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T11231ERRγ Inverse Agonist 1;化合物 T11231ERRγ Inverse Agonist 1
ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].
价 格:¥电议型 号:T11231产 地:中国大陆
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T11230ERRα antagonist-1;化合物ERRα 拮抗剂-1ERR+/- antagonist-1|||ERRa antagonist-1;ERR+/- antagonist-1|||ERRa an
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between ei
价 格:¥电议型 号:T11230产 地:中国大陆
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T1123Camptothecin喜树碱NSC-100880|||Campathecin|||喜树碱|||(S)-(+)-Camptothecin|||CPT
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
价 格:¥电议型 号:T1123产 地:中国大陆
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T11229Erlotinib-d6;化合物 T11229OSI-774 D6|||NSC 718781 D6|||CP-358774 D6;OSI-774 D6|||NSC 718781 D6|||CP-358
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
价 格:¥电议型 号:T11229产 地:中国大陆
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T11228ERK2 IN-1;化合物 T11228ERK2 IN-1
ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.
价 格:¥电议型 号:T11228产 地:中国大陆
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T11227L1Eravacycline HCl;盐酸伊拉瓦环素Eravacycline HCL(1207283-85-9 Free bse)|||TP-434 HCl;Eravacycline HCL(120728
Eravacycline HCl (TP-434 HCl) is potent antibiotic with broad-spectrum antibacterial activity.
价 格:¥电议型 号:T11227L1产 地:中国大陆
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T11227LEravacycline dihydrochloride;伊拉瓦环素盐酸盐TP-434-046|||TP-434 dihydrochloride;TP-434-046|||TP-434 dihydro
Eravacycline dihydrochloride (TP-434-046)?is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).
价 格:¥电议型 号:T11227L产 地:中国大陆
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T11227Eravacycline;伊拉瓦环素TP-434;TP-434
Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.
价 格:¥电议型 号:T11227产 地:中国大陆
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T11226ERK1/2 inhibitor 1;化合物 T11226ERK1/2 inhibitor 1
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
价 格:¥电议型 号:T11226产 地:中国大陆
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T11225ERK-IN-2;化合物 T11225ERK-IN-2
ERK-IN-2, an ERK2 inhibitor, exhibits an IC50 value of 1.8 nM. At doses greater than 10 μM, it may induce off-target toxicity and/or activity [1].
价 格:¥电议型 号:T11225产 地:中国大陆
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T11224Rineterkib;化合物RineterkibERK-IN-1;ERK-IN-1
Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
价 格:¥电议型 号:T11224产 地:中国大陆
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T11223Eriosematin;化合物 T11223Eriosematin
Eriosematin has anti-proliferative and apoptosis-inducing properties and is a compound extracted from the root of Flemingia philippinensis in the Philippines.
价 格:¥电议型 号:T11223产 地:中国大陆
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T11221ERAP1-IN-1;化合物ERAP1-IN-1ERAP1-IN-1
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activity toward a nonamer peptide representative of physiological substrates.
价 格:¥电议型 号:T11221产 地:中国大陆
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T11220LUK 227786;化合物T11220Lhydrochloride(150452-18-9 Free base)|||1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
价 格:¥电议型 号:T11220L产 地:中国大陆
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T11220ER21355;化合物 T11220ER21355
ER21355, utilized for the treatment of prostatic diseases, acts as a phosphodiesterase 5 (PDE5) inhibitor.
价 格:¥电议型 号:T11220产 地:中国大陆
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T1122Cephalothin sodium;头孢噻吩钠Cefalotin sodium|||Cephalothin|||Cefalotin;头孢噻吩钠|||Cefalotin sodium|||Cephal
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cros
价 格:¥电议型 号:T1122产 地:中国大陆
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T11219Equisetin;化合物 T11219Equisetin
Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence phenotypes in P. aeruginosa, presenting a potent lead for treating P. aeruginosa infections without hindering bacterial growth. This tetramate-containing natural product possesses antibiotic and cytotoxic properties, effectively inhibiting the growth of Gram-positive bacteria and
价 格:¥电议型 号:T11219产 地:中国大陆
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T11218ε-?Viniferin;Epsilon-白藜芦醇脱氢二聚体epsilon-Viniferin;epsilon-Viniferin|||Epsilon-白藜芦醇脱氢二聚体
ε-?Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
价 格:¥电议型 号:T11218产 地:中国大陆
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T11217Eplivanserin;依利色林SR-46349;依利色林|||SR-46349
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
价 格:¥电议型 号:T11217产 地:中国大陆
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T11216Eplivanserin (mixture)化合物 T11216Eplivanserin mixture|||SR-46349 (mixture)
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
价 格:¥电议型 号:T11216产 地:中国大陆