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T15243Ertiprotafib;化合物 T15243PTP 112;PTP 112
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).
价 格:¥电议型 号:T15243产 地:中国大陆
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T15112Dianicline dihydrochloride;化合物 T15112Dianicline dihydrochloride
Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
价 格:¥电议型 号:T15112产 地:中国大陆
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T14939LCGP-42112 acetate;CGP-42112醋酸CGP-42112 acetate(127060-75-7 Free base);CGP-42112 acetate(127060-75-7
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.
价 格:¥电议型 号:T14939L产 地:中国大陆
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T14939CGP-42112化合物 T14939CGP42112A
CGP-42112 is an agonist of the Angiotensin-II subtype 2 receptor (AT2 R).
价 格:¥电议型 号:T14939产 地:中国大陆
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T14285AN11251;化合物 T14285AN11251
AN11251, a potent oral-active anti-Wolbachia agent, shows promise for treating onchocerciasis and lymphatic filariasis. Demonstrating EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines, it exhibits significant efficacy across different laboratory settings.
价 格:¥电议型 号:T14285产 地:中国大陆
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T14195ALS-8112;化合物 T14195ALS-8112
ALS-8112 is a inhibitor of respiratory syncytial virus (RSV) polymerase. The 5´-triphosphate form of ALS-8112 inhibits RSV polymerase (IC50: 0.02 μM).
价 格:¥电议型 号:T14195产 地:中国大陆
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T14112Acid-PEG6-mono-methyl ester;化合物 T14112Acid-PEG6-mono-methyl ester
Acid-PEG6-mono-methyl ester is a polyethylene glycol (PEG)-based PROTAC linker appropriate for synthesizing PROTACs. [1]
价 格:¥电议型 号:T14112产 地:中国大陆
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T13929TL13-112;化合物 T13929TL13-112
TL13-112 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.14 nM).
价 格:¥电议型 号:T13929产 地:中国大陆
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T13409LZK824859 hydrochloride (2271122-53-1 free base);化合物 T13409LZK824859 hydrochloride;ZK824859 hydrochlo
ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).
价 格:¥电议型 号:T13409L产 地:中国大陆
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T13324VUF11207 fumarate;化合物VUF11207 fumarateVUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
价 格:¥电议型 号:T13324产 地:中国大陆
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T131657Compound 0449-0112;化合物 0449-0112Compound 0449-0112
Compound 0449-0112 is a useful organic compound for research related to life sciences and the catalog number is T131657.
价 格:¥电议型 号:T131657产 地:中国大陆
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T13112L1Tat-NR2B9c acetate;化合物Tat-NR2B9c acetateTat-NR2B9c acetate (500992-11-0 Free base)|||NA-1 acetate;Ta
Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c acetate also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.
价 格:¥电议型 号:T13112L1产 地:中国大陆
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T13112LTat-NR2B9c TFA化合物 T13112LNA-1 (TFA)
Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.
价 格:¥电议型 号:T13112L产 地:中国大陆
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T131127Citroside A or B;化合物 Citroside A or BCitroside A or B
Citroside A or B is a useful organic compound for research related to life sciences and the catalog number is T131127.
价 格:¥电议型 号:T131127产 地:中国大陆
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T13112Tat-NR2B9c;化合物 Tat-NR2B9cTat-NR2Bct|||NA-1;Tat-NR2Bct|||NA-1
Tat-NR2B9c (NA-1) is a postsynaptic density-95 (PSD-95) inhibitor with neuroprotective and antiepileptic effects.Tat-NR2B9c inhibits PSD-95d2, PSD-95d1, and PSD-95, which prevents the activation of NMDA-induced NADPH oxidase in neurons, thereby blocking the production of superoxide, which reduces ischemic injury in the acute phase after stroke.
价 格:¥电议型 号:T13112产 地:中国大陆
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T12924Sitaxsentan;司他生坦TBC-11251|||IPI 1040;TBC-11251|||IPI 1040
Sitaxsentan (TBC-11251) is A selective endothelin A (ETA) receptor antagonist. Endothelin is an effective vasoconstrictor. Sitaxsentan blocks the binding of endothelin to its receptors, thereby eliminating the harmful effects of endothelin.
价 格:¥电议型 号:T12924产 地:中国大陆
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T12673LPF-06250112;化合物 T12673LPF-06250112
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).
价 格:¥电议型 号:T12673L产 地:中国大陆
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T12673(Rac)-PF-06250112;化合物 T12673(Rac)-PF-06250112
(Rac)-PF-0625011 is a racemic form of PF-06250112, a potent and highly selective BTK inhibitor that is orally bioavailable. It also demonstrates an inhibitory effect on the BMX non-receptor tyrosine kinase and TEC [1].
价 格:¥电议型 号:T12673产 地:中国大陆
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T126112Epiprocurcumenol;化合物 EpiprocurcumenolEpiprocurcumenol
Epiprocurcumenol is a useful organic compound for research related to life sciences and the catalog number is T126112.
价 格:¥电议型 号:T126112产 地:中国大陆
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T125112Stigmalactam;化合物 StigmalactamStigmalactam
Stigmalactam is a useful organic compound for research related to life sciences and the catalog number is T125112.
价 格:¥电议型 号:T125112产 地:中国大陆