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T73324PARL-IN-1;化合物 PARL-IN-1PARL-IN-1
PARL-IN-1, a potent PARL inhibitor, exhibits an IC50 value of 28 nM. It effectively inhibits PARL, consequently robustly activating the PINK1/Parkin pathway and promoting PINK1/Parkin-dependent mitophagy.
价 格:¥电议型 号:T73324产 地:中国大陆
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T73088Mavodelpar;化合物 MavodelparHPP593|||REN001|||REN001 ; HPP593;HPP593|||REN001|||REN001 ; HPP593
Mavodelpar (REN001), a selective PPARδ agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD).
价 格:¥电议型 号:T73088产 地:中国大陆
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T73067Isodispar B;化合物 Isodispar BIsodispar B
Isodispar B, an anticancer agent, effectively inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells while also inducing cell apoptosis. It exhibits cytotoxicity across a broad spectrum of cancer cell lines.
价 格:¥电议型 号:T73067产 地:中国大陆
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T73027PARP-2-IN-3;PARP-2 抑制剂3PARP-2-IN-3
PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS ??128-52-56-8
价 格:¥电议型 号:T73027产 地:中国大陆
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T73025PARP7-IN-12;化合物 PARP7-IN-12PARP7-IN-12
PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.
价 格:¥电议型 号:T73025产 地:中国大陆
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T73023PARP1-IN-12;化合物 PARP1-IN-12PARP1-IN-12
PARP1-IN-12, a potent inhibitor of PARP1, demonstrates an IC50 value of 2.99 nM. It exhibits antiproliferative effects, induces apoptosis, and causes cell cycle arrest in the G2/M phase. Additionally, PARP1-IN-12 induces DNA double-strand breaks (DSBs) in BRCA-deficient cells.
价 格:¥电议型 号:T73023产 地:中国大陆
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T73007PARP10-IN-2;化合物PARP10-IN-2PARP10-IN-2
PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and PARP15, with IC50 values of 27 μM and 11 μM, respectively.
价 格:¥电议型 号:T73007产 地:中国大陆
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T72862PARP-2/1-IN-2化合物 PARP-2/1-IN-2ABT-888对映体
PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].
价 格:¥电议型 号:T72862产 地:中国大陆
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T72554ARTD10/PARP10-IN-2;化合物 ARTD10/PARP10-IN-2ARTD10/PARP10-IN-2
ARTD10/PARP10-IN-2 is a potent, non-selective inhibitor of mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1, exhibiting IC50 values of 2.0 μM and 9.7 μM, respectively.
价 格:¥电议型 号:T72554产 地:中国大陆
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T72553ARTD10/PARP10-IN-1;ARTD10/PARP10抑制剂1ARTD10/PARP10-IN-1
ARTD10/PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly ADP-ribose polymerase-1 (ARTD1/PARP1), with potential anticancer and antitumour activity for the study of prostate and breast cancers.
价 格:¥电议型 号:T72553产 地:中国大陆
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T72437PARP1/2/TNKS1/2-IN-1;PARP1/2/TNKS1/2抑制剂1PARP1/2/TNKS1/2-IN-1
PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has potential anti-tumor activity and induces apoptosis.
价 格:¥电议型 号:T72437产 地:中国大陆
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T72397PARP11 inhibitor ITK7;化合物 PARP11 inhibitor ITK7ITK7;ITK7
PARP11 Inhibitor ITK7 (ITK7) is a potent, selective inhibitor of PARP11, demonstrating significant efficacy with an IC50 value of 14 nM. It is primarily utilized in research focused on cellular localization.
价 格:¥电议型 号:T72397产 地:中国大陆
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T71883Paraxazone;化合物 ParaxazoneParaxazone
Paraxazone is an antidepressant. It acts as a reversible inhibitor of the enzyme monoamine oxidase.
价 格:¥电议型 号:T71883产 地:中国大陆
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T71532Fondaparinux free base;化合物 Fondaparinux free baseFondaparinux free base
Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is a clinically approved anticoagulant pentasaccharide for the treatment of thrombotic diseases, displays better efficacy and biosafety than other heparin-based anticoagulant drugs.
价 格:¥电议型 号:T71532产 地:中国大陆
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T71327Paraxanthine-d6;化合物 Paraxanthine-d6Paraxanthine-d6
Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni
价 格:¥电议型 号:T71327产 地:中国大陆
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T7113Paradol;姜酮酚6-paradol|||[6]-Gingerone;姜酮酚|||6-paradol|||必理通|||[6]-Gingerone
Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities,neuroprotective Effects.
价 格:¥电议型 号:T7113产 地:中国大陆
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T70793Parogrelil Free Base;帕格雷利NM-702 Free Base;NM-702 Free Base
Parogrelil Free Base (NM-702 Free Base) is a selective phosphodiesterase 3 inhibitor with bronchodilatory and anti-inflammatory effects, inhibits leukotriene (LT)D(4) and histamine-induced constriction of isolated guinea pig tracheal strips, and can be used in the study of bronchial asthma.
价 格:¥电议型 号:T70793产 地:中国大陆
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T70762Senaparib hydrochloride;化合物 Senaparib hydrochlorideSenaparib hydrochloride
Senaparib hydrochloride is a potent and selective oral PARP1/2 inhibitor with strong antitumor activity.
价 格:¥电议型 号:T70762产 地:中国大陆
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T70536Idraparinux Na;化合物 Idraparinux NaIdraparinux Na
Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor
价 格:¥电议型 号:T70536产 地:中国大陆
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T70481,4-Naphthoquinone;1,4-萘醌α-Naphthoquinone|||Naphthalene-1,4-Dione|||P-Naphthoquinone|||para-naphthoq
1,4-Naphthoquinone (P-Naphthoquinone) was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase activity[1].
价 格:¥电议型 号:T7048产 地:中国大陆