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T17652Boc-NH-C12-NH2(12-氨基十二烷基)氨基甲酸叔丁酯
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17652产 地:中国大陆
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T1765Erastin
Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
价 格:¥电议型 号:T1765产 地:中国大陆
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T17565Biotin-PEG2-C2-iodoacetamide生物素-二聚乙二醇-碘乙酰胺;Biotin-PEG2-iodoacetamide
Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17565产 地:中国大陆
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T17465Azide-PEG12-Tos叠氮-十二聚乙二醇-对甲苯磺酰酯
Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17465产 地:中国大陆
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T17265XimelagatranH 376-95;H-37695;H 376/95;EXANTA;H37695;H 37695;希美加群
Ximelagatran, a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active agent melagatran in vivo.
价 格:¥电议型 号:T17265产 地:中国大陆
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T17065TFMB-(R)-2-HG
TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.
价 格:¥电议型 号:T17065产 地:中国大陆
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T17011TCH-165
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.
价 格:¥电议型 号:T17011产 地:中国大陆
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T16850SB-265610GSK-CXCR2
SB-265610 is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively).
价 格:¥电议型 号:T16850产 地:中国大陆
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T16812RWJ-67657JNJ 3026582
RWJ-67657 is an orally active and selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively). RWJ-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect.
价 格:¥电议型 号:T16812产 地:中国大陆
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T16801(RS)-(Tetrazol-5-yl)glycineD,L-(tetrazol-5-yl)glycine;LY 285265
(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D, and GluN1/GluN2A, respectively.
价 格:¥电议型 号:T16801产 地:中国大陆
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T1665DaptomycinLY146032;达托霉素
Daptomycin is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
价 格:¥电议型 号:T1665产 地:中国大陆
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T1659Melatonin松果体素;褪黑素;Melatonine;N-Acetyl-5-methoxytryptamine
Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood,
价 格:¥电议型 号:T1659产 地:中国大陆
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T1658SelenomethionineDL-硒代蛋氨酸;硒代蛋氨酸;Seleno-DL-methionine;DL-Selenomethionine
DL-Selenomethionine is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methionine with no effects on protein structure and function, pro
价 格:¥电议型 号:T1658产 地:中国大陆
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T16579Pro-xylaneHydroxypropyl tetrahydropyrantriol;玻色因
Pro-Xylane is a biochemical which induces neo-synthesis of matrix proteins. It is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane is the first example of ´Green´ chemical used
价 格:¥电议型 号:T16579产 地:中国大陆
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T16571PranidipineOPC-13340;普拉地平
Pranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive ac
价 格:¥电议型 号:T16571产 地:中国大陆
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T1657Varenicline Tartrate酒石酸伐尼克兰;酒石酸伐仑克林;Chantix tartrate;CP 526555-18;Champix tartrate
Varenicline tartrate is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.
价 格:¥电议型 号:T1657产 地:中国大陆
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T16569PraliciguatIW-1973
Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
价 格:¥电议型 号:T16569产 地:中国大陆
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T16567PQR530PQR-530
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity.
价 格:¥电议型 号:T16567产 地:中国大陆
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T16566Propyl pyrazole triolPPT
Propyl pyrazole triol is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).
价 格:¥电议型 号:T16566产 地:中国大陆
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T16563LPozanicline hydrochloride
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAC
价 格:¥电议型 号:T16563L产 地:中国大陆