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已选条件
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T8561Apcinligase,pocket,anaphase-promoting,Apcin,recognition,complex,Inhibitor,Cdc20,Anaphase promoting c
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.
价 格:¥电议型 号:T8561产 地:中国大陆
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T6S1784BrazilinAutophagy,Apoptosis,inhibit,Brazilin,Inhibitor
1. Brazilin exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific signaling pathway. 3. Brazilin has anti-inflammatory property, can suppress mastitis and high glucose-induced vascular inflammatory process related with the inhibition of oxidative stress, CAMs expression, and NF-κB activation in HUVEC; may be useful to treat chronic inflammatory disorders includ
价 格:¥电议型 号:T6S1784产 地:中国大陆
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T6659SB 415286inhibit,GSK-3,Inhibitor,Glycogen synthase kinase 3,Glycogen synthase kinase-3,Apoptosis,SB-
SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.
价 格:¥电议型 号:T6659产 地:中国大陆
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T8297Gomisin NGomisin N,Inhibitor,Apoptosis,inhibit
Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits proliferation and induces apoptosis in cancer.
价 格:¥电议型 号:T8297产 地:中国大陆
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TJS1779Protosappanin AProtosappanin A,inhibit,JAK,Inhibitor,STAT,Janus kinase
Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/I??B/NF-??B inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show bot
价 格:¥电议型 号:TJS1779产 地:中国大陆
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T7969DipyrithioneDipyrithione,dermatophytosis,G1 phase,antiproliferative,antifungal,Apoptosis,Bacterial,a
Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity
价 格:¥电议型 号:T7969产 地:中国大陆
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T6623OxibendazoleInhibitor,Apoptosis,inhibit,Parasite,Oxibendazole
Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
价 格:¥电议型 号:T6623产 地:中国大陆
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TP2092LApelin-17 (human, bovine) acetateApelin17 (human, bovine) acetate,Apelin 17 (human, bovine) acetate
Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
价 格:¥电议型 号:TP2092L产 地:中国大陆
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T8496MAZ51EGFR,Apoptosis,growth,phosphorylation,Inhibitor,inhibit,PDGFRβ,MAZ51,MAZ 51,tumor,VEGF-D,indoli
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
价 格:¥电议型 号:T8496产 地:中国大陆
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T6537HO-3867inhibit,Inhibitor,Apoptosis,STAT,HO 3867,HO-3867
HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.
价 格:¥电议型 号:T6537产 地:中国大陆
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T6597Mosapride CitrateTAK-370,5-hydroxytryptamine Receptor,AS4370,TAK370,AS 4370,Inhibitor,Mosapride Citr
Mosapride Citrate, a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.
价 格:¥电议型 号:T6597产 地:中国大陆
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T6391ApocyninApocynin,Apoptosis,inhibit,Inhibitor,Autophagy
Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
价 格:¥电议型 号:T6391产 地:中国大陆
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T8931LICCB-19 hydrochlorideICCB19,ubiquitination,cIAP2,TRADD,cIAP1,RDA,ICCB 19 hydrochloride,Receptor-inte
ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
价 格:¥电议型 号:T8931L产 地:中国大陆
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TQ0077Ceftobiprolecephalosporin,Ceftobiprole,inhibit,vancomycin,penicillin,staphylococci,Bacterial,pyrroli
Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL).
价 格:¥电议型 号:TQ0077产 地:中国大陆
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T7188PiclidenosonPiclidenoson,diseases,P1 receptor,inhibit,Inhibitor,leukemia,CF101,Apoptosis,prostate,me
Piclidenoson, a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.
价 格:¥电议型 号:T7188产 地:中国大陆
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TP2494Acetyl Hexapeptide-49 AcetateAcetyl Hexapeptide49 Acetate,Acetyl Hexapeptide 49 Acetate
Acetyl Hexapeptide-49 Acetate solution ameliorates the discomfort of nagging pain and itch occurring in sensitive skin as a result of PAR-2-induced release of pro-inflammatory mediators, besides restoring the damaged barrier integrity.
价 格:¥电议型 号:TP2494产 地:中国大陆
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TN1891LupiwighteonePI3K,Apoptosis,antioxidant,Inhibitor,isoflavone,mTOR,antimicrobial,Akt,inhibit,Lupiwigh
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
价 格:¥电议型 号:TN1891产 地:中国大陆
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T6S2038Ziyuglycoside IIinhibit,Ziyuglycoside II,Apoptosis,Reactive Oxygen Species,Inhibitor
1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer and breast cancer cells, by cell cycle arrest and cell apoptosis.
价 格:¥电议型 号:T6S2038产 地:中国大陆
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T6671SirtinolSirtuin,Autophagy,Sirtinol,Apoptosis,Inhibitor,inhibit
Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
价 格:¥电议型 号:T6671产 地:中国大陆
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T9104TJ191cancer,TJ 191,Apoptosis,PMBC,MOLT-3,CEM,inhibit,C8166,Inhibitor,MOLT-4,MT-2,TJ191,HSB-2,TJ-191,
TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.
价 格:¥电议型 号:T9104产 地:中国大陆