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产品数：86101
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TN5888Toddaculininhibit,Toddaculin,osteoclast,Inhibitor,differentiation,leukemic,Apoptosis,osteoblast,anti
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis induc
价 格：￥电议型 号：TN5888产 地：中国大陆
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T6649(S)-(+)-RolipramTNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Ro
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
价 格：￥电议型 号：T6649产 地：中国大陆
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T8416Capmatinib xHClApoptosis,c-Met/HGFR,ATP competitive,inhibit,INC-280,Inhibitor,Capmatinib,SNU-5,INCB-
Capmatinib xHCl is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
价 格：￥电议型 号：T8416产 地：中国大陆
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TP1197SincalidePI3K/Akt,cardiovascular hormone,Inhibitor,SQ 19844,PI3K,Akt,Protein kinase B,Apoptosis,SQ-1
Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin, and also known as CCK-8.
价 格：￥电议型 号：TP1197产 地：中国大陆
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T9196IACS-13909antiproliferative,RTK,IACS13909,inhibit,SHP2,pMEK,anticancer,Inhibitor,MAPK,IACS 13909,pER
IACS-13909, a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
价 格：￥电议型 号：T9196产 地：中国大陆
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T6934PexmetinibAutophagy,p38 MAPK,ARRY 614,Pexmetinib,Inhibitor,ARRY614,inhibit
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
价 格：￥电议型 号：T6934产 地：中国大陆
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T9831MKC-1inhibit,mTOR,Apoptosis,Protein kinase B,PKB,MKC 1,renal cell cancer,Caki-1,Mammalian target of
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in
价 格：￥电议型 号：T9831产 地：中国大陆
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T8544Masitinib mesylateSCFR,PDGFR,c-Kit,Apoptosis,AB 1010,Src,CD117,Masitinib,Platelet-derived growth fac
Masitinib mesylate is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;PDGFRα/β;LynB,respectively).
价 格：￥电议型 号：T8544产 地：中国大陆
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T40108Inaxaplin
Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.
价 格：￥电议型 号：T40108产 地：中国大陆
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T6823E3330pancreatic cancer,TNF-α,E3330,REF-1,NF-κB,HIFs,Inhibitor,HIF-PH,Nuclear factor-kappaB,APX-3330,
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
价 格：￥电议型 号：T6823产 地：中国大陆
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T6893MK-886leukotriene,FLAP,5-LOX,5-LO activating protein,non-competitive,L-663536,L663536,keratin-1,Leuk
MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
价 格：￥电议型 号：T6893产 地：中国大陆
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T36683VedaprofenVedaprofen,Inhibitor,nonsteroidal,PM150,PM-150,Escherichia coli,inhibit,CERM-10202,CERM102
Vedaprofen inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.
价 格：￥电议型 号：T36683产 地：中国大陆
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T8705BOT-64IL-6,BOT64,I kappa B kinase,inhibit,inflammatory,BOT-64,NF-κb,RAW 264.7,IKK,IκB kinase,Inhibit
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase´s activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound
价 格：￥电议型 号：T8705产 地：中国大陆
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T16751Rilapladib
Rilapladib is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor.
价 格：￥电议型 号：T16751产 地：中国大陆
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TQ0079GNE-495MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor
GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).
价 格：￥电议型 号：TQ0079产 地：中国大陆
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T8421TED-347PPI,irreversible,protein-protein,YAP,allosteric,TEAD4?Yap1,transcriptional,glioblastoma,TED 3
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
价 格：￥电议型 号：T8421产 地：中国大陆
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TP2384LHexapeptide-10 AcetateHexapeptide10 Acetate,Hexapeptide 10 Acetate
Hexapeptide-10 Acetate is a synthetic peptide. It increases the synthesis of laminin V and α6-integrin to promote cell binding, with extraordinary visible skin restructuring and firming abilities.
价 格：￥电议型 号：TP2384L产 地：中国大陆
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TN1445BisabolangeloneBisabolangelone,Inhibitor,inhibit,p38 MAPK
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
价 格：￥电议型 号：TN1445产 地：中国大陆
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T6817DeguelinAutophagy,inhibit,Deguelin,Protein kinase B,Akt,PKB,Inhibitor,Apoptosis
Deguelin is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
价 格：￥电议型 号：T6817产 地：中国大陆
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TQ0131RocaglamideNF-κB,Nuclear factor-kappaB,Heat shock proteins,inhibit,Rocaglamide,Eukaryotic Initiation
Rocaglamide, isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.
价 格：￥电议型 号：TQ0131产 地：中国大陆
