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  • T14359AVX 13616；化合物 T14359AVX 13616

    AVX 13616, Avexa´s leading antibacterial candidate, demonstrates significant in vivo antibacterial efficacy, especially against drug-resistant Staphylococcus pathogens, with an IC50 value of 2-4 ?g/ml (MICs) and is targeted as an antibacterial agent. Comparable in activity to mupirocin within a nasal decolonization model, AVX13616 necessitated only a single application for effectiveness. This compound, alongside others, exhibited broad-spectrum antibacterial action, achieving MICs of 2-4 m

    价 格：￥电议型 号：T14359产 地：中国大陆

  • T14358Avoralstat；AVORALSTATBCX4161；BCX4161

    Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.

    价 格：￥电议型 号：T14358产 地：中国大陆

  • T14357Spebrutinib besylate；化合物 T14357CC-292 (besylate)|||AVL-292 (benzenesulfonate)；CC-292 (besylate)|||AV

    Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).

    价 格：￥电议型 号：T14357产 地：中国大陆

  • T14356AVE-8134；化合物 T14356AVE-8134

    AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.

    价 格：￥电议型 号：T14356产 地：中国大陆

  • T14355AVE3085化合物 T14355AVE-3085

    AVE-3085 is a potent enhancer of endothelial nitric oxide synthase, and used for cardiovascular disease treatment.

    价 格：￥电议型 号：T14355产 地：中国大陆

  • T14354AVE 0991 sodium salt；化合物 T14354AVE 0991 sodium salt

    AVE 0991 competes for high-affinity binding of [125I]-Ang-(1-7) to bovine aortic endothelial cell membranes, with IC50 of 21±35 nM. AVE 0991 sodium salt is a nonpeptide and orally active Ang-(1-7) receptor Mas agonist.

    价 格：￥电议型 号：T14354产 地：中国大陆

  • T14353Auxinole；AuxinoleAuxinole

    Auxinole, a potent antagonist of TIR1/AFB auxin receptors, effectively binds to TIR1, inhibiting the formation of the TIR1-IAA-Aux/IAA complex. This action blocks auxin-responsive gene expression.

    价 格：￥电议型 号：T14353产 地：中国大陆

  • T14352Autotaxin-IN-1；化合物 T14352Autotaxin-IN-1

    Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship and it is used in treatment of osteoarthritis pain[1].

    价 格：￥电议型 号：T14352产 地：中国大陆

  • T14350Soblidotin；化合物SoblidotinAuristatin PE|||TZT-1027；Auristatin PE|||TZT-1027

    Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.

    价 格：￥电议型 号：T14350产 地：中国大陆

  • T1435Praziquantel吡喹酮吡喹酮|||Pyquiton|||Droncit|||Biltricide

    Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm´s musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads t

    价 格：￥电议型 号：T1435产 地：中国大陆

  • T14349Auristatin F；澳瑞他汀 FAuristatin F

    Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.

    价 格：￥电议型 号：T14349产 地：中国大陆

  • T14348Auristatin E；澳瑞他汀EAuristatin E

    Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in antibody-drug conjugates.

    价 格：￥电议型 号：T14348产 地：中国大陆

  • T14347Aureothricin；金色抗霉素Aureothricin

    Aureothricin, a dithiolopyrrolone (DTP) antibiotic originally derived from Streptomyces, demonstrates a broad-spectrum of antibacterial effectiveness. Additionally, it inhibits the adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].

    价 格：￥电议型 号：T14347产 地：中国大陆

  • T14346Aumitin；化合物AumitinAumitin

    Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial respiration by targeting complex I.

    价 格：￥电议型 号：T14346产 地：中国大陆

  • T14345Atropine methyl bromide；甲溴阿托品Methylatropine bromide；甲溴阿托品|||Methylatropine bromide

    Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.

    价 格：￥电议型 号：T14345产 地：中国大陆

  • T14344Atrimustine；阿莫司汀KM2210|||Bestrabucil；阿莫司汀|||KM2210|||Bestrabucil

    Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate. It has the antitumor activity.

    价 格：￥电议型 号：T14344产 地：中国大陆

  • T14343Atreleuton；化合物 T14343ABT-761|||VIA-2291；ABT-761|||VIA-2291

    Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity.

    价 格：￥电议型 号：T14343产 地：中国大陆

  • T14341ATN-224；四硫钼酸二胆碱Bis(choline)tetrathiomolybdate；四硫钼酸二胆碱|||Bis(choline)tetrathiomolybdate

    ATN-224 (Bis(choline)tetrathiomolybdate) inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor.

    价 格：￥电议型 号：T14341产 地：中国大陆

  • T14340Atiratecan；化合物 T14340TP300；TP300

    Atiratecan (TP300) is a prodrug of camptothecin analog CH0793076. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft models[1]. Atiratecan does not inhibit acetylcholinesterase (AChE) activities.

    价 格：￥电议型 号：T14340产 地：中国大陆

  • T1434Clarithromycin；克拉霉素A-56268；A-56268|||克拉霉素

    Clarithromycin (A-56268) is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classification of clarithromycin is Macrolides.

    价 格：￥电议型 号：T1434产 地：中国大陆

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