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T11791KW-6055;化合物 T11791KW-6055
KW-6055 has anti-amnesic activity, is a benzylpyridine derivative.
价 格:¥电议型 号:T11791产 地:中国大陆
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T11766LEltanexor;化合物EltanexorONO-7706|||KPT-8602|||ATG-016;ONO-7706|||KPT-8602|||ATG-016
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines.
价 格:¥电议型 号:T11766L产 地:中国大陆
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T11766Eltanexor Z-isomer化合物 T11766KPT-8602 (Z-isomer)
Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.
价 格:¥电议型 号:T11766产 地:中国大陆
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T11760KIN101;3-(4-溴苯基)-4-氧代-7-[(甲磺酰基)氧基]-4H-色烯3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene;
KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and RSV.
价 格:¥电议型 号:T11760产 地:中国大陆
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T1174Topotecan hydrochloride;盐酸拓扑替康SKF 104864A|||SKFS 104864A|||NSC609699|||Nogitecan HCl|||NSC 609669|||
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
价 格:¥电议型 号:T1174产 地:中国大陆
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T11733K-604 dihydrochloride;化合物K-604 dihydrochlorideK-604 dihydrochloride
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.
价 格:¥电议型 号:T11733产 地:中国大陆
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T11706Londamocitinib;化合物LondamocitinibAZD4604;AZD4604
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
价 格:¥电议型 号:T11706产 地:中国大陆
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T11660Insulin levels modulator;化合物 T11660Insulin levels modulator
Insulin level regulators can be used to treat diabetes.
价 格:¥电议型 号:T11660产 地:中国大陆
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T11609ICI 153110;化合物 T11609ICI 153110
ICI 153110 is an orally active phosphodiesterase inhibitor with both inotropic and vasodilating properties. It is designed for the treatment of congestive cardiac failure.
价 格:¥电议型 号:T11609产 地:中国大陆
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T11608Epanolol;化合物 T11608Visacor|||ICI141292;Visacor|||ICI141292
Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
价 格:¥电议型 号:T11608产 地:中国大陆
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T11607ICI 118,551 hydrochloride;化合物ICI 118,551 hydrochlorideICI 118551 hydrochloride;ICI 118551 hydrochlor
ICI 118,551 hydrochloride (ICI 118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist (Kis: 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors).
价 格:¥电议型 号:T11607产 地:中国大陆
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T11606ICA-105665;化合物 T11606PF-04895162;PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格:¥电议型 号:T11606产 地:中国大陆
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T11605(-)-Ibuprofenamide;化合物 T11605(R)-Ibuprofenamide;(R)-Ibuprofenamide
(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.
价 格:¥电议型 号:T11605产 地:中国大陆
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T11604Ibuprofen-d3;化合物 T11604Ibuprofen D3|||(±)-Ibuprofen D3;Ibuprofen D3|||(±)-Ibuprofen D3
Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).
价 格:¥电议型 号:T11604产 地:中国大陆
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T11603Ibrutinib-MPEA;化合物 T11603Ibrutinib-MPEA
Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies.
价 格:¥电议型 号:T11603产 地:中国大陆
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T11602Ibrutinib dimer;依鲁替尼二聚体Ibrutinib dimer
Ibrutinib dimer is an impurity of Ibrutinib. IIbrutinib dimer is a Dimer of Ibrutinib. Ibrutinib is an irreversible Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T11602产 地:中国大陆
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T11601Ibrutinib-d5;化合物 T11601PCI-32765 D5|||Ibrutinib D5;PCI-32765 D5|||Ibrutinib D5
Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.
价 格:¥电议型 号:T11601产 地:中国大陆
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T11600IBR2;化合物IBR2Isoquinoline;Isoquinoline
IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RAD51 protein degradation, inhibiting cancer cell growth, and inducing apoptosis, IBR2 has proved to be an effective compound in these aspects.
价 格:¥电议型 号:T11600产 地:中国大陆
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T1160Fusidic acid;夫西地酸Fusidine;Fusidine|||夫西地酸
Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.
价 格:¥电议型 号:T1160产 地:中国大陆
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T11581HSR6071;化合物HSR6071HSR6071
HSR6071 is a novel orally active and potent anti-allergic agent with inhibitory effects on passive cutaneous anaphylaxis. HSR6071 showed anti-asthmatic activity in a rat model of experimental asthma.
价 格:¥电议型 号:T11581产 地:中国大陆