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T2650MK-8245MK8245;MK 8245
MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.
价 格:¥电议型 号:T2650产 地:中国大陆
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T26296TriparanolNSC 65345;NSC65345;NSC-65345
Triparanol is an antilipemic with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
价 格:¥电议型 号:T26296产 地:中国大陆
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T2622GSK 650394GSK650394
GSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.
价 格:¥电议型 号:T2622产 地:中国大陆
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T25865NG-Nitroarginine methyl esterω-Nitroarginine methyl;L-NAME
NG-Nitroarginine methyl ester is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.
价 格:¥电议型 号:T25865产 地:中国大陆
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T2565Hesperetin
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
价 格:¥电议型 号:T2565产 地:中国大陆
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T25465GS143GS 143;GS-143
GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup-presses NF-κB acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthm
价 格:¥电议型 号:T25465产 地:中国大陆
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T25399ETP-45658ETP 45658;ETP45658
ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).
价 格:¥电议型 号:T25399产 地:中国大陆
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T24656PQ-10A-844337;A 844337;A844337;PQ 10;PQ10
PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
价 格:¥电议型 号:T24656产 地:中国大陆
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T2465PF-562271PF562271;PF 562271
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
价 格:¥电议型 号:T2465产 地:中国大陆
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T2365PilaralisibXL-147;SAR245408
Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Glioblastoma, and Breast Cancer, am
价 格:¥电议型 号:T2365产 地:中国大陆
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T2322Fimasartan非马沙坦;Kanarb;BR-A-657
Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has shown to be safe in clinical trials.
价 格:¥电议型 号:T2322产 地:中国大陆
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T22965MDL 72527N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride
MDL 72527 is a polyamine oxidase (POA) inhibitor
价 格:¥电议型 号:T22965产 地:中国大陆
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T22811LGR 94800 acetateGR 94800 acetate (141636-65-9 free base)
GR 94800 acetate is a potent and selective neurokinin 2(NK-2) antagonist.
价 格:¥电议型 号:T22811L产 地:中国大陆
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T2277Losmapimod6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺;洛批莫德;SB856553;GSK-AHAB;GW856553;GW856553
Losmapimod (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
价 格:¥电议型 号:T2277产 地:中国大陆
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T22665PD 128042CI 976
CI 976 is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multiple membrane trafficking steps.
价 格:¥电议型 号:T22665产 地:中国大陆
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T22654Selfotel塞福太;CGS 19755;LY-272541
CGS 19755 is a selective, competitive NMDA antagonist that inhibits [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid binding to NMDA-type receptors with IC50 of 50 nM.
价 格:¥电议型 号:T22654产 地:中国大陆
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T2265BimiralisibPQR309;PI3K-IN-2;5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-ami
PI3K-IN-2 is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in
价 格:¥电议型 号:T2265产 地:中国大陆
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T2260GW96622-氯-5-硝基-N-苯基苯酰胺;GW 9662;TIMTEC-BB SBB006523
GW9662 is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.
价 格:¥电议型 号:T2260产 地:中国大陆
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T2257AdipoRonSC-396658;2-(4-苯甲酰苯氧基)-N-[1-(苯基甲基)-4-哌啶基]乙酰胺
AdipoRon is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).
价 格:¥电议型 号:T2257产 地:中国大陆