国大陆
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T10560P2X3 antagonist 34；化合物 T10560BLU-5937；BLU-5937
P2X3 antagonist 34, a potent, selective, and orally active antagonist, targets the P2X3 homotrimeric receptor, exhibiting IC50s of 25 nM, 92 nM, and 126 nM for human, rat, and guinea pig P2X3 receptors respectively. It shows reduced activity against P2X2/3 heterotrimeric receptors across human, rat, and guinea pig models. Notably, this compound demonstrates a significant anti-tussive effect without altering taste[1].
价 格：￥电议型 号：T10560产 地：中国大陆
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T10557BLM-IN-1；化合物 T10557BLM-IN-1
BLM-IN-1 is an effective Bloom syndrome protein (BLM) inhibitor (KD: 1.81 μM; IC50: 0.95 μM). It induces DNA damage response, apoptosis and proliferation arrest in cancer cells
价 格：￥电议型 号：T10557产 地：中国大陆
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T10552Bitopertin (R enantiomer)；化合物 T10552RO4917838 (R enantiomer)|||RG1678 (R enantiomer)|||Bitopertin R
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格：￥电议型 号：T10552产 地：中国大陆
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T1055Ifosfamide；异环磷酰胺NSC109724|||Isophosphamide；NSC109724|||Isophosphamide|||异环磷酰胺
Ifosfamide (NSC-109724) alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic activity. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes.
价 格：￥电议型 号：T1055产 地：中国大陆
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T10549Bisindolylmaleimide VIII acetate；化合物Bisindolylmaleimide VIII acetateRo 31-7549 acetate|||Bis VIII ac
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
价 格：￥电议型 号：T10549产 地：中国大陆
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T10547BioE-1115；化合物BioE-1115BioE-1115
BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
价 格：￥电议型 号：T10547产 地：中国大陆
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T10537BI-749327；化合物BI-749327BI-749327
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
价 格：￥电议型 号：T10537产 地：中国大陆
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T10536BI 703704；化合物 T10536BI 703704
BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].
价 格：￥电议型 号：T10536产 地：中国大陆
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T10531BGB-102；化合物 BGB-102JNJ-26483327；JNJ-26483327
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders and malformations.
价 格：￥电议型 号：T10531产 地：中国大陆
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T10530BF 227；化合物 T10530BF 227
BF 227 is a candidate for an amyloid imaging probe for PET (Ki: 4.3 nM for Aβ1-42 fibrils).
价 格：￥电议型 号：T10530产 地：中国大陆
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T10527Betrixaban-d6；化合物 T10527Betrixaban D6；Betrixaban D6
Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.
价 格：￥电议型 号：T10527产 地：中国大陆
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T10521ODM-207；化合物BET-IN-4BET-IN-4|||ODM207；BET-IN-4|||ODM207
ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.
价 格：￥电议型 号：T10521产 地：中国大陆
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T10517BET-BAY 002 (S enantiomer)；化合物 T10517BET-BAY 002 (S enantiomer)
The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).
价 格：￥电议型 号：T10517产 地：中国大陆
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T10507GPR40 Agonist 2；化合物 T10507GPR40 Agonist 2
GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.
价 格：￥电议型 号：T10507产 地：中国大陆
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T10501YM158 free base；化合物 T10501YM-57158；YM-57158
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).
价 格：￥电议型 号：T10501产 地：中国大陆
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T10497Benralizumab贝那利珠单抗BIW-8405|||MEDI-563
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, leading to a rapid depletion of eosinophils. Benralizumab is used for severe eosinophilic asthma and can be employed to prevent exacerbations of chronic obstructive pulmonary disease.
价 格：￥电议型 号：T10497产 地：中国大陆
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T10494Beclomethasone 17-propionate；化合物 T10494Beclomethasone-17-monopropionate|||17-BMP；Beclomethasone-17-m
Beclomethasone 17-propionate is an active metabolite of Beclomethasone dipropionate and an agonist of the glucocorticoid receptor (GR). It exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone 17-propionate effectively suppresses cytokine production in COPD lung macrophages.
价 格：￥电议型 号：T10494产 地：中国大陆
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T10493Beclabuvir；贝拉布韦BMS-791325；BMS-791325
Beclabuvir (BMS-791325) is a potent NS5A replication complex inhibitor that inhibits the activity of the NS5B protein expressed by HCV genotypes 1, 2, 4, and 5 and is used in the study of HCV infection.
价 格：￥电议型 号：T10493产 地：中国大陆
