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T11490LGSK2945 hydrochloride (1438071-12-5 free base);化合物 T11490LGSK2945 hydrochloride;GSK2945 hydrochlorid
GSK2945 hydrochloride is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM). It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
价 格:¥电议型 号:T11490L产 地:中国大陆
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T11487LFiboflapon sodium;化合物 T11487LGSK2190915 sodium salt|||AM-803 sodium;GSK2190915 sodium salt|||AM-803
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
价 格:¥电议型 号:T11487L产 地:中国大陆
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T11487Fiboflapon;化合物FiboflaponGSK2190915|||AM-803;GSK2190915|||AM-803
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.
价 格:¥电议型 号:T11487产 地:中国大陆
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T11486GSK2807 Trifluoroacetate;化合物GSK2807 TrifluoroacetateGSK2807 Trifluoroacetate
GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).
价 格:¥电议型 号:T11486产 地:中国大陆
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T11480GSK205;化合物 T11480GSK205
GSK205 is a selective TRPV4 antagonist (IC50: 4.19 μM) for inhibiting TRPV4-mediated Ca2+ influx.
价 格:¥电议型 号:T11480产 地:中国大陆
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T11380GDC-0927;化合物 T11380SRN-927;SRN-927
GDC-0927 is a novel,non-steroidal, potent, orally bioavailable, selective estrogen receptor antagonist.
价 格:¥电议型 号:T11380产 地:中国大陆
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T11369LGB-110 hydrochloride (1252806-70-4 free base);化合物 T11369LGB-110 hydrochloride;GB-110 hydrochloride
GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.
价 格:¥电议型 号:T11369L产 地:中国大陆
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T11335Fulvestrant (S enantiomer);化合物 T11335ZM 182780 S enantiomer|||ICI 182780 S enantiomer|||Fulvestrant
Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
价 格:¥电议型 号:T11335产 地:中国大陆
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T11334Fulvestrant (R enantiomer);化合物 T11334ICI 182780 R enantiomer|||ZD 9238 R enantiomer|||ZM 182780 R en
Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
价 格:¥电议型 号:T11334产 地:中国大陆
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T1133Nimesulide;尼美舒利R805;R805|||尼美舒利
Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.
价 格:¥电议型 号:T1133产 地:中国大陆
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T11286Fiduxosin;非多唑嗪A 185980.1|||ABT 980;A 185980.1|||ABT 980
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.
价 格:¥电议型 号:T11286产 地:中国大陆
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T11280FGFR4-IN-4;化合物 T11280FGFR4-IN-4
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
价 格:¥电议型 号:T11280产 地:中国大陆
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T1123Camptothecin喜树碱NSC-100880|||Campathecin|||喜树碱|||(S)-(+)-Camptothecin|||CPT
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
价 格:¥电议型 号:T1123产 地:中国大陆
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T11180Embramine;恩布拉敏Embramine
Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.
价 格:¥电议型 号:T11180产 地:中国大陆
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T11161EGFR-IN-7;化合物EGFR-IN-7TQB3804;TQB3804
EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.
价 格:¥电议型 号:T11161产 地:中国大陆
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T11131DW14800;化合物DW14800DW14800
DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.
价 格:¥电议型 号:T11131产 地:中国大陆
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T11080Dopropidil;多普吡地Dopropidil
Dopropidil is a new anti-angina pectoris calcium regulator, which has intracellular calcium antagonist activity and anti-ischemic effects in various predicted animal models.
价 格:¥电议型 号:T11080产 地:中国大陆
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T10983LDDP-38003 dihydrochloride;DDP-38003盐酸盐DDP-38003 dihydrochloride
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
价 格:¥电议型 号:T10983L产 地:中国大陆
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T10983DDP-38003 trihydrochloride;化合物 T10983DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.
价 格:¥电议型 号:T10983产 地:中国大陆
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T10980DCPLA-ME;化合物DCPLA-MEMethyl 8-[2-[(2-pentylcyclopropyl)methyl]cyclopropyl]octanoate|||2-[(2-Pentylcyc
DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative diseases. It is an effective PKCε activator.
价 格:¥电议型 号:T10980产 地:中国大陆