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T14339Athidathion;化合物 T14339GS-13006;GS-13006
Thiophos (GS-13006) is an insecticide, which is an organic phosphate ester.
价 格:¥电议型 号:T14339产 地:中国大陆
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T14338Atabecestat;化合物 T14338JNJ-54861911;JNJ-54861911
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer´s Disease treatment[1].
价 格:¥电议型 号:T14338产 地:中国大陆
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T14337Buloxibutid;化合物BuloxibutidAT2 receptor agonist C21;AT2 receptor agonist C21
Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and AT1 receptors, respectively.
价 格:¥电议型 号:T14337产 地:中国大陆
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T14336Allitinib;化合物AllitinibAST-1306|||ALS 1306;AST-1306|||ALS 1306
Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]
价 格:¥电议型 号:T14336产 地:中国大陆
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T14335ASP6432;化合物 T14335ASP6432
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
价 格:¥电议型 号:T14335产 地:中国大陆
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T14334ASP2535;化合物 T14334ASP2535
ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer´s disease[1].
价 格:¥电议型 号:T14334产 地:中国大陆
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T14333Asoxime dichloride;化合物Asoxime dichlorideTert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate|||Asox
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response.
价 格:¥电议型 号:T14333产 地:中国大陆
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T14332Asoprisnil;化合物 T14332J867;J867
Asoprisnil is a selective modulator of progesterone receptor.
价 格:¥电议型 号:T14332产 地:中国大陆
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T14331Gusacitinib;化合物GusacitinibASN-002;ASN-002
Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
价 格:¥电议型 号:T14331产 地:中国大陆
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T14330Ascochlorin;化合物 T14330Ilicicolin D;Ilicicolin D
Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, primarily exerts its anti-tumor properties by inhibiting the STAT3 signaling pathway. It induces apoptosis and possesses anti-inflammatory activity[1][2][3].
价 格:¥电议型 号:T14330产 地:中国大陆
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T1433Ritodrine hydrochloride;盐酸利托君DU21220|||Ritodrine HCl|||NSC 291565;DU21220|||盐酸利托君|||Ritodrine HCl|||
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vasc
价 格:¥电议型 号:T1433产 地:中国大陆
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T14329Ascamycin;化合物AscamycinAscamycin
Ascamycin is a 5´-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL respectively.
价 格:¥电议型 号:T14329产 地:中国大陆
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T14328AS2521780;化合物 T14328AS2521780
AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).
价 格:¥电议型 号:T14328产 地:中国大陆
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T14327AS1949490;化合物AS1949490AS1949490
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
价 格:¥电议型 号:T14327产 地:中国大陆
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T14326AS-35;化合物 AS-35AS-35
AS-35 is an orally available, selective and potent leukotrienes antagonist that inhibits LTC4, LTD4 and LTE4-induced ileus contractions.AS-35 has antiallergic properties and inhibits leukotriene synthesis.
价 格:¥电议型 号:T14326产 地:中国大陆
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T14325Arterolane;青蒿氧烷OZ 277|||RBx 11160;OZ 277|||青蒿氧烷|||RBx 11160
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
价 格:¥电议型 号:T14325产 地:中国大陆
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T14324Artemisone;青蒿酮BAY 44-9585|||Artemifone;BAY 44-9585|||Artemifone|||青蒿酮
Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
价 格:¥电议型 号:T14324产 地:中国大陆
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T14323ARQ 531;化合物ARQ 531ARQ 531
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity, with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.
价 格:¥电议型 号:T14323产 地:中国大陆
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T14322ARP-100;化合物ARP-100MMP-2 Inhibitor III;MMP-2 Inhibitor III
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1´ pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM) and MMP-9 (0.2 μM)[1][2].
价 格:¥电议型 号:T14322产 地:中国大陆
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T14321ARN19874;化合物 T14321ARN19874
ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor. With an IC50 of ~34 μM[1].
价 格:¥电议型 号:T14321产 地:中国大陆