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T11285FIDAS-5;化合物FIDAS-5FIDAS-5
FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.
价 格:¥电议型 号:T11285产 地:中国大陆
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T11284FIDAS-3;化合物FIDAS-3FIDAS-3
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.
价 格:¥电议型 号:T11284产 地:中国大陆
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T11283Fibracillin;非布拉西林Fibracillin
Fibracillin is a penicillin antibiotic.
价 格:¥电议型 号:T11283产 地:中国大陆
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T11282LFGTI-2734 mesylate (1247018-19-4 free base);化合物 T11282LFGTI-2734 mesylate;FGTI-2734 mesylate
FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282L产 地:中国大陆
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T11282FGTI-2734;化合物FGTI-2734FGTI-2734
FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localization of KRAS, addressing the issue of KRAS resistance and inhibiting the growth of mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282产 地:中国大陆
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T11281LFGI-106 tetrahydrochloride;化合物FGI-106 tetrahydrochlorideFGI-106 tetrahydrochloride
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective concentrations (EC50s) of 100 nM, 800 nM, and 400-900 nM, respectively. Additionally, it effectively inhibits non-hemorrhagic fever viruses, notably HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively, indicating its broad-spectrum antiviral potential.
价 格:¥电议型 号:T11281L产 地:中国大陆
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T11281FGI-106;化合物 T11281FGI-106
FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. Furthermore, it effectively inhibits non-hemorrhagic fever viruses such as HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively.
价 格:¥电议型 号:T11281产 地:中国大陆
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T11280FGFR4-IN-4;化合物 T11280FGFR4-IN-4
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
价 格:¥电议型 号:T11280产 地:中国大陆
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T1128Oxiracetam;奥拉西坦ISF2522;奥拉西坦|||ISF2522
Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
价 格:¥电议型 号:T1128产 地:中国大陆
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T11279FGFR1/DDR2 inhibitor 1;化合物FGFR1/DDR2 inhibitor 1FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
价 格:¥电议型 号:T11279产 地:中国大陆
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T11278FG8119;化合物FG8119NNC13-8119;NNC13-8119
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.
价 格:¥电议型 号:T11278产 地:中国大陆
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T11277FG 7142;化合物FG 7142ZK 39106|||LSU-65;ZK 39106|||LSU-65
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
价 格:¥电议型 号:T11277产 地:中国大陆
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T11276Fexofenadine-d6;非索非那定 d6MDL-16455-d6|||Terfenadine carboxylate-d6;MDL-16455-d6|||Terfenadine carboxy
Fexofenadine-d6 (MDL-16455-d6) is the deuterium substituent of Fexofenadine and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.
价 格:¥电议型 号:T11276产 地:中国大陆
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T11275Fesoterodine L-mandelate;非索罗定扁桃酸盐Fesoterodine L-mandelate
Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).
价 格:¥电议型 号:T11275产 地:中国大陆
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T11273Fenpiverinium D3 bromide;化合物 T11273Fenpiverinium D3 bromide
Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium D3 bromide is a deuterium labeled Fenpiverinium bromide.
价 格:¥电议型 号:T11273产 地:中国大陆
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T11272Fenmetozole Tosylate;化合物 T11272Fenmetozole Tosylate
Fenmetozole Tosylate , acts as an antidepressant drug. is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor,
价 格:¥电议型 号:T11272产 地:中国大陆
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T11271Fenclozine;化合物 T11271Fenclozine
Fenclozine is a non-steroidal antiinflammatory drug.
价 格:¥电议型 号:T11271产 地:中国大陆
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T1127Beclometasone dipropionate二丙酸倍氯米松Beclovent|||Beclomethasone dipropionate|||二丙酸倍氯米松|||丙酸倍氯米松|||Becona
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
价 格:¥电议型 号:T1127产 地:中国大陆
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T11269FD-IN-1;化合物 T11269FD-IN-1
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system.
价 格:¥电议型 号:T11269产 地:中国大陆
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T11268FD 12-9;化合物 T11268Ac12Az9;Ac12Az9
FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.
价 格:¥电议型 号:T11268产 地:中国大陆