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T1214588011-6561;化合物 8011-65618011-6561
1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent that has the potential for the research of bronchial asthma [1].
价 格:¥电议型 号:T121458产 地:中国大陆
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T12080MLS000544460;化合物MLS000544460MLS000544460
MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatase-mediated cell migration and has anticancer activity.
价 格:¥电议型 号:T12080产 地:中国大陆
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T12075ML-180;化合物ML-180SR1848;SR1848
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .
价 格:¥电议型 号:T12075产 地:中国大陆
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T1207Lovastatin;洛伐他汀MK-803|||Mevinolin;MK-803|||洛伐他汀|||Mevinolin
Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
价 格:¥电议型 号:T1207产 地:中国大陆
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T12068MK-8033 hydrochloride;化合物 T12068MK-8033 hydrochloride
MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC).
价 格:¥电议型 号:T12068产 地:中国大陆
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T1206Amsacrine安吖啶AMSA|||m-AMSA|||安吖啶|||CI-880|||acridinyl anisidide
Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. Amsacrine also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II.
价 格:¥电议型 号:T1206产 地:中国大陆
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T11980MD-224;化合物MD-224MD-224
MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) concept,and as a new class of anticancer agent.
价 格:¥电议型 号:T11980产 地:中国大陆
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T11915LY88074;化合物LY88074LY88074
LY88074 is a raloxifene analog in which the basic side chain has been removed. LY88074 is an agonist of ERβ (EC50 = 232 nM).This compound stimulates uterine cell proliferation.
价 格:¥电议型 号:T11915产 地:中国大陆
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T11914LY88074 Trimethyl ether;化合物 T11914LY88074 Trimethyl ether
LY88074 Trimethyl ether is useful for inhibiting various conditions associated with estrogen deprivation syndrome, such as osteoporosis and hyperlipidemia.
价 格:¥电议型 号:T11914产 地:中国大陆
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T11913LY88074 Methyl ether;化合物 T11913LY88074 Methyl ether
LY88074 Methyl ether is effective in inhibiting conditions associated with estrogen deprivation syndrome, such as osteoporosis and hyperlipidemia, which occur due to various estrogen-deficient states.
价 格:¥电议型 号:T11913产 地:中国大陆
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T11880LSD1-IN-5;化合物 T11880LSD1-IN-5
LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-5 is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM.
价 格:¥电议型 号:T11880产 地:中国大陆
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T1186988019-6075;化合物 8019-60758019-6075
Xanthine dehydrogenase, IC50: 170 nM
价 格:¥电议型 号:T118698产 地:中国大陆
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T1180LBlonanserin HCl;化合物 T1180LAD 5423|||AD5423|||AD-5423|||Blonanserin;AD 5423|||AD5423|||AD-5423|||Blon
Blonanserin is an antagonist of dopamine-D2 and serotonin-S2.
价 格:¥电议型 号:T1180L产 地:中国大陆
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T11809L162441;化合物 T11809L162441
L162441 is an antagonist of Angiotensin type 1 receptor.
价 格:¥电议型 号:T11809产 地:中国大陆
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T11808L162389;化合物 T11808L162389
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
价 格:¥电议型 号:T11808产 地:中国大陆
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T11807L002;化合物L002L002
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By blocking histone acetylation, p53 acetylation, and STAT3 activation, L002 shows potential in the treatment of hypertension‐induced cardiac hypertrophy and fibrogenesis.
价 格:¥电议型 号:T11807产 地:中国大陆
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T118066CDK9 inhibitor HH1;化合物CDK9 inhibitor HH18019-9719;8019-9719
CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
价 格:¥电议型 号:T118066产 地:中国大陆
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T11806L-NIO dihydrochloride;化合物 T11806L-NIO dihydrochloride
L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.
价 格:¥电议型 号:T11806产 地:中国大陆
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T11805L-NIL;化合物 L-NILL-NIL
L-NIL is a selective nitric oxide synthase (iNOS) inhibitor that reverses burn-induced activation of glycogen synthase kinase-3β in rat skeletal muscle and may slow the progression of squamous cell carcinoma lung.
价 格:¥电议型 号:T11805产 地:中国大陆
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T11804β3-AR agonist 2;化合物 T11804β3-AR agonist 2
β3-AR agonist 2 is a potent and selective agonist of β3-adrenergic receptor (β3-AR with an EC50 of 8 nM).
价 格:¥电议型 号:T11804产 地:中国大陆