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T15240Tazemetostat trihydrochloride;化合物 T15240EPZ-6438 trihydrochloride|||E-7438 trihydrochloride;EPZ-6438
Tazemetostat trihydrochloride is a selective and orally available inhibitor of EZH2 (IC50: 4 nM for rat EZH2). It inhibits the activity of human PRC2-containing wild-type EZH2 (Ki: 2.5 nM). It inhibits EZH2 (IC50s: 11 and 16 nM in peptide assay and nucleosome assay).
价 格:¥电议型 号:T15240产 地:中国大陆
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T15207Eleclazine hydrochloride;化合物Eleclazine hydrochlorideGS 6615 hydrochloride;GS 6615 hydrochloride
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
价 格:¥电议型 号:T15207产 地:中国大陆
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T15190(S,R,S)-AHPC-PEG4-NH2 hydrochloride;化合物 T15190E3 ligase Ligand-Linker Conjugates 7|||VH032-PEG4-NH2
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
价 格:¥电议型 号:T15190产 地:中国大陆
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T1517Benserazide hydrochloride;盐酸苄丝肼Benserazide HCl|||Serazide|||Ro 4-4602;Benserazide HCl|||盐酸苄丝肼|||Sera
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
价 格:¥电议型 号:T1517产 地:中国大陆
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T15136LDiZPK Hydrochloride (1337883-32-5 free base);化合物 T15136LDiZPK Hydrochloride;DiZPK Hydrochloride
DiZPK Hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.
价 格:¥电议型 号:T15136L产 地:中国大陆
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T15130Dilazep dihydrochloride;地拉卓二盐酸盐Dilazep dihydrochloride
Dilazep dihydrochloride is an adenosine uptake inhibitor. Dilazep dihydrochloride also inhibits the ischemic damage, membrane transport of nucleosides and platelet aggregation. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine.
价 格:¥电议型 号:T15130产 地:中国大陆
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T15112Dianicline dihydrochloride;化合物 T15112Dianicline dihydrochloride
Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
价 格:¥电议型 号:T15112产 地:中国大陆
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T1511Daunorubicin hydrochloride;盐酸柔红霉素Daunomycin HCl|||RP-13057 Hydrochloride|||Rubidomycin hydrochloride
Daunorubicin hydrochloride (Rubidomycin hydrochloride) is an anthracycline aminoglycoside, a topoisomerase II (Topo II) inhibitor. Daunorubicin hydrochloride inhibits DNA and RNA synthesis and has antitumor activity.
价 格:¥电议型 号:T1511产 地:中国大陆
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T15019LCUR61414 hydrochloride;化合物CUR61414 hydrochlorideCUR61414 hydrochloride (334998-36-6 Free base);CU
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM). CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.
价 格:¥电议型 号:T15019L产 地:中国大陆
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T14998Copanlisib dihydrochloride;库潘尼西盐酸BAY 80-6946 dihydrochloride;库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格:¥电议型 号:T14998产 地:中国大陆
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T14992Raxatrigine hydrochloride;化合物 T14992GSK-1014802 hydrochloride|||CNV1014802 (hydrochloride);GSK-10148
Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.
价 格:¥电议型 号:T14992产 地:中国大陆
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T14972Cirazoline hydrochloride;化合物 T14972LD 3098 hydrochloride;LD 3098 hydrochloride
Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
价 格:¥电议型 号:T14972产 地:中国大陆
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T14968Cinanserin hydrochloride;化合物Cinanserin hydrochlorideSQ 10643;SQ 10643
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus.
价 格:¥电议型 号:T14968产 地:中国大陆
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T1496Amiodarone hydrochloride;盐酸胺碘酮Amiodar|||Amiodarone HCl|||Nexterone;盐酸胺碘酮|||Amiodar|||Amiodarone HCl|
Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
价 格:¥电议型 号:T1496产 地:中国大陆
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T14928Agerafenib hydrochloride;化合物 T14928RXDX-105 hydrochloride|||CEP-32496 (hydrochloride);RXDX-105 hydro
Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).
价 格:¥电议型 号:T14928产 地:中国大陆
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T1488Procarbazine hydrochloride;盐酸甲基苄肼NSC-77213 HCl|||Procarbazine HCl;NSC-77213 HCl|||盐酸甲基苄肼|||Procarbaz
Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarbazine, after metabolic activation, appears to inhibit the trans-methylation of methionine into transfer RNA (t-RNA), thereby preventing protein synthesis and consequently DNA and RNA synthesis. This agent may also undergo auto-oxidation, resulting in the formation of cytotoxic fre
价 格:¥电议型 号:T1488产 地:中国大陆
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T14845BX471 hydrochloride化合物 T14845ZK-811752 hydrochloride
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
价 格:¥电议型 号:T14845产 地:中国大陆
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T1478Ondansetron hydrochloride dihydrate;盐酸昂丹司琼SN 307|||NSC 665799|||GR 38032|||Ondansetron hydrochloride
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
价 格:¥电议型 号:T1478产 地:中国大陆
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T1476LPramipexole dihydrochloride;盐酸普拉克索Pramipexole dihydrochloride
Pramipexole dihydrochloride could be used to treat Parkinson disease.
价 格:¥电议型 号:T1476L产 地:中国大陆
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T14767BP 897 hydrochloride;化合物BP 897 hydrochlorideBP 897 hydrochloride
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格:¥电议型 号:T14767产 地:中国大陆